SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dvp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_E_SAME301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	1dvp	HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE (Drosophila melanogaster)	3 / 3	SER A 5 ASP A 31 CYH A 73	None	1.12A	2br4E-1dvpA: undetectable	2br4E-1dvpA: 19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DR2_A_PARA1609_1 (16S RRNA 30S RIBOSOMAL PROTEIN S9 30S RIBOSOMAL PROTEIN S10)	1dvp	HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE (Drosophila melanogaster)	3 / 3	TYR A 61 ARG A 18 SER A 15	None	1.11A	4dr2I-1dvpA: 0.0 4dr2J-1dvpA: undetectable	4dr2I-1dvpA: 19.64 4dr2J-1dvpA: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UTU_F_ADNF503_2 (ADENOSYLHOMOCYSTEINA SE)	1dvp	HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE (Drosophila melanogaster)	4 / 4	GLU A 88 THR A 129 GLU A 95 HIS A 99	None	1.32A	5utuF-1dvpA: 0.0	5utuF-1dvpA: 17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDX_C_CHDC308_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART)	1dvp	HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE (Drosophila melanogaster)	4 / 5	LEU A 94 PHE A 90 LEU A 133 PHE A 140	None	1.22A	5xdxC-1dvpA: 0.5 5xdxJ-1dvpA: 0.0	5xdxC-1dvpA: 22.06 5xdxJ-1dvpA: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDX_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART)	1dvp	HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE (Drosophila melanogaster)	4 / 5	LEU A 94 PHE A 90 LEU A 133 PHE A 140	None	1.27A	5xdxP-1dvpA: 0.5 5xdxW-1dvpA: 0.0	5xdxP-1dvpA: 22.06 5xdxW-1dvpA: 15.58

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BR4_E_SAME301_1","CEPHALOSPORIN HYDROXYLASE CMCI","1dvp","HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE","Drosophila melanogaster",3,"SER A   5;ASP A  31;CYH A  73","None","1.12A","2br4E-1dvpA:undetectable","2br4E-1dvpA:19.50"],["4DR2_A_PARA1609_1","16S RRNA;30S RIBOSOMAL PROTEIN S9;30S RIBOSOMAL PROTEIN S10","1dvp","HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE","Drosophila melanogaster",3,"TYR A  61;ARG A  18;SER A  15","None","1.11A","4dr2I-1dvpA:0.0;4dr2J-1dvpA:undetectable","4dr2I-1dvpA:19.64;4dr2J-1dvpA:20.27"],["5UTU_F_ADNF503_2","ADENOSYLHOMOCYSTEINASE","1dvp","HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE","Drosophila melanogaster",4,"GLU A  88;THR A 129;GLU A  95;HIS A  99","None","1.32A","5utuF-1dvpA:0.0","5utuF-1dvpA:17.73"],["5XDX_C_CHDC308_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART","1dvp","HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE","Drosophila melanogaster",4,"LEU A  94;PHE A  90;LEU A 133;PHE A 140","None","1.22A","5xdxC-1dvpA:0.5;5xdxJ-1dvpA:0.0","5xdxC-1dvpA:22.06;5xdxJ-1dvpA:15.58"],["5XDX_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART","1dvp","HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE","Drosophila melanogaster",4,"LEU A  94;PHE A  90;LEU A 133;PHE A 140","None","1.27A","5xdxP-1dvpA:0.5;5xdxW-1dvpA:0.0","5xdxP-1dvpA:22.06;5xdxW-1dvpA:15.58"]]