SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dvk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_A_H4BA1600_1
(NITRIC-OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.46A 1fopA-1dvkA:
0.0
1fopB-1dvkA:
1.6		 1fopA-1dvkA:
18.14
1fopB-1dvkA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 1k2rA-1dvkA:
0.2
1k2rB-1dvkA:
1.4		 1k2rA-1dvkA:
18.45
1k2rB-1dvkA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 1k2rA-1dvkA:
0.1
1k2rB-1dvkA:
1.4		 1k2rA-1dvkA:
18.45
1k2rB-1dvkA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 1k2sA-1dvkA:
undetectable
1k2sB-1dvkA:
1.6		 1k2sA-1dvkA:
18.45
1k2sB-1dvkA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.45A 1k2sA-1dvkA:
undetectable
1k2sB-1dvkA:
1.6		 1k2sA-1dvkA:
18.45
1k2sB-1dvkA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 1k2tA-1dvkA:
2.2
1k2tB-1dvkA:
0.0		 1k2tA-1dvkA:
18.45
1k2tB-1dvkA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 1k2tA-1dvkA:
2.2
1k2tB-1dvkA:
0.0		 1k2tA-1dvkA:
18.45
1k2tB-1dvkA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 1k2uA-1dvkA:
1.6
1k2uB-1dvkA:
1.4		 1k2uA-1dvkA:
18.45
1k2uB-1dvkA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.45A 1k2uA-1dvkA:
1.6
1k2uB-1dvkA:
1.4		 1k2uA-1dvkA:
18.45
1k2uB-1dvkA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 163
VAL A 166
LEU A 170
 None
 0.33A 1mz9B-1dvkA:
undetectable		 1mz9B-1dvkA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 1nsiA-1dvkA:
1.6
1nsiB-1dvkA:
0.6		 1nsiA-1dvkA:
18.52
1nsiB-1dvkA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 1nsiC-1dvkA:
0.1
1nsiD-1dvkA:
1.4		 1nsiC-1dvkA:
18.52
1nsiD-1dvkA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 8 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 1om5A-1dvkA:
undetectable
1om5B-1dvkA:
undetectable		 1om5A-1dvkA:
16.82
1om5B-1dvkA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.39A 1om5A-1dvkA:
1.7
1om5B-1dvkA:
1.4		 1om5A-1dvkA:
16.82
1om5B-1dvkA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 1p6hA-1dvkA:
1.4
1p6hB-1dvkA:
1.6		 1p6hA-1dvkA:
16.82
1p6hB-1dvkA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.46A 1p6lA-1dvkA:
1.5
1p6lB-1dvkA:
1.7		 1p6lA-1dvkA:
17.92
1p6lB-1dvkA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 1p6mA-1dvkA:
undetectable
1p6mB-1dvkA:
undetectable		 1p6mA-1dvkA:
17.92
1p6mB-1dvkA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 1p6nA-1dvkA:
1.1
1p6nB-1dvkA:
1.3		 1p6nA-1dvkA:
17.92
1p6nB-1dvkA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 1rs7A-1dvkA:
1.4
1rs7B-1dvkA:
1.5		 1rs7A-1dvkA:
16.82
1rs7B-1dvkA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.46A 1rs8A-1dvkA:
undetectable
1rs8B-1dvkA:
2.6		 1rs8A-1dvkA:
17.92
1rs8B-1dvkA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 230
LEU A 155
ILE A 117
LEU A 167
ILE A 233
 None
 1.00A 1rx2A-1dvkA:
undetectable		 1rx2A-1dvkA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 1zvlA-1dvkA:
1.6
1zvlB-1dvkA:
0.9		 1zvlA-1dvkA:
16.63
1zvlB-1dvkA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.46A 1zvlA-1dvkA:
1.6
1zvlB-1dvkA:
0.9		 1zvlA-1dvkA:
16.63
1zvlB-1dvkA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 1zzsA-1dvkA:
2.5
1zzsB-1dvkA:
1.7		 1zzsA-1dvkA:
17.92
1zzsB-1dvkA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 147
LEU A 121
ARG A 235
LEU A 236
ALA A 142
 None
 0.98A 2bxeA-1dvkA:
1.2		 2bxeA-1dvkA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		5 / 10 LEU A 147
LEU A 121
ARG A 235
LEU A 236
ALA A 142
 None
 0.97A 2bxeB-1dvkA:
undetectable		 2bxeB-1dvkA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		5 / 10 LEU A 147
LEU A 121
LEU A 236
ILE A 233
ALA A 142
 None
 1.12A 2bxeB-1dvkA:
undetectable		 2bxeB-1dvkA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 2g6hA-1dvkA:
1.4
2g6hB-1dvkA:
1.6		 2g6hA-1dvkA:
18.81
2g6hB-1dvkA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 2g6kA-1dvkA:
1.5
2g6kB-1dvkA:
1.4		 2g6kA-1dvkA:
18.81
2g6kB-1dvkA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 2hx4A-1dvkA:
1.6
2hx4B-1dvkA:
1.4		 2hx4A-1dvkA:
17.18
2hx4B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 2hx4A-1dvkA:
1.6
2hx4B-1dvkA:
1.4		 2hx4A-1dvkA:
17.18
2hx4B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 2nsiA-1dvkA:
0.5
2nsiB-1dvkA:
0.5		 2nsiA-1dvkA:
18.52
2nsiB-1dvkA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 2nsiC-1dvkA:
0.5
2nsiD-1dvkA:
0.5		 2nsiC-1dvkA:
18.52
2nsiD-1dvkA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 2nsiC-1dvkA:
0.5
2nsiD-1dvkA:
0.5		 2nsiC-1dvkA:
18.52
2nsiD-1dvkA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 3b3nA-1dvkA:
1.7
3b3nB-1dvkA:
1.5		 3b3nA-1dvkA:
17.18
3b3nB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 8 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.44A 3b3pA-1dvkA:
1.4
3b3pB-1dvkA:
2.0		 3b3pA-1dvkA:
17.18
3b3pB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 147
ARG A 235
LEU A 236
ALA A 142
 None
 1.12A 3b9mA-1dvkA:
undetectable		 3b9mA-1dvkA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 3e7gA-1dvkA:
0.6
3e7gB-1dvkA:
1.2		 3e7gA-1dvkA:
18.82
3e7gB-1dvkA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 3e7gA-1dvkA:
0.6
3e7gB-1dvkA:
1.2		 3e7gA-1dvkA:
18.82
3e7gB-1dvkA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 3hsoA-1dvkA:
0.2
3hsoB-1dvkA:
1.2		 3hsoA-1dvkA:
17.18
3hsoB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 3jt3A-1dvkA:
1.7
3jt3B-1dvkA:
1.6		 3jt3A-1dvkA:
17.18
3jt3B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 3jt6A-1dvkA:
1.8
3jt6B-1dvkA:
1.5		 3jt6A-1dvkA:
17.18
3jt6B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 3jt9A-1dvkA:
1.7
3jt9B-1dvkA:
1.5		 3jt9A-1dvkA:
17.18
3jt9B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 3jtaA-1dvkA:
1.7
3jtaB-1dvkA:
1.7		 3jtaA-1dvkA:
17.18
3jtaB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 3jwsA-1dvkA:
1.7
3jwsB-1dvkA:
1.7		 3jwsA-1dvkA:
16.94
3jwsB-1dvkA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 3jwvA-1dvkA:
1.7
3jwvB-1dvkA:
1.6		 3jwvA-1dvkA:
16.94
3jwvB-1dvkA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 3jwvA-1dvkA:
1.7
3jwvB-1dvkA:
1.7		 3jwvA-1dvkA:
16.94
3jwvB-1dvkA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Q_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.45A 3n5qA-1dvkA:
undetectable
3n5qB-1dvkA:
2.3		 3n5qA-1dvkA:
18.14
3n5qB-1dvkA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 3n5vA-1dvkA:
1.8
3n5vB-1dvkA:
1.5		 3n5vA-1dvkA:
17.18
3n5vB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N67_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 3n67A-1dvkA:
1.5
3n67B-1dvkA:
1.8		 3n67A-1dvkA:
18.14
3n67B-1dvkA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 3n6aA-1dvkA:
1.4
3n6aB-1dvkA:
1.8		 3n6aA-1dvkA:
18.14
3n6aB-1dvkA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 3n6eA-1dvkA:
1.2
3n6eB-1dvkA:
0.1		 3n6eA-1dvkA:
18.14
3n6eB-1dvkA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 3n6gA-1dvkA:
1.2
3n6gB-1dvkA:
1.5		 3n6gA-1dvkA:
18.14
3n6gB-1dvkA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 3nleA-1dvkA:
2.4
3nleB-1dvkA:
2.5		 3nleA-1dvkA:
18.14
3nleB-1dvkA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 3nlgA-1dvkA:
1.5
3nlgB-1dvkA:
2.6		 3nlgA-1dvkA:
18.14
3nlgB-1dvkA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 3nlhA-1dvkA:
undetectable
3nlhB-1dvkA:
2.5		 3nlhA-1dvkA:
18.14
3nlhB-1dvkA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 3nlkA-1dvkA:
1.7
3nlkB-1dvkA:
1.7		 3nlkA-1dvkA:
16.94
3nlkB-1dvkA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 3nlnA-1dvkA:
1.7
3nlnB-1dvkA:
1.7		 3nlnA-1dvkA:
16.94
3nlnB-1dvkA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 3nlnA-1dvkA:
1.7
3nlnB-1dvkA:
1.7		 3nlnA-1dvkA:
16.94
3nlnB-1dvkA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.44A 3nloA-1dvkA:
1.7
3nloB-1dvkA:
1.4		 3nloA-1dvkA:
16.94
3nloB-1dvkA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.45A 3nloA-1dvkA:
1.7
3nloB-1dvkA:
1.4		 3nloA-1dvkA:
16.94
3nloB-1dvkA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 3nluA-1dvkA:
1.1
3nluB-1dvkA:
2.4		 3nluA-1dvkA:
18.14
3nluB-1dvkA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 3nlvA-1dvkA:
1.7
3nlvB-1dvkA:
1.7		 3nlvA-1dvkA:
17.18
3nlvB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 3nlwA-1dvkA:
1.8
3nlwB-1dvkA:
1.5		 3nlwA-1dvkA:
17.18
3nlwB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 3nnzA-1dvkA:
1.8
3nnzB-1dvkA:
0.0		 3nnzA-1dvkA:
17.18
3nnzB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_B_H4BB1011_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.46A 3nosA-1dvkA:
2.1
3nosB-1dvkA:
2.0		 3nosA-1dvkA:
17.38
3nosB-1dvkA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 3q99A-1dvkA:
1.7
3q99B-1dvkA:
1.7		 3q99A-1dvkA:
17.18
3q99B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 3rqjA-1dvkA:
1.8
3rqjB-1dvkA:
0.0		 3rqjA-1dvkA:
17.18
3rqjB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 3rqnA-1dvkA:
2.5
3rqnB-1dvkA:
0.0		 3rqnA-1dvkA:
17.18
3rqnB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 3svpA-1dvkA:
1.7
3svpB-1dvkA:
1.5		 3svpA-1dvkA:
17.18
3svpB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 3tymA-1dvkA:
1.8
3tymB-1dvkA:
0.0		 3tymA-1dvkA:
17.18
3tymB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 3tymA-1dvkA:
1.8
3tymB-1dvkA:
0.0		 3tymA-1dvkA:
17.18
3tymB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 3tynA-1dvkA:
1.7
3tynB-1dvkA:
1.7		 3tynA-1dvkA:
17.18
3tynB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 3tyoA-1dvkA:
1.8
3tyoB-1dvkA:
1.6		 3tyoA-1dvkA:
17.18
3tyoB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 3ufoA-1dvkA:
1.7
3ufoB-1dvkA:
1.7		 3ufoA-1dvkA:
17.18
3ufoB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.46A 3ufpA-1dvkA:
1.7
3ufpB-1dvkA:
2.0		 3ufpA-1dvkA:
17.18
3ufpB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 3ufpA-1dvkA:
1.7
3ufpB-1dvkA:
2.0		 3ufpA-1dvkA:
17.18
3ufpB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 3ufqA-1dvkA:
1.7
3ufqB-1dvkA:
1.7		 3ufqA-1dvkA:
17.18
3ufqB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 3ufsA-1dvkA:
1.8
3ufsB-1dvkA:
0.0		 3ufsA-1dvkA:
17.18
3ufsB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 3uftA-1dvkA:
1.8
3uftB-1dvkA:
1.5		 3uftA-1dvkA:
17.18
3uftB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 3ufwA-1dvkA:
1.7
3ufwB-1dvkA:
1.5		 3ufwA-1dvkA:
17.18
3ufwB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 4canA-1dvkA:
1.7
4canB-1dvkA:
1.6		 4canA-1dvkA:
17.18
4canB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.46A 4caoA-1dvkA:
1.7
4caoB-1dvkA:
1.5		 4caoA-1dvkA:
17.18
4caoB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 4caqA-1dvkA:
1.7
4caqB-1dvkA:
1.4		 4caqA-1dvkA:
17.18
4caqB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.46A 4cdtA-1dvkA:
1.7
4cdtB-1dvkA:
1.5		 4cdtA-1dvkA:
17.18
4cdtB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 4cdtA-1dvkA:
1.7
4cdtB-1dvkA:
1.5		 4cdtA-1dvkA:
17.18
4cdtB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.45A 4ctrA-1dvkA:
1.7
4ctrB-1dvkA:
1.5		 4ctrA-1dvkA:
17.18
4ctrB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 4ctrA-1dvkA:
1.7
4ctrB-1dvkA:
1.5		 4ctrA-1dvkA:
17.18
4ctrB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 4cttA-1dvkA:
1.7
4cttB-1dvkA:
1.6		 4cttA-1dvkA:
17.18
4cttB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 4cttA-1dvkA:
1.7
4cttB-1dvkA:
1.6		 4cttA-1dvkA:
17.18
4cttB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 4ctuA-1dvkA:
1.7
4ctuB-1dvkA:
1.4		 4ctuA-1dvkA:
17.18
4ctuB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 4ctzA-1dvkA:
1.2
4ctzB-1dvkA:
0.0		 4ctzA-1dvkA:
17.95
4ctzB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 4d2yA-1dvkA:
1.6
4d2yB-1dvkA:
0.0		 4d2yA-1dvkA:
17.18
