SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1e19'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 9 GLY A 219
GLU A 225
ILE A 118
HIS A 173
GLY A 172
 None
 1.41A 1acjA-1e19A:
undetectable		 1acjA-1e19A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
 None
 0.80A 1fbyA-1e19A:
undetectable		 1fbyA-1e19A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
 None
 0.81A 1fbyB-1e19A:
undetectable		 1fbyB-1e19A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.95A 1fm6A-1e19A:
undetectable		 1fm6A-1e19A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.91A 1fm6U-1e19A:
undetectable		 1fm6U-1e19A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.93A 1fm9A-1e19A:
undetectable		 1fm9A-1e19A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		4 / 6 HIS A  51
ILE A  49
ALA A 300
VAL A  47
 None
 0.96A 1hk1A-1e19A:
0.6		 1hk1A-1e19A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 11 GLY A  54
HIS A  51
SER A  59
GLY A  11
LEU A 297
 None
None
None
ADP  A 315 (-3.5A)
None
 1.17A 1jzsA-1e19A:
1.7		 1jzsA-1e19A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.91A 1k74A-1e19A:
undetectable		 1k74A-1e19A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.90A 1xdkA-1e19A:
undetectable		 1xdkA-1e19A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.90A 1xdkE-1e19A:
undetectable		 1xdkE-1e19A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.98A 1xiuA-1e19A:
undetectable		 1xiuA-1e19A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 ILE A  37
ALA A  34
ALA A  96
VAL A   5
LEU A 234
 None
 0.93A 1xiuB-1e19A:
undetectable		 1xiuB-1e19A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.97A 1xlsA-1e19A:
undetectable		 1xlsA-1e19A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.96A 1xlsB-1e19A:
undetectable		 1xlsB-1e19A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.96A 1xlsC-1e19A:
undetectable		 1xlsC-1e19A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.96A 1xlsD-1e19A:
undetectable		 1xlsD-1e19A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 ILE A  37
ALA A  34
ASN A  12
LEU A  97
ALA A  96
 None
 0.84A 2aclG-1e19A:
undetectable		 2aclG-1e19A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 GLY A  54
LEU A 217
ASP A 216
ASP A 169
SER A 192
 None
 1.19A 2b9eA-1e19A:
4.1		 2b9eA-1e19A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		3 / 3 PRO A 132
THR A 130
PRO A 166
 None
 0.86A 2d55C-1e19A:
undetectable		 2d55C-1e19A:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 10 ILE A 188
ILE A  49
LEU A  97
ASN A  99
VAL A  30
 None
 1.26A 2nnhB-1e19A:
0.0		 2nnhB-1e19A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		4 / 8 ILE A  49
ILE A   7
ILE A  93
ALA A 295
 None
 0.70A 2nniA-1e19A:
0.0		 2nniA-1e19A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 GLY A 219
ALA A 218
ASP A 216
ASP A 214
GLY A  52
ILE A 213
 None
 1.38A 3d1xA-1e19A:
undetectable		 3d1xA-1e19A:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 ILE A 233
ASP A 214
LEU A 217
ALA A 218
ILE A 282
 None
 1.09A 3dauA-1e19A:
undetectable		 3dauA-1e19A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 ILE A  37
ALA A  34
LEU A  97
VAL A   5
LEU A 234
 None
 1.05A 3dzuA-1e19A:
undetectable		 3dzuA-1e19A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 ILE A  37
ALA A  34
ASN A  12
LEU A  97
ALA A  96
 None
 0.94A 3dzyA-1e19A:
undetectable		 3dzyA-1e19A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
 None
 0.72A 3dzyA-1e19A:
undetectable		 3dzyA-1e19A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		4 / 5 PRO A 168
VAL A 119
THR A  50
GLY A 193
 None
 1.21A 3elzB-1e19A:
0.0		 3elzB-1e19A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 8 ALA A 218
ASP A 216
ASP A 214
GLY A  52
VAL A 197
 None
 1.43A 3em6A-1e19A:
undetectable		 3em6A-1e19A:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 8 GLY A 219
ALA A 218
ASP A 216
ASP A 214
GLY A  52
 None
 1.26A 3em6A-1e19A:
undetectable		 3em6A-1e19A:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 9 GLY A 219
ALA A 218
ASP A 214
GLY A  52
THR A 115
 None
 1.02A 3gguB-1e19A:
undetectable		 3gguB-1e19A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.94A 3h0aA-1e19A:
undetectable		 3h0aA-1e19A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 ALA A 218
ASP A 214
GLY A  52
VAL A 197
ALA A 191
 None
 1.19A 3n3iA-1e19A:
undetectable		 3n3iA-1e19A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 1.00A 3oapA-1e19A:
undetectable		 3oapA-1e19A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 9 GLY A 194
ILE A 114
GLY A  90
ILE A  93
ILE A 179
 None
 0.97A 3s53A-1e19A:
undetectable		 3s53A-1e19A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 VAL A   6
ILE A 213
GLY A 193
GLY A 196
ILE A 190
 None
 0.81A 4iv0A-1e19A:
2.8		 4iv0A-1e19A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 VAL A   6
ILE A 213
GLY A 193
GLY A 196
ILE A 190
 None
 0.84A 4mwzB-1e19A:
3.0		 4mwzB-1e19A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		4 / 8 GLU A 265
VAL A 257
LEU A 260
GLY A 275
 None
 0.90A 4r3aA-1e19A:
undetectable		 4r3aA-1e19A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 7 GLU A 305
ILE A  40
ARG A   4
ILE A 230
MET A 232
 None
 1.47A 4xumA-1e19A:
0.0		 4xumA-1e19A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 11 ILE A  37
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.92A 5ji0A-1e19A:
undetectable		 5ji0A-1e19A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 GLY A 219
ALA A 218
ASP A 216
ASP A 214
GLY A  52
ILE A 213
 None
 1.37A 5kqxA-1e19A:
undetectable		 5kqxA-1e19A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		4 / 8 LEU A   9
LEU A  97
ILE A 114
THR A 112
 None
 0.90A 5ljbA-1e19A:
undetectable		 5ljbA-1e19A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.94A 5uanA-1e19A:
undetectable		 5uanA-1e19A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.91A 5z12B-1e19A:
undetectable		 5z12B-1e19A:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		6 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
VAL A   5
LEU A 234
 None
 0.99A 5z12C-1e19A:
undetectable		 5z12C-1e19A:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 12 ILE A  37
ALA A  34
LEU A  97
ALA A  96
LEU A 234
 None
 0.96A 6a5zL-1e19A:
undetectable		 6a5zL-1e19A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 1e19 CARBAMATE KINASE
(Pyrococcus
furiosus) 		5 / 7 GLY A 193
GLY A 194
GLY A  52
GLY A  11
GLY A  10
 None
None
None
ADP  A 315 (-3.5A)
ADP  A 315 (-3.6A)
 1.02A 6ag0A-1e19A:
undetectable		 6ag0A-1e19A:
14.29