SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dyp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DY4_A_SNPA437_1 (EXOGLUCANASE 1)	1dyp	KAPPA-CARRAGEENASE (Pseudoalteromona s carrageenovora)	5 / 12	ALA A 142 TYR A 64 GLU A 163 ASP A 165 GLU A 168	None None None None CL A1307 ( 4.3A)	1.15A	1dy4A-1dypA: 11.1	1dy4A-1dypA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MAA_B_DMEB996_1 (ACETYLCHOLINESTERASE)	1dyp	KAPPA-CARRAGEENASE (Pseudoalteromona s carrageenovora)	4 / 6	TYR A 233 GLU A 37 ILE A 230 GLY A 240	None	1.17A	1maaB-1dypA: undetectable 1maaD-1dypA: undetectable	1maaB-1dypA: 19.52 1maaD-1dypA: 19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OH1_C_9UQC202_0 (CEREBLON ISOFORM 4)	1dyp	KAPPA-CARRAGEENASE (Pseudoalteromona s carrageenovora)	4 / 8	ASN A 204 PRO A 197 GLU A 168 TRP A 232	None CL A1307 (-4.6A) CL A1307 ( 4.3A) None	1.15A	5oh1C-1dypA: undetectable	5oh1C-1dypA: 17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA824_0 (GEPHYRIN)	1dyp	KAPPA-CARRAGEENASE (Pseudoalteromona s carrageenovora)	4 / 4	LEU A 169 ASP A 213 PRO A 214 ARG A 215	None	1.10A	6fgdA-1dypA: undetectable	6fgdA-1dypA: 20.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DY4_A_SNPA437_1","EXOGLUCANASE 1","1dyp","KAPPA-CARRAGEENASE","Pseudoalteromonas carrageenovora",5,"ALA A 142;TYR A  64;GLU A 163;ASP A 165;GLU A 168","None;None;None;None; CL A1307 ( 4.3A)","1.15A","1dy4A-1dypA:11.1","1dy4A-1dypA:20.85"],["1MAA_B_DMEB996_1","ACETYLCHOLINESTERASE;ACETYLCHOLINESTERASE","1dyp","KAPPA-CARRAGEENASE","Pseudoalteromonas carrageenovora",4,"TYR A 233;GLU A  37;ILE A 230;GLY A 240","None","1.17A","1maaB-1dypA:undetectable;1maaD-1dypA:undetectable","1maaB-1dypA:19.52;1maaD-1dypA:19.52"],["5OH1_C_9UQC202_0","CEREBLON ISOFORM 4","1dyp","KAPPA-CARRAGEENASE","Pseudoalteromonas carrageenovora",4,"ASN A 204;PRO A 197;GLU A 168;TRP A 232","None; CL A1307 (-4.6A); CL A1307 ( 4.3A);None","1.15A","5oh1C-1dypA:undetectable","5oh1C-1dypA:17.49"],["6FGD_A_ACTA824_0","GEPHYRIN","1dyp","KAPPA-CARRAGEENASE","Pseudoalteromonas carrageenovora",4,"LEU A 169;ASP A 213;PRO A 214;ARG A 215","None","1.10A","6fgdA-1dypA:undetectable","6fgdA-1dypA:20.77"]]