4d2yB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 4d2yA-1dvkA:
1.6
4d2yB-1dvkA:
0.0		 4d2yA-1dvkA:
17.18
4d2yB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.45A 4d2zA-1dvkA:
1.7
4d2zB-1dvkA:
0.0		 4d2zA-1dvkA:
17.18
4d2zB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 4d2zA-1dvkA:
1.7
4d2zB-1dvkA:
0.0		 4d2zA-1dvkA:
17.18
4d2zB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 4d30A-1dvkA:
1.7
4d30B-1dvkA:
1.4		 4d30A-1dvkA:
17.18
4d30B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 4d30A-1dvkA:
1.7
4d30B-1dvkA:
1.4		 4d30A-1dvkA:
17.18
4d30B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 4d31A-1dvkA:
1.7
4d31B-1dvkA:
0.0		 4d31A-1dvkA:
17.18
4d31B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.45A 4d31A-1dvkA:
1.7
4d31B-1dvkA:
0.0		 4d31A-1dvkA:
17.18
4d31B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.45A 4d32A-1dvkA:
1.7
4d32B-1dvkA:
1.4		 4d32A-1dvkA:
17.18
4d32B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 4d34A-1dvkA:
undetectable
4d34B-1dvkA:
1.6		 4d34A-1dvkA:
17.95
4d34B-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D35_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 4d35A-1dvkA:
undetectable
4d35B-1dvkA:
1.5		 4d35A-1dvkA:
17.95
4d35B-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 4d36A-1dvkA:
1.6
4d36B-1dvkA:
2.4		 4d36A-1dvkA:
17.95
4d36B-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 4d36A-1dvkA:
1.6
4d36B-1dvkA:
2.4		 4d36A-1dvkA:
17.95
4d36B-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 4d38A-1dvkA:
1.4
4d38B-1dvkA:
1.8		 4d38A-1dvkA:
17.95
4d38B-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 4d39A-1dvkA:
1.6
4d39B-1dvkA:
0.0		 4d39A-1dvkA:
17.95
4d39B-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.45A 4d3aA-1dvkA:
1.5
4d3aB-1dvkA:
0.0		 4d3aA-1dvkA:
17.95
4d3aB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 4d3aA-1dvkA:
1.5
4d3aB-1dvkA:
0.0		 4d3aA-1dvkA:
17.95
4d3aB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 4d3bA-1dvkA:
2.1
4d3bB-1dvkA:
0.0		 4d3bA-1dvkA:
17.18
4d3bB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 LYS A 234
ILE A 237
VAL A 166
LEU A 167
 None
 1.06A 4em2A-1dvkA:
0.0		 4em2A-1dvkA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 4fvwA-1dvkA:
1.8
4fvwB-1dvkA:
1.5		 4fvwA-1dvkA:
17.18
4fvwB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 4jsfA-1dvkA:
1.7
4jsfB-1dvkA:
0.0		 4jsfA-1dvkA:
17.18
4jsfB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 4jsgA-1dvkA:
1.7
4jsgB-1dvkA:
0.0		 4jsgA-1dvkA:
17.18
4jsgB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 4jsgA-1dvkA:
1.7
4jsgB-1dvkA:
0.0		 4jsgA-1dvkA:
17.18
4jsgB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 4jshA-1dvkA:
1.7
4jshB-1dvkA:
1.7		 4jshA-1dvkA:
17.18
4jshB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.43A 4jshA-1dvkA:
1.7
4jshB-1dvkA:
1.7		 4jshA-1dvkA:
17.18
4jshB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 4jsiA-1dvkA:
1.6
4jsiB-1dvkA:
1.6		 4jsiA-1dvkA:
17.18
4jsiB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 4jsiA-1dvkA:
1.6
4jsiB-1dvkA:
1.6		 4jsiA-1dvkA:
17.18
4jsiB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 4jskA-1dvkA:
undetectable
4jskB-1dvkA:
1.5		 4jskA-1dvkA:
17.95
4jskB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 4jskA-1dvkA:
undetectable
4jskB-1dvkA:
1.5		 4jskA-1dvkA:
17.95
4jskB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 4jsmA-1dvkA:
1.2
4jsmB-1dvkA:
1.5		 4jsmA-1dvkA:
17.95
4jsmB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 4k5fA-1dvkA:
1.7
4k5fB-1dvkA:
1.6		 4k5fA-1dvkA:
17.18
4k5fB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 4kchA-1dvkA:
1.7
4kchB-1dvkA:
1.7		 4kchA-1dvkA:
17.18
4kchB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 4kchA-1dvkA:
1.7
4kchB-1dvkA:
1.7		 4kchA-1dvkA:
17.18
4kchB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 4kciA-1dvkA:
1.7
4kciB-1dvkA:
1.5		 4kciA-1dvkA:
17.18
4kciB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 4kciA-1dvkA:
1.7
4kciB-1dvkA:
1.5		 4kciA-1dvkA:
17.18
4kciB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 4kcjA-1dvkA:
1.7
4kcjB-1dvkA:
1.7		 4kcjA-1dvkA:
17.18
4kcjB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 4uchA-1dvkA:
1.6
4uchB-1dvkA:
0.0		 4uchA-1dvkA:
17.40
4uchB-1dvkA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 8 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 4uchA-1dvkA:
1.6
4uchB-1dvkA:
0.0		 4uchA-1dvkA:
17.40
4uchB-1dvkA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 4ugzA-1dvkA:
1.7
4ugzB-1dvkA:
0.0		 4ugzA-1dvkA:
17.18
4ugzB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 4uh0A-1dvkA:
1.8
4uh0B-1dvkA:
1.5		 4uh0A-1dvkA:
17.18
4uh0B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 4uh0A-1dvkA:
1.8
4uh0B-1dvkA:
1.5		 4uh0A-1dvkA:
17.18
4uh0B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 4uh1A-1dvkA:
1.7
4uh1B-1dvkA:
1.5		 4uh1A-1dvkA:
17.18
4uh1B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 4uh1A-1dvkA:
1.7
4uh1B-1dvkA:
1.5		 4uh1A-1dvkA:
17.18
4uh1B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 4uh2A-1dvkA:
1.7
4uh2B-1dvkA:
1.6		 4uh2A-1dvkA:
17.18
4uh2B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 4uh4A-1dvkA:
1.7
4uh4B-1dvkA:
1.5		 4uh4A-1dvkA:
17.18
4uh4B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 4uh5A-1dvkA:
1.5
4uh5B-1dvkA:
0.0		 4uh5A-1dvkA:
17.06
4uh5B-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 4uh6A-1dvkA:
1.6
4uh6B-1dvkA:
2.5		 4uh6A-1dvkA:
17.06
4uh6B-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 4uh7A-1dvkA:
undetectable
4uh7B-1dvkA:
1.6		 4uh7A-1dvkA:
17.95
4uh7B-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 4uh8A-1dvkA:
undetectable
4uh8B-1dvkA:
0.0		 4uh8A-1dvkA:
17.95
4uh8B-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 4uh8A-1dvkA:
undetectable
4uh8B-1dvkA:
0.0		 4uh8A-1dvkA:
17.95
4uh8B-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 4uh9A-1dvkA:
2.3
4uh9B-1dvkA:
1.8		 4uh9A-1dvkA:
17.95
4uh9B-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 4uh9A-1dvkA:
2.3
4uh9B-1dvkA:
1.8		 4uh9A-1dvkA:
17.95
4uh9B-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 4upnA-1dvkA:
1.7
4upnB-1dvkA:
1.4		 4upnA-1dvkA:
17.18
4upnB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 4v3uA-1dvkA:
1.3
4v3uB-1dvkA:
1.7		 4v3uA-1dvkA:
16.86
4v3uB-1dvkA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 4v3uC-1dvkA:
1.1
4v3uD-1dvkA:
1.6		 4v3uC-1dvkA:
16.86
4v3uD-1dvkA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.44A 4v3wA-1dvkA:
undetectable
4v3wB-1dvkA:
1.4		 4v3wA-1dvkA:
17.18
4v3wB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 4v3xA-1dvkA:
1.6
4v3xB-1dvkA:
1.4		 4v3xA-1dvkA:
17.18
4v3xB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 4v3yA-1dvkA:
1.7
4v3yB-1dvkA:
1.6		 4v3yA-1dvkA:
17.18
4v3yB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.46A 4v3zA-1dvkA:
1.7
4v3zB-1dvkA:
1.4		 4v3zA-1dvkA:
17.18
4v3zB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.39A 4v3zA-1dvkA:
1.7
4v3zB-1dvkA:
1.4		 4v3zA-1dvkA:
17.18
4v3zB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.46A 5ad4A-1dvkA:
1.6
5ad4B-1dvkA:
1.4		 5ad4A-1dvkA:
17.18
5ad4B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.45A 5ad4A-1dvkA:
1.6
5ad4B-1dvkA:
1.4		 5ad4A-1dvkA:
17.18
5ad4B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.45A 5ad5A-1dvkA:
1.6
5ad5B-1dvkA:
1.4		 5ad5A-1dvkA:
17.18
5ad5B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 5ad5A-1dvkA:
1.6
5ad5B-1dvkA:
1.4		 5ad5A-1dvkA:
17.18
5ad5B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.45A 5ad6A-1dvkA:
1.7
5ad6B-1dvkA:
1.6		 5ad6A-1dvkA:
17.18
5ad6B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.44A 5ad6A-1dvkA:
1.7
5ad6B-1dvkA:
1.6		 5ad6A-1dvkA:
17.18
5ad6B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 5ad7A-1dvkA:
