SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1e29'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 1e29 CYTOCHROME C549
(Synechocystis
sp.) 		5 / 12 ALA A  62
LEU A  59
LEU A  72
PHE A  75
THR A  46
 HEC  A 201 (-3.6A)
HEC  A 201 (-4.5A)
HEC  A 201 (-4.9A)
HEC  A 201 (-4.1A)
HEC  A 201 ( 4.4A)
 1.16A 2oipD-1e29A:
undetectable		 2oipD-1e29A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_D_MTXD615_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 1e29 CYTOCHROME C549
(Synechocystis
sp.) 		5 / 12 ALA A  62
LEU A  59
LEU A  72
PHE A  75
THR A  46
 HEC  A 201 (-3.6A)
HEC  A 201 (-4.5A)
HEC  A 201 (-4.9A)
HEC  A 201 (-4.1A)
HEC  A 201 ( 4.4A)
 1.09A 3hj3D-1e29A:
undetectable		 3hj3D-1e29A:
13.93