SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dut'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V7P_A_BEZA430_0 (AMIDOHYDROLASE FAMILY PROTEIN)	1dut	DUTP PYROPHOSPHATASE (Feline immunodeficiency virus)	4 / 7	ILE A 58 GLY A 59 SER A 60 SER A 57	None	0.90A	3v7pA-1dutA: 0.0	3v7pA-1dutA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BLV_B_SAMB1281_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	1dut	DUTP PYROPHOSPHATASE (Feline immunodeficiency virus)	5 / 12	GLY A 54 GLY A 59 SER A 56 LEU A 101 GLY A 17	None	1.25A	4blvB-1dutA: undetectable	4blvB-1dutA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UUU_A_SAMA1546_0 (CYSTATHIONINE BETA-SYNTHASE)	1dut	DUTP PYROPHOSPHATASE (Feline immunodeficiency virus)	5 / 11	LEU A 92 ASP A 19 ALA A 22 VAL A 80 ILE A 53	None	1.31A	4uuuA-1dutA: 0.0 4uuuB-1dutA: 0.0	4uuuA-1dutA: 20.38 4uuuB-1dutA: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JS5_A_ASCA202_0 (CYTOCHROME C')	1dut	DUTP PYROPHOSPHATASE (Feline immunodeficiency virus)	3 / 3	CYH A 106 LYS A 107 HIS A 108	None	1.24A	5js5A-1dutA: undetectable	5js5A-1dutA: 21.32

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3V7P_A_BEZA430_0","AMIDOHYDROLASE FAMILY PROTEIN","1dut","DUTP PYROPHOSPHATASE","Feline immunodeficiency virus",4,"ILE A  58;GLY A  59;SER A  60;SER A  57","None","0.90A","3v7pA-1dutA:0.0","3v7pA-1dutA:16.43"],["4BLV_B_SAMB1281_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","1dut","DUTP PYROPHOSPHATASE","Feline immunodeficiency virus",5,"GLY A  54;GLY A  59;SER A  56;LEU A 101;GLY A  17","None","1.25A","4blvB-1dutA:undetectable","4blvB-1dutA:21.15"],["4UUU_A_SAMA1546_0","CYSTATHIONINE BETA-SYNTHASE","1dut","DUTP PYROPHOSPHATASE","Feline immunodeficiency virus",5,"LEU A  92;ASP A  19;ALA A  22;VAL A  80;ILE A  53","None","1.31A","4uuuA-1dutA:0.0;4uuuB-1dutA:0.0","4uuuA-1dutA:20.38;4uuuB-1dutA:20.38"],["5JS5_A_ASCA202_0","CYTOCHROME C'","1dut","DUTP PYROPHOSPHATASE","Feline immunodeficiency virus",3,"CYH A 106;LYS A 107;HIS A 108","None","1.24A","5js5A-1dutA:undetectable","5js5A-1dutA:21.32"]]