1.7
5ad7B-1dvkA:
1.7		 5ad7A-1dvkA:
17.18
5ad7B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 5ad8A-1dvkA:
1.7
5ad8B-1dvkA:
1.7		 5ad8A-1dvkA:
17.18
5ad8B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.44A 5ad9A-1dvkA:
undetectable
5ad9B-1dvkA:
undetectable		 5ad9A-1dvkA:
17.18
5ad9B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.42A 5ad9A-1dvkA:
1.6
5ad9B-1dvkA:
1.4		 5ad9A-1dvkA:
17.18
5ad9B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 5adaA-1dvkA:
1.7
5adaB-1dvkA:
1.6		 5adaA-1dvkA:
17.18
5adaB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 5adaA-1dvkA:
1.7
5adaB-1dvkA:
1.6		 5adaA-1dvkA:
17.18
5adaB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.40A 5adbA-1dvkA:
1.7
5adbB-1dvkA:
1.4		 5adbA-1dvkA:
17.18
5adbB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 5adcA-1dvkA:
1.6
5adcB-1dvkA:
0.0		 5adcA-1dvkA:
17.18
5adcB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.43A 5adcA-1dvkA:
1.6
5adcB-1dvkA:
0.0		 5adcA-1dvkA:
17.18
5adcB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 5adgA-1dvkA:
1.6
5adgB-1dvkA:
0.0		 5adgA-1dvkA:
17.06
5adgB-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 5adiA-1dvkA:
1.6
5adiB-1dvkA:
2.1		 5adiA-1dvkA:
17.06
5adiB-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 5adjA-1dvkA:
1.5
5adjB-1dvkA:
1.6		 5adjA-1dvkA:
17.95
5adjB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 5adkA-1dvkA:
1.3
5adkB-1dvkA:
0.0		 5adkA-1dvkA:
17.95
5adkB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.43A 5adlA-1dvkA:
1.2
5adlB-1dvkA:
2.4		 5adlA-1dvkA:
17.95
5adlB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 5admA-1dvkA:
1.5
5admB-1dvkA:
2.7		 5admA-1dvkA:
17.95
5admB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 5admA-1dvkA:
1.5
5admB-1dvkA:
2.7		 5admA-1dvkA:
17.95
5admB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 5adnA-1dvkA:
1.5
5adnB-1dvkA:
undetectable		 5adnA-1dvkA:
17.95
5adnB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 5agkA-1dvkA:
1.7
5agkB-1dvkA:
2.1		 5agkA-1dvkA:
17.18
5agkB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 5agkA-1dvkA:
1.7
5agkB-1dvkA:
2.1		 5agkA-1dvkA:
17.18
5agkB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 5agnA-1dvkA:
1.7
5agnB-1dvkA:
0.0		 5agnA-1dvkA:
17.18
5agnB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 5agoA-1dvkA:
1.7
5agoB-1dvkA:
1.4		 5agoA-1dvkA:
17.18
5agoB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 5agoA-1dvkA:
1.7
5agoB-1dvkA:
1.4		 5agoA-1dvkA:
17.18
5agoB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 5fj2A-1dvkA:
1.4
5fj2B-1dvkA:
0.0		 5fj2A-1dvkA:
17.95
5fj2B-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 5fvpA-1dvkA:
2.2
5fvpB-1dvkA:
1.4		 5fvpA-1dvkA:
17.18
5fvpB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.40A 5fvpA-1dvkA:
2.2
5fvpB-1dvkA:
1.4		 5fvpA-1dvkA:
17.18
5fvpB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.46A 5fvuA-1dvkA:
1.6
5fvuB-1dvkA:
2.1		 5fvuA-1dvkA:
17.06
5fvuB-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 5fvvA-1dvkA:
1.6
5fvvB-1dvkA:
2.4		 5fvvA-1dvkA:
17.06
5fvvB-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 5fvvA-1dvkA:
1.6
5fvvB-1dvkA:
2.4		 5fvvA-1dvkA:
17.06
5fvvB-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 5fvwA-1dvkA:
1.4
5fvwB-1dvkA:
2.4		 5fvwA-1dvkA:
17.06
5fvwB-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 5fvzA-1dvkA:
1.5
5fvzB-1dvkA:
2.3		 5fvzA-1dvkA:
17.95
5fvzB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 5g0oA-1dvkA:
1.4
5g0oB-1dvkA:
1.7		 5g0oA-1dvkA:
17.18
5g0oB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 5unrA-1dvkA:
1.7
5unrB-1dvkA:
0.0		 5unrA-1dvkA:
17.18
5unrB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 5untA-1dvkA:
1.7
5untB-1dvkA:
1.4		 5untA-1dvkA:
17.18
5untB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 5untA-1dvkA:
1.7
5untB-1dvkA:
1.4		 5untA-1dvkA:
17.18
