SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dy2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 1dy2 COLLAGEN ALPHA1(XV)
CHAIN
(Mus
musculus) 		4 / 4 THR A 182
GLY A 177
ASP A 176
ALA A  90
 None
 1.25A 1sg9A-1dy2A:
undetectable		 1sg9A-1dy2A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1dy2 COLLAGEN ALPHA1(XV)
CHAIN
(Mus
musculus) 		4 / 5 TRP A 155
GLY A 164
GLY A 163
PHE A 121
 None
 1.06A 2qr2A-1dy2A:
0.0
2qr2B-1dy2A:
0.0		 2qr2A-1dy2A:
22.05
2qr2B-1dy2A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 1dy2 COLLAGEN ALPHA1(XV)
CHAIN
(Mus
musculus) 		3 / 3 SER A 123
TYR A 206
HIS A 193
 None
 0.80A 2r2vD-1dy2A:
undetectable		 2r2vD-1dy2A:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1dy2 COLLAGEN ALPHA1(XV)
CHAIN
(Mus
musculus) 		4 / 6 GLN A 165
PHE A 166
PHE A 152
PHE A 159
 None
 0.95A 3ablP-1dy2A:
undetectable
3ablW-1dy2A:
undetectable		 3ablP-1dy2A:
22.82
3ablW-1dy2A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1dy2 COLLAGEN ALPHA1(XV)
CHAIN
(Mus
musculus) 		4 / 8 PHE A 106
THR A 117
LEU A 115
ALA A 109
 None
 0.95A 3ax7A-1dy2A:
0.0		 3ax7A-1dy2A:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1dy2 COLLAGEN ALPHA1(XV)
CHAIN
(Mus
musculus) 		4 / 8 PHE A 106
THR A 117
LEU A 115
ALA A 109
 None
 0.96A 3ns1L-1dy2A:
0.0		 3ns1L-1dy2A:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1dy2 COLLAGEN ALPHA1(XV)
CHAIN
(Mus
musculus) 		4 / 7 PHE A 106
THR A 117
LEU A 115
ALA A 109
 None
 0.96A 3uniA-1dy2A:
0.1		 3uniA-1dy2A:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRI_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 1dy2 COLLAGEN ALPHA1(XV)
CHAIN
(Mus
musculus) 		5 / 10 LEU A 122
SER A 124
ARG A 201
THR A 212
ASP A  98
 None
 1.47A 4driB-1dy2A:
undetectable		 4driB-1dy2A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1dy2 COLLAGEN ALPHA1(XV)
CHAIN
(Mus
musculus) 		4 / 7 ASN A 196
GLY A 199
VAL A 200
PHE A 139
 None
 0.75A 4fglC-1dy2A:
undetectable		 4fglC-1dy2A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 1dy2 COLLAGEN ALPHA1(XV)
CHAIN
(Mus
musculus) 		4 / 8 SER A 123
LEU A 129
PHE A 159
GLN A 232
 None
 1.10A 4j7uD-1dy2A:
undetectable		 4j7uD-1dy2A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1dy2 COLLAGEN ALPHA1(XV)
CHAIN
(Mus
musculus) 		5 / 9 ILE A 246
VAL A 150
LEU A 151
ILE A 170
PHE A 121
 None
 1.34A 4r38C-1dy2A:
undetectable		 4r38C-1dy2A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1dy2 COLLAGEN ALPHA1(XV)
CHAIN
(Mus
musculus) 		5 / 8 ILE A 246
VAL A 150
LEU A 151
ILE A 170
PHE A 121
 None
 1.34A 4r38D-1dy2A:
undetectable		 4r38D-1dy2A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1dy2 COLLAGEN ALPHA1(XV)
CHAIN
(Mus
musculus) 		4 / 6 GLN A 165
PHE A 166
PHE A 152
PHE A 159
 None
 0.92A 5b1bC-1dy2A:
undetectable
5b1bJ-1dy2A:
0.0		 5b1bC-1dy2A:
22.82
5b1bJ-1dy2A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 1dy2 COLLAGEN ALPHA1(XV)
CHAIN
(Mus
musculus) 		4 / 5 LEU A 241
LEU A 244
LEU A 224
HIS A 193
 None
 1.00A 5gtrA-1dy2A:
undetectable		 5gtrA-1dy2A:
22.04