SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dwu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 1dwu RIBOSOMAL PROTEIN L1
(Methanothermococ
cus
thermolithotroph
icus) 		3 / 4 LYS A  65
ALA A  64
MET A 111
 None
 1.05A 1hk3A-1dwuA:
undetectable		 1hk3A-1dwuA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 1dwu RIBOSOMAL PROTEIN L1
(Methanothermococ
cus
thermolithotroph
icus) 		5 / 12 GLY A 127
GLY A 124
LEU A 119
PHE A 105
ASN A 100
 None
 1.17A 1qzzA-1dwuA:
undetectable		 1qzzA-1dwuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1dwu RIBOSOMAL PROTEIN L1
(Methanothermococ
cus
thermolithotroph
icus) 		4 / 7 THR A 154
LEU A  32
VAL A 196
ILE A 181
 None
 0.96A 1t87B-1dwuA:
undetectable		 1t87B-1dwuA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 1dwu RIBOSOMAL PROTEIN L1
(Methanothermococ
cus
thermolithotroph
icus) 		5 / 12 GLY A 127
GLY A 124
LEU A 119
PHE A 105
ASN A 100
 None
 1.17A 1xdsB-1dwuA:
undetectable		 1xdsB-1dwuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 1dwu RIBOSOMAL PROTEIN L1
(Methanothermococ
cus
thermolithotroph
icus) 		4 / 7 PRO A 113
LYS A 117
GLY A 120
PRO A 121
 None
 1.36A 3ucbB-1dwuA:
undetectable		 3ucbB-1dwuA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 1dwu RIBOSOMAL PROTEIN L1
(Methanothermococ
cus
thermolithotroph
icus) 		5 / 12 LEU A 119
GLU A  84
ALA A  95
GLU A  87
ASN A  91
 None
 1.49A 4cpzD-1dwuA:
undetectable		 4cpzD-1dwuA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 1dwu RIBOSOMAL PROTEIN L1
(Methanothermococ
cus
thermolithotroph
icus) 		5 / 9 ARG A 126
LEU A 123
LEU A  85
ILE A  80
ALA A  95
 None
 1.46A 4z69A-1dwuA:
0.3		 4z69A-1dwuA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_I_DIFI1006_1
(SERUM ALBUMIN)		 1dwu RIBOSOMAL PROTEIN L1
(Methanothermococ
cus
thermolithotroph
icus) 		5 / 10 ARG A 126
PHE A 105
LEU A  85
ILE A  80
ALA A  95
 None
 1.46A 4z69I-1dwuA:
undetectable		 4z69I-1dwuA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 1dwu RIBOSOMAL PROTEIN L1
(Methanothermococ
cus
thermolithotroph
icus) 		4 / 8 LEU A 151
VAL A  48
LEU A 163
ILE A 181
 None
 0.96A 5v0vA-1dwuA:
undetectable		 5v0vA-1dwuA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1dwu RIBOSOMAL PROTEIN L1
(Methanothermococ
cus
thermolithotroph
icus) 		5 / 10 VAL A 122
GLY A 120
GLY A 116
LEU A  88
ALA A  95
 None
 0.96A 5vm8B-1dwuA:
3.0		 5vm8B-1dwuA:
21.62