SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dzb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KCE_B_D16B568_1 (THYMIDYLATE SYNTHASE)	1dzb	SCFV FRAGMENT 1F9 (Mus musculus)	5 / 12	HIS A 35 ASP A 228 GLY A 292 TYR A 271 ALA A 251	None	1.23A	2kceB-1dzbA: 0.0	2kceB-1dzbA: 21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E0F_A_RBFA301_2 (RIBOFLAVIN SYNTHASE SUBUNIT ALPHA)	1dzb	SCFV FRAGMENT 1F9 (Mus musculus)	3 / 3	LYS A 239 THR A 284 ILE A 275	None	0.78A	4e0fB-1dzbA: 1.0	4e0fB-1dzbA: 23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P7N_A_GCSA702_1 (POLY-BETA-1,6-N-ACET YL-D-GLUCOSAMINE N-DEACETYLASE)	1dzb	SCFV FRAGMENT 1F9 (Mus musculus)	3 / 3	ASP A 104 TYR A 249 TRP A 99	None	1.33A	4p7nA-1dzbA: undetectable	4p7nA-1dzbA: 20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NUM_A_Z80A201_1 (BETA-LACTOGLOBULIN)	1dzb	SCFV FRAGMENT 1F9 (Mus musculus)	5 / 8	VAL A 219 LEU A 278 ILE A 306 MET A 211 SER A 209	None	1.41A	5numA-1dzbA: undetectable	5numA-1dzbA: 17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OJ0_A_9WTA801_0 (PENICILLIN-BINDING PROTEIN 2X)	1dzb	SCFV FRAGMENT 1F9 (Mus musculus)	5 / 12	SER A 272 GLN A 290 SER A 263 GLY A 264 THR A 252	None	1.26A	5oj0A-1dzbA: undetectable	5oj0A-1dzbA: 17.19

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2KCE_B_D16B568_1","THYMIDYLATE SYNTHASE","1dzb","SCFV FRAGMENT 1F9","Mus musculus",5,"HIS A  35;ASP A 228;GLY A 292;TYR A 271;ALA A 251","None","1.23A","2kceB-1dzbA:0.0","2kceB-1dzbA:21.01"],["4E0F_A_RBFA301_2","RIBOFLAVIN SYNTHASE SUBUNIT ALPHA;RIBOFLAVIN SYNTHASE SUBUNIT ALPHA","1dzb","SCFV FRAGMENT 1F9","Mus musculus",3,"LYS A 239;THR A 284;ILE A 275","None","0.78A","4e0fB-1dzbA:1.0","4e0fB-1dzbA:23.19"],["4P7N_A_GCSA702_1","POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE N-DEACETYLASE","1dzb","SCFV FRAGMENT 1F9","Mus musculus",3,"ASP A 104;TYR A 249;TRP A  99","None","1.33A","4p7nA-1dzbA:undetectable","4p7nA-1dzbA:20.63"],["5NUM_A_Z80A201_1","BETA-LACTOGLOBULIN","1dzb","SCFV FRAGMENT 1F9","Mus musculus",5,"VAL A 219;LEU A 278;ILE A 306;MET A 211;SER A 209","None","1.41A","5numA-1dzbA:undetectable","5numA-1dzbA:17.23"],["5OJ0_A_9WTA801_0","PENICILLIN-BINDING PROTEIN 2X","1dzb","SCFV FRAGMENT 1F9","Mus musculus",5,"SER A 272;GLN A 290;SER A 263;GLY A 264;THR A 252","None","1.26A","5oj0A-1dzbA:undetectable","5oj0A-1dzbA:17.19"]]