SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dv8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 189
TRP A 174
 None
 1.26A 1c4dC-1dv8A:
undetectable
1c4dD-1dv8A:
undetectable		 1c4dC-1dv8A:
15.94
1c4dD-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.29A 1c4dC-1dv8A:
undetectable
1c4dD-1dv8A:
undetectable		 1c4dC-1dv8A:
15.94
1c4dD-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 PHE A 257
ARG A 270
ASN A 208
 None
CL  A1004 (-4.4A)
None
 0.87A 1xzxX-1dv8A:
0.0		 1xzxX-1dv8A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 174
TRP A 210
 None
 1.11A 2xdcA-1dv8A:
undetectable
2xdcB-1dv8A:
undetectable		 2xdcA-1dv8A:
15.94
2xdcB-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 210
TRP A 174
 None
 1.38A 2xdcA-1dv8A:
undetectable
2xdcB-1dv8A:
undetectable		 2xdcA-1dv8A:
15.94
2xdcB-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 174
VAL A 275
TRP A 210
 None
 1.37A 2xdcA-1dv8A:
undetectable
2xdcB-1dv8A:
undetectable		 2xdcA-1dv8A:
15.94
2xdcB-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.13A 2xdcA-1dv8A:
undetectable
2xdcB-1dv8A:
undetectable		 2xdcA-1dv8A:
15.94
2xdcB-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 174
TRP A 210
 None
 1.24A 2xdcC-1dv8A:
undetectable
2xdcD-1dv8A:
undetectable		 2xdcC-1dv8A:
15.94
2xdcD-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.07A 2xdcC-1dv8A:
undetectable
2xdcD-1dv8A:
undetectable		 2xdcC-1dv8A:
15.94
2xdcD-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.10A 2xdcE-1dv8A:
undetectable
2xdcF-1dv8A:
undetectable		 2xdcE-1dv8A:
15.94
2xdcF-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 174
TRP A 210
 None
 1.10A 2y5mA-1dv8A:
undetectable
2y5mB-1dv8A:
undetectable		 2y5mA-1dv8A:
15.94
2y5mB-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 210
TRP A 174
 None
 1.36A 2y5mA-1dv8A:
undetectable
2y5mB-1dv8A:
undetectable		 2y5mA-1dv8A:
15.94
2y5mB-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.08A 2y5mE-1dv8A:
undetectable
2y5mF-1dv8A:
undetectable		 2y5mE-1dv8A:
15.94
2y5mF-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 174
TRP A 210
 None
 1.10A 2y6nA-1dv8A:
undetectable
2y6nB-1dv8A:
undetectable		 2y6nA-1dv8A:
15.94
2y6nB-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 210
TRP A 174
 None
 1.37A 2y6nA-1dv8A:
undetectable
2y6nB-1dv8A:
undetectable		 2y6nA-1dv8A:
15.94
2y6nB-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 174
VAL A 275
TRP A 210
 None
 1.36A 2y6nA-1dv8A:
undetectable
2y6nB-1dv8A:
undetectable		 2y6nA-1dv8A:
15.94
2y6nB-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.11A 2y6nA-1dv8A:
undetectable
2y6nB-1dv8A:
undetectable		 2y6nA-1dv8A:
15.94
2y6nB-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.06A 2y6nC-1dv8A:
undetectable
2y6nD-1dv8A:
undetectable		 2y6nC-1dv8A:
15.94
2y6nD-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 275
TRP A 174
 None
 1.06A 2y6nE-1dv8A:
undetectable
2y6nF-1dv8A:
undetectable		 2y6nE-1dv8A:
15.94
2y6nF-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 ASP A 253
GLU A 252
GLY A 251
 CA  A1001 (-3.4A)
CA  A1002 ( 2.9A)
None
 0.71A 3w9tA-1dv8A:
0.0		 3w9tA-1dv8A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 VAL A 275
TRP A 174
TRP A 210
 None
 1.15A 3zq8A-1dv8A:
undetectable
3zq8B-1dv8A:
undetectable		 3zq8A-1dv8A:
15.94
3zq8B-1dv8A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens) 		3 / 3 TRP A 210
VAL A 189
TRP A 174
 None
 1.00A 3zq8C-1dv8A:
undetectable
3zq8D-1dv8A:
undetectable		 3zq8C-1dv8A:
15.94
3zq8D-1dv8A:
15.94