SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1e1c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 6 ILE A 220
ARG A 219
TYR A 212
PHE A 556
 None
 1.38A 1e73M-1e1cA:
2.9		 1e73M-1e1cA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 7 TYR A  89
GLN A 197
SER A 239
TYR A 243
 DCA  A 801 (-4.0A)
None
DCA  A 801 ( 4.1A)
B12  A 800 ( 4.6A)
 1.32A 1eiiA-1e1cA:
0.0		 1eiiA-1e1cA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 GLU A 255
ILE A 240
TYR A 266
ILE A 200
ILE A 221
 None
 1.08A 1fklA-1e1cA:
undetectable		 1fklA-1e1cA:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 ALA A 303
ALA A 304
LEU A 260
LEU A 416
ALA A 417
 None
 0.94A 1fm9A-1e1cA:
undetectable		 1fm9A-1e1cA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 7 VAL A 684
GLY A 653
THR A 640
ILE A 682
 None
B12  A 800 ( 3.9A)
None
None
 0.82A 1gtnC-1e1cA:
undetectable
1gtnD-1e1cA:
undetectable		 1gtnC-1e1cA:
8.54
1gtnD-1e1cA:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 ALA A 303
ALA A 304
LEU A 260
LEU A 416
ALA A 417
 None
 0.93A 1k74A-1e1cA:
undetectable		 1k74A-1e1cA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 11 THR A 251
GLY A 249
GLU A 247
GLU A 255
GLU A 297
 None
None
B12  A 800 (-4.6A)
None
None
 1.40A 1odiA-1e1cA:
0.8		 1odiA-1e1cA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 ALA A 303
ALA A 304
LEU A 260
LEU A 416
ALA A 417
 None
 0.85A 1xlsA-1e1cA:
undetectable		 1xlsA-1e1cA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 ALA A 303
ALA A 304
LEU A 260
LEU A 416
ALA A 417
 None
 0.85A 1xlsB-1e1cA:
undetectable		 1xlsB-1e1cA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 ALA A 303
ALA A 304
LEU A 260
LEU A 416
ALA A 417
 None
 0.86A 1xlsC-1e1cA:
undetectable		 1xlsC-1e1cA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 ALA A 303
ALA A 304
LEU A 260
LEU A 416
ALA A 417
 None
 0.85A 1xlsD-1e1cA:
undetectable		 1xlsD-1e1cA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 ALA A 303
ALA A 304
LEU A 260
LEU A 416
ALA A 417
 None
 0.99A 2aclA-1e1cA:
undetectable
2aclE-1e1cA:
undetectable		 2aclA-1e1cA:
16.42
2aclE-1e1cA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 ALA A 303
ALA A 304
LEU A 260
LEU A 416
ALA A 417
 None
 0.98A 2aclG-1e1cA:
undetectable		 2aclG-1e1cA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 8 THR A 259
THR A 327
ASP A 199
ILE A 238
 None
 0.94A 2qbmA-1e1cA:
0.0		 2qbmA-1e1cA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 8 LEU A 390
PRO A 402
VAL A 298
GLY A 358
 None
 1.06A 2qd5B-1e1cA:
5.7		 2qd5B-1e1cA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		3 / 3 GLU A 690
GLN A 339
ARG A 471
 None
 0.90A 2w3bB-1e1cA:
undetectable		 2w3bB-1e1cA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 8 THR A 121
ILE A 174
ASP A 118
SER A 127
 None
 1.12A 2xytE-1e1cA:
0.0		 2xytE-1e1cA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 8 THR A 121
ILE A 174
ASP A 118
SER A 127
 None
 1.05A 2xytH-1e1cA:
0.0		 2xytH-1e1cA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 7 THR A 121
ILE A 174
ASP A 118
SER A 127
 None
 1.08A 2xytI-1e1cA:
0.0		 2xytI-1e1cA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 8 TYR A 243
SER A 362
GLN A 197
SER A 239
 B12  A 800 ( 4.6A)
DCA  A 801 (-3.4A)
None
DCA  A 801 ( 4.1A)
 1.00A 2xz5B-1e1cA:
0.0
2xz5E-1e1cA:
0.0		 2xz5B-1e1cA:
