SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dzt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_A_PAUA6001_0
(PANTOTHENATE KINASE)		 1dzt DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Salmonella
enterica) 		5 / 9 ASP A 170
LEU A 166
HIS A  63
LEU A 148
ILE A 156
 None
None
SO4  A 301 (-4.1A)
None
None
 1.49A 1sq5A-1dztA:
0.0		 1sq5A-1dztA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 1dzt DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Salmonella
enterica) 		4 / 8 SER A 140
SER A 142
SER A 143
ASN A  69
 None
 1.09A 2cmlB-1dztA:
undetectable		 2cmlB-1dztA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 1dzt DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Salmonella
enterica) 		5 / 12 ASN A  57
GLY A 121
VAL A  87
ILE A 156
ASN A 150
 None
 1.44A 3jb2A-1dztA:
0.0		 3jb2A-1dztA:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 1dzt DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Salmonella
enterica) 		4 / 8 ASP A  84
GLY A 121
TYR A 133
GLN A 111
 None
None
SO4  A 301 (-3.8A)
None
 1.03A 3s3mA-1dztA:
undetectable		 3s3mA-1dztA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1dzt DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Salmonella
enterica) 		3 / 3 LYS A  56
SER A 161
GLN A 162
 GOL  A 204 ( 4.1A)
None
None
 0.83A 3si7A-1dztA:
undetectable		 3si7A-1dztA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 1dzt DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Salmonella
enterica) 		3 / 3 PHE A 122
SER A  52
SER A  54
 None
 0.99A 3ufgB-1dztA:
0.2		 3ufgB-1dztA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1dzt DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Salmonella
enterica) 		5 / 9 ALA A 171
ALA A 168
SER A 167
ALA A 173
SER A 146
 None
None
TPE  A1000 (-3.4A)
None
None
 1.24A 4twdA-1dztA:
0.0
4twdB-1dztA:
0.1
4twdC-1dztA:
0.0
4twdD-1dztA:
0.0
4twdE-1dztA:
0.0		 4twdA-1dztA:
20.51
4twdB-1dztA:
20.51
4twdC-1dztA:
20.51
4twdD-1dztA:
20.51
4twdE-1dztA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 1dzt DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Salmonella
enterica) 		4 / 8 ILE A 147
TRP A 158
VAL A  85
ASP A  88
 None
 1.05A 5vlmF-1dztA:
undetectable		 5vlmF-1dztA:
24.53