5untB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 5unuA-1dvkA:
1.5
5unuB-1dvkA:
1.6		 5unuA-1dvkA:
17.18
5unuB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.42A 5unuA-1dvkA:
1.5
5unuB-1dvkA:
1.6		 5unuA-1dvkA:
17.18
5unuB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 5unwA-1dvkA:
2.4
5unwB-1dvkA:
1.6		 5unwA-1dvkA:
17.18
5unwB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 5unwA-1dvkA:
2.4
5unwB-1dvkA:
1.6		 5unwA-1dvkA:
17.18
5unwB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 5unxA-1dvkA:
2.5
5unxB-1dvkA:
1.4		 5unxA-1dvkA:
17.18
5unxB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.41A 5unxA-1dvkA:
2.5
5unxB-1dvkA:
1.4		 5unxA-1dvkA:
17.18
5unxB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 5unyA-1dvkA:
0.0
5unyB-1dvkA:
1.6		 5unyA-1dvkA:
17.18
5unyB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 5unyA-1dvkA:
0.0
5unyB-1dvkA:
1.6		 5unyA-1dvkA:
17.18
5unyB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 5unzA-1dvkA:
1.7
5unzB-1dvkA:
1.4		 5unzA-1dvkA:
17.18
5unzB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.45A 5uo0A-1dvkA:
2.3
5uo0B-1dvkA:
undetectable		 5uo0A-1dvkA:
17.18
5uo0B-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.44A 5uo3A-1dvkA:
1.3
5uo3B-1dvkA:
1.5		 5uo3A-1dvkA:
17.06
5uo3B-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 5uo3A-1dvkA:
1.3
5uo3B-1dvkA:
1.5		 5uo3A-1dvkA:
17.06
5uo3B-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.45A 5uo4A-1dvkA:
1.5
5uo4B-1dvkA:
0.0		 5uo4A-1dvkA:
17.06
5uo4B-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 5uo5A-1dvkA:
1.5
5uo5B-1dvkA:
0.1		 5uo5A-1dvkA:
17.06
5uo5B-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.46A 5uo7A-1dvkA:
1.6
5uo7B-1dvkA:
1.4		 5uo7A-1dvkA:
17.06
5uo7B-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 5uo8A-1dvkA:
0.0
5uo8B-1dvkA:
0.0		 5uo8A-1dvkA:
16.48
5uo8B-1dvkA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.43A 5uo9A-1dvkA:
0.0
5uo9B-1dvkA:
0.1		 5uo9A-1dvkA:
16.48
5uo9B-1dvkA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.44A 5uo9C-1dvkA:
0.0
5uo9D-1dvkA:
0.0		 5uo9C-1dvkA:
16.48
5uo9D-1dvkA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 147
LEU A 121
ARG A 235
LEU A 236
ALA A 142
 None
 1.21A 5v0vA-1dvkA:
undetectable		 5v0vA-1dvkA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.48A 5vuiA-1dvkA:
2.3
5vuiB-1dvkA:
1.4		 5vuiA-1dvkA:
17.18
5vuiB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 5vuiA-1dvkA:
2.3
5vuiB-1dvkA:
1.4		 5vuiA-1dvkA:
17.18
5vuiB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.45A 5vujA-1dvkA:
1.7
5vujB-1dvkA:
1.5		 5vujA-1dvkA:
17.18
5vujB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 5vukA-1dvkA:
1.7
5vukB-1dvkA:
1.4		 5vukA-1dvkA:
17.18
5vukB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.46A 5vukA-1dvkA:
1.7
5vukB-1dvkA:
1.4		 5vukA-1dvkA:
17.18
5vukB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 5vumA-1dvkA:
1.7
5vumB-1dvkA:
1.4		 5vumA-1dvkA:
17.18
5vumB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 5vunA-1dvkA:
1.7
5vunB-1dvkA:
0.0		 5vunA-1dvkA:
17.18
5vunB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 5vuoA-1dvkA:
2.1
5vuoB-1dvkA:
0.0		 5vuoA-1dvkA:
17.18
5vuoB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 5vuqA-1dvkA:
1.7
5vuqB-1dvkA:
0.0		 5vuqA-1dvkA:
17.18
5vuqB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.45A 5vurA-1dvkA:
1.7
5vurB-1dvkA:
1.9		 5vurA-1dvkA:
17.18
5vurB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 5vusA-1dvkA:
2.5
5vusB-1dvkA:
1.4		 5vusA-1dvkA:
17.18
5vusB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 5vusA-1dvkA:
2.5
5vusB-1dvkA:
1.4		 5vusA-1dvkA:
17.18
5vusB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 5vutA-1dvkA:
1.6
5vutB-1dvkA:
0.0		 5vutA-1dvkA:
17.18
5vutB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 5vuuA-1dvkA:
0.0
5vuuB-1dvkA:
1.7		 5vuuA-1dvkA:
17.18