15.66
2xz5E-1e1cA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 8 VAL A 649
ARG A 596
SER A 717
TYR A 621
 None
None
None
B12  A 800 (-4.7A)
 1.32A 2y05A-1e1cA:
2.2
2y05B-1e1cA:
3.4		 2y05A-1e1cA:
18.36
2y05B-1e1cA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 5 LEU A 668
GLN A 643
THR A 640
THR A 683
 None
None
None
B12  A 800 ( 4.9A)
 1.30A 2zj0B-1e1cA:
4.3		 2zj0B-1e1cA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 5 LEU A 668
GLN A 643
THR A 640
THR A 683
 None
None
None
B12  A 800 ( 4.9A)
 1.32A 2zj0C-1e1cA:
2.1		 2zj0C-1e1cA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 4 LEU A 668
GLN A 643
THR A 640
THR A 683
 None
None
None
B12  A 800 ( 4.9A)
 1.31A 2zj0D-1e1cA:
4.2		 2zj0D-1e1cA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 8 PHE A 280
GLY A 270
ALA A 269
GLU A 428
 None
 0.74A 3aruA-1e1cA:
5.1		 3aruA-1e1cA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 5 LEU A 668
GLN A 643
THR A 640
THR A 683
 None
None
None
B12  A 800 ( 4.9A)
 1.28A 3ce6B-1e1cA:
4.9		 3ce6B-1e1cA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 10 ILE A 174
ILE A 196
PHE A 287
TYR A  89
ARG A 207
 None
None
DCA  A 801 ( 4.5A)
DCA  A 801 (-4.0A)
B12  A 800 (-3.9A)
 1.35A 3elzB-1e1cA:
0.0		 3elzB-1e1cA:
11.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 ALA A 303
ALA A 304
LEU A 260
LEU A 416
ALA A 417
 None
 0.97A 3fc6C-1e1cA:
undetectable		 3fc6C-1e1cA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 GLY A 194
VAL A 163
LEU A 152
VAL A 115
ILE A 143
 None
 0.95A 3frqB-1e1cA:
0.0		 3frqB-1e1cA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 11 GLY A 137
GLY A 140
ASP A 118
THR A 121
ALA A 133
 None
B12  A 800 ( 4.3A)
None
None
None
 1.00A 3g88A-1e1cA:
0.0		 3g88A-1e1cA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 11 GLY A 137
GLY A 140
ASP A 118
THR A 121
ALA A 133
 None
B12  A 800 ( 4.3A)
None
None
None
 1.00A 3g88B-1e1cA:
0.0		 3g88B-1e1cA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 6 GLY A 708
GLN A 339
ARG A 471
ILE A 457
 B12  A 800 ( 4.4A)
None
None
None
 1.14A 3kvvA-1e1cA:
undetectable		 3kvvA-1e1cA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 6 GLY A 708
GLN A 339
ARG A 471
ILE A 457
 B12  A 800 ( 4.4A)
None
None
None
 1.15A 3kvvB-1e1cA:
2.7		 3kvvB-1e1cA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 6 GLY A 708
GLN A 339
ARG A 471
ILE A 457
 B12  A 800 ( 4.4A)
None
None
None
 1.13A 3kvvC-1e1cA:
2.7		 3kvvC-1e1cA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 6 GLY A 708
GLN A 339
ARG A 471
ILE A 457
 B12  A 800 ( 4.4A)
None
None
None
 1.11A 3kvvE-1e1cA:
2.6		 3kvvE-1e1cA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 6 GLY A 708
GLN A 339
ARG A 471
ILE A 457
 B12  A 800 ( 4.4A)
None
None
None
 1.16A 3kvvF-1e1cA:
2.8		 3kvvF-1e1cA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 8 ALA A 380
ALA A 383
THR A 348
LEU A 336
 None
 1.01A 3l4dD-1e1cA:
undetectable		 3l4dD-1e1cA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 11 GLY A 700
LEU A 672
ARG A 677
LEU A 681
LEU A 668
 None
 1.32A 3ndvA-1e1cA:
0.0
3ndvB-1e1cA:
0.0		 3ndvA-1e1cA:
20.96
3ndvB-1e1cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 11 LEU A 668
GLY A 700
LEU A 672
ARG A 677
LEU A 681
 None
 1.32A 3ndvA-1e1cA:
0.0
3ndvB-1e1cA:
0.0		 3ndvA-1e1cA:
20.96
