SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dxj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		3 / 3 ALA A 153
THR A  65
PHE A  42
 None
 0.67A 2c6nB-1dxjA:
0.0		 2c6nB-1dxjA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		4 / 6 PHE A 217
ARG A 214
GLY A  84
THR A  70
 None
 1.12A 2f7fA-1dxjA:
undetectable		 2f7fA-1dxjA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		3 / 3 TYR A 124
VAL A 142
THR A 119
 None
 0.57A 2ygnA-1dxjA:
undetectable		 2ygnA-1dxjA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		5 / 12 VAL A  88
PHE A  61
LEU A  62
ALA A  34
SER A 149
 None
 1.32A 3apvA-1dxjA:
undetectable		 3apvA-1dxjA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		5 / 12 VAL A  88
PHE A  61
LEU A  62
ALA A  34
SER A 149
 None
 1.36A 3apvB-1dxjA:
undetectable		 3apvB-1dxjA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		5 / 12 PHE A  29
VAL A  88
PHE A  61
ALA A  34
SER A 149
 None
 1.45A 3apwA-1dxjA:
undetectable		 3apwA-1dxjA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		5 / 12 SER A  66
TYR A  85
VAL A   3
PHE A  45
PHE A  12
 None
 1.44A 3u9fB-1dxjA:
undetectable
3u9fC-1dxjA:
undetectable		 3u9fB-1dxjA:
21.13
3u9fC-1dxjA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		5 / 12 PHE A  12
SER A  66
TYR A  85
VAL A   3
PHE A  45
 None
 1.44A 3u9fJ-1dxjA:
undetectable
3u9fL-1dxjA:
undetectable		 3u9fJ-1dxjA:
21.13
3u9fL-1dxjA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_M_CLMM221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		5 / 10 SER A  66
TYR A  85
VAL A   3
PHE A  45
PHE A  12
 None
 1.40A 3u9fM-1dxjA:
undetectable
3u9fN-1dxjA:
undetectable		 3u9fM-1dxjA:
21.13
3u9fN-1dxjA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		5 / 11 SER A  66
TYR A  85
VAL A   3
PHE A  45
PHE A  12
 None
 1.49A 3u9fN-1dxjA:
undetectable
3u9fO-1dxjA:
undetectable		 3u9fN-1dxjA:
21.13
3u9fO-1dxjA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_O_CLMO221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		5 / 11 PHE A  12
SER A  66
TYR A  85
VAL A   3
PHE A  45
 None
 1.43A 3u9fM-1dxjA:
undetectable
3u9fO-1dxjA:
undetectable		 3u9fM-1dxjA:
21.13
3u9fO-1dxjA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_B_ACTB502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		4 / 5 GLU A  57
ARG A 174
THR A 172
ASP A 169
 None
 1.49A 4e7cA-1dxjA:
undetectable
4e7cB-1dxjA:
0.0		 4e7cA-1dxjA:
20.57
4e7cB-1dxjA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		5 / 11 ASP A 213
TYR A 221
TYR A  81
GLY A  71
GLY A  79
 None
 1.27A 4mm9A-1dxjA:
undetectable		 4mm9A-1dxjA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		3 / 3 SER A 109
TYR A  97
TYR A 110
 None
 0.86A 5lakA-1dxjA:
undetectable
5lakI-1dxjA:
undetectable		 5lakA-1dxjA:
18.96
5lakI-1dxjA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		4 / 7 PHE A  42
ALA A 130
GLY A 128
TYR A 124
 None
 0.71A 5uxdA-1dxjA:
undetectable		 5uxdA-1dxjA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 1dxj CLASS II CHITINASE
(Canavalia
ensiformis) 		3 / 3 ARG A 144
ARG A 113
ASP A 140
 None
 0.90A 6d8pA-1dxjA:
undetectable		 6d8pA-1dxjA:
16.60