5vuuB-1dvkA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 5vuxA-1dvkA:
1.6
5vuxB-1dvkA:
1.6		 5vuxA-1dvkA:
17.06
5vuxB-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 5vuyA-1dvkA:
1.4
5vuyB-1dvkA:
0.0		 5vuyA-1dvkA:
17.06
5vuyB-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.50A 5vuzA-1dvkA:
1.6
5vuzB-1dvkA:
0.0		 5vuzA-1dvkA:
17.06
5vuzB-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 5vv2A-1dvkA:
1.4
5vv2B-1dvkA:
2.1		 5vv2A-1dvkA:
17.06
5vv2B-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.49A 5vv2A-1dvkA:
1.4
5vv2B-1dvkA:
2.1		 5vv2A-1dvkA:
17.06
5vv2B-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 5vv3A-1dvkA:
1.3
5vv3B-1dvkA:
1.7		 5vv3A-1dvkA:
17.06
5vv3B-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 5vv5A-1dvkA:
1.4
5vv5B-1dvkA:
2.0		 5vv5A-1dvkA:
17.06
5vv5B-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.45A 5vv5A-1dvkA:
1.4
5vv5B-1dvkA:
2.0		 5vv5A-1dvkA:
17.06
5vv5B-1dvkA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.45A 5vvbA-1dvkA:
0.0
5vvbB-1dvkA:
0.0		 5vvbA-1dvkA:
16.48
5vvbB-1dvkA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.46A 5vvbA-1dvkA:
0.0
5vvbB-1dvkA:
0.0		 5vvbA-1dvkA:
16.48
5vvbB-1dvkA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.46A 5vvcC-1dvkA:
0.0
5vvcD-1dvkA:
0.0		 5vvcC-1dvkA:
16.48
5vvcD-1dvkA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.41A 5vvdC-1dvkA:
undetectable
5vvdD-1dvkA:
0.4		 5vvdC-1dvkA:
16.48
5vvdD-1dvkA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 5vvgA-1dvkA:
0.9
5vvgB-1dvkA:
undetectable		 5vvgA-1dvkA:
17.95
5vvgB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 5vvnA-1dvkA:
1.2
5vvnB-1dvkA:
undetectable		 5vvnA-1dvkA:
17.95
5vvnB-1dvkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 6auqA-1dvkA:
1.7
6auqB-1dvkA:
1.5		 6auqA-1dvkA:
18.50
6auqB-1dvkA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.45A 6auqA-1dvkA:
1.7
6auqB-1dvkA:
1.5		 6auqA-1dvkA:
18.50
6auqB-1dvkA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.46A 6auuA-1dvkA:
2.4
6auuB-1dvkA:
0.0		 6auuA-1dvkA:
18.50
6auuB-1dvkA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.48A 6auwA-1dvkA:
1.7
6auwB-1dvkA:
0.0		 6auwA-1dvkA:
18.50
6auwB-1dvkA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.47A 6auxA-1dvkA:
1.7
6auxB-1dvkA:
1.4		 6auxA-1dvkA:
18.50
6auxB-1dvkA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.47A 6auyA-1dvkA:
1.4
6auyB-1dvkA:
2.1		 6auyA-1dvkA:
19.08
6auyB-1dvkA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 6auzA-1dvkA:
1.4
6auzB-1dvkA:
2.4		 6auzA-1dvkA:
19.08
6auzB-1dvkA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 6av0A-1dvkA:
1.6
6av0B-1dvkA:
2.2		 6av0A-1dvkA:
19.08
6av0B-1dvkA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 6av1A-1dvkA:
1.5
6av1B-1dvkA:
0.0		 6av1A-1dvkA:
19.08
6av1B-1dvkA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.44A 6av1A-1dvkA:
1.5
6av1B-1dvkA:
0.0		 6av1A-1dvkA:
19.08
6av1B-1dvkA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.46A 6av2A-1dvkA:
1.6
6av2B-1dvkA:
1.5		 6av2A-1dvkA:
19.08
6av2B-1dvkA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.49A 6av4A-1dvkA:
1.6
6av4B-1dvkA:
0.0		 6av4A-1dvkA:
19.08
6av4B-1dvkA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.50A 6av5A-1dvkA:
1.6
6av5B-1dvkA:
0.0		 6av5A-1dvkA:
19.08
6av5B-1dvkA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB503_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.41A 6av6A-1dvkA:
undetectable
6av6B-1dvkA:
0.0		 6av6A-1dvkA:
21.60
6av6B-1dvkA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 242
PHE A 239
GLU A 241
ARG A 123
 None
 1.43A 6av6C-1dvkA:
0.0
6av6D-1dvkA:
0.0		 6av6C-1dvkA:
21.60
6av6D-1dvkA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1dvk PRP18
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 123
TRP A 242
PHE A 239
GLU A 241
 None
 1.45A 6av7C-1dvkA:
0.0
6av7D-1dvkA:
0.0		 6av7C-1dvkA:
21.60
6av7D-1dvkA:
21.60