3ndvB-1e1cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 11 GLY A 700
LEU A 672
ARG A 677
LEU A 681
LEU A 668
 None
 1.32A 3ndvC-1e1cA:
0.0
3ndvD-1e1cA:
0.0		 3ndvC-1e1cA:
20.96
3ndvD-1e1cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 11 LEU A 668
GLY A 700
LEU A 672
ARG A 677
LEU A 681
 None
 1.31A 3ndvC-1e1cA:
0.0
3ndvD-1e1cA:
0.0		 3ndvC-1e1cA:
20.96
3ndvD-1e1cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_A_CP6A602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 VAL A 298
ALA A 355
PHE A 294
THR A 396
SER A 394
 None
 1.16A 3qfxA-1e1cA:
undetectable		 3qfxA-1e1cA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_B_CP6B702_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 VAL A 298
ALA A 355
PHE A 294
THR A 396
SER A 394
 None
 1.16A 3qfxB-1e1cA:
undetectable		 3qfxB-1e1cA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		3 / 3 PRO A 375
THR A 376
LEU A 368
 None
 0.80A 3ttrA-1e1cA:
1.7		 3ttrA-1e1cA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		3 / 3 LEU A 175
MET A 167
ASP A 199
 None
 0.86A 3v5wA-1e1cA:
undetectable		 3v5wA-1e1cA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 7 GLU A 447
ILE A 566
GLU A 448
VAL A 427
 None
 1.10A 4a97A-1e1cA:
0.0		 4a97A-1e1cA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 7 GLU A 447
ILE A 566
GLU A 448
VAL A 427
 None
 1.02A 4a97D-1e1cA:
undetectable		 4a97D-1e1cA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 7 GLU A 447
ILE A 566
GLU A 448
VAL A 427
 None
 1.05A 4a97H-1e1cA:
0.0		 4a97H-1e1cA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 10 ALA A  41
ILE A 446
HIS A 423
ILE A 254
ASP A 253
 None
 1.08A 4dtaA-1e1cA:
undetectable		 4dtaA-1e1cA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 7 GLY A 169
ILE A 200
GLU A 203
MET A 149
 None
 0.93A 4g0vA-1e1cA:
1.3		 4g0vA-1e1cA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 5 HIS A 650
ARG A 596
GLU A 594
LEU A 726
 None
 1.32A 4ig5B-1e1cA:
undetectable		 4ig5B-1e1cA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 8 GLY A 546
ARG A 131
PRO A 173
ILE A 211
 None
 0.97A 4j4vC-1e1cA:
0.0		 4j4vC-1e1cA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 11 THR A 683
LEU A 668
VAL A 649
ILE A 600
LEU A 718
 B12  A 800 ( 4.9A)
None
None
None
None
 1.36A 4lhmA-1e1cA:
2.7		 4lhmA-1e1cA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 LEU A 416
ASP A 253
GLU A  42
HIS A 423
GLY A 242
 None
 1.37A 4lvcB-1e1cA:
undetectable		 4lvcB-1e1cA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 5 ASP A 727
LEU A 726
ARG A 677
ARG A 596
 None
 1.40A 4p3qA-1e1cA:
undetectable		 4p3qA-1e1cA:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 7 THR A 360
GLY A 358
ALA A 355
ILE A 290
 None
 0.91A 4txnA-1e1cA:
3.3		 4txnA-1e1cA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 7 THR A 360
GLY A 358
ALA A 355
ILE A 290
 None
 0.88A 4txnB-1e1cA:
undetectable		 4txnB-1e1cA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 7 THR A 360
GLY A 358
ALA A 355
ILE A 290
 None
 0.92A 4txnC-1e1cA:
undetectable		 4txnC-1e1cA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 7 THR A 360
GLY A 358
ALA A 355
ILE A 290
 None
 0.90A 4txnD-1e1cA:
2.4		 4txnD-1e1cA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 7 THR A 706
GLY A 708
ARG A 471
ALA A 338
 None
B12  A 800 ( 4.4A)
None
None
 0.96A 4txnD-1e1cA:
2.4		 4txnD-1e1cA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		3 / 3 MET A 306
GLN A 361
TYR A  75
 None
None
DCA  A 801 (-3.9A)
 1.08A 4udcA-1e1cA:
0.0		 4udcA-1e1cA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 11 SER A 656
ALA A 373
VAL A 687
THR A 706
ILE A 704
 None
B12  A 800 (-4.5A)
B12  A 800 (-4.6A)
None
None
 1.26A 4uuuB-1e1cA:
0.0		 4uuuB-1e1cA:
11.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 ASP A 148
GLY A 539
ALA A 176
ILE A 174
ASP A 128
 None
 1.18A 4xe5A-1e1cA:
2.5		 4xe5A-1e1cA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 6 ARG A 596
ASP A 648
VAL A 628
ASP A 629
 None
 1.27A 4xqeA-1e1cA:
undetectable		 4xqeA-1e1cA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 6 ARG A 596
ASP A 648
VAL A 628
ASP A 629
 None
 1.28A 4xqeB-1e1cA:
undetectable		 4xqeB-1e1cA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 7 GLY A 422
ARG A 445
TYR A 258
ALA A 420
 None
 1.00A 5e26A-1e1cA:
2.8
5e26B-1e1cA:
2.6		 5e26A-1e1cA:
18.50
5e26B-1e1cA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 5 HIS A 650
ARG A 596
GLU A 594
LEU A 726
 None
 1.32A 5ff1A-1e1cA:
0.0		 5ff1A-1e1cA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 5 HIS A 650
ARG A 596
GLU A 594
LEU A 726
 None
 1.32A 5ff1A-1e1cA:
0.0		 5ff1A-1e1cA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 5 HIS A 650
ARG A 596
GLU A 594
LEU A 726
 None
 1.33A 5ff1B-1e1cA:
0.0		 5ff1B-1e1cA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 5 HIS A 650
ARG A 596
GLU A 594
LEU A 726
 None
 1.33A 5ff1B-1e1cA:
0.0		 5ff1B-1e1cA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		3 / 3 PRO A 120
ILE A 688
SER A 127
 None
 0.61A 5fsaA-1e1cA:
0.0		 5fsaA-1e1cA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 ALA A 715
ASP A 627
PRO A 598
PHE A 626
GLU A 588
 None
 1.26A 5hfjA-1e1cA:
undetectable		 5hfjA-1e1cA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 ALA A 715
ASP A 627
PRO A 598
PHE A 626
GLU A 588
 None
 1.23A 5hfjG-1e1cA:
undetectable		 5hfjG-1e1cA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 8 PHE A 117
ILE A 174
LEU A 158
LEU A 192
 None
 0.76A 5hs1A-1e1cA:
undetectable		 5hs1A-1e1cA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 5 VAL A  46
THR A  40
ASN A 293
LEU A 412
 None
 1.11A 5m0iB-1e1cA:
0.0		 5m0iB-1e1cA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		3 / 3 ARG A 305
PHE A 287
LEU A 301
 None
DCA  A 801 ( 4.5A)
None
 0.83A 5x1bC-1e1cA:
undetectable		 5x1bC-1e1cA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 12 LEU A 489
ASP A 128
PRO A 637
GLY A 606
LEU A 664
 None
 1.17A 6b0lB-1e1cA:
0.0		 6b0lB-1e1cA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		5 / 10 LEU A 301
LEU A 416
ASP A 253
ILE A 290
GLY A 291
 None
 1.27A 6dm0B-1e1cA:
3.1
6dm0C-1e1cA:
4.0		 6dm0B-1e1cA:
7.10
6dm0C-1e1cA:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		3 / 3 GLN A 110
TYR A 102
ASN A 105
 None
 0.91A 6dwdC-1e1cA:
0.0		 6dwdC-1e1cA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 5 ARG A 123
ARG A 207
GLY A 169
ASN A 168
 None
B12  A 800 (-3.9A)
None
None
 1.19A 6dwjB-1e1cA:
0.0
6dwjD-1e1cA:
0.0		 6dwjB-1e1cA:
23.78
6dwjD-1e1cA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN
(Propionibacteriu
m
freudenreichii) 		4 / 4 ASP A 148
ILE A 174
PRO A 173
LEU A 177
 None
 1.05A 6mkeA-1e1cA:
0.0		 6mkeA-1e1cA:
8.03