SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1e32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1e32 P97
(Mus
musculus) 		5 / 12 LEU A 411
LEU A 414
CYH A 415
ALA A 418
MET A 449
 None
 0.70A 1s9pC-1e32A:
undetectable		 1s9pC-1e32A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 1e32 P97
(Mus
musculus) 		4 / 7 ASP A 120
VAL A 123
GLY A 186
THR A 127
 None
 0.68A 1t7iB-1e32A:
2.7		 1t7iB-1e32A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 1e32 P97
(Mus
musculus) 		4 / 7 ASP A 120
VAL A 123
GLY A 186
THR A 127
 None
 0.69A 1t7jB-1e32A:
2.9		 1t7jB-1e32A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1e32 P97
(Mus
musculus) 		3 / 3 GLU A 195
GLU A 200
LEU A 153
 None
 0.73A 1v8bA-1e32A:
undetectable		 1v8bA-1e32A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1e32 P97
(Mus
musculus) 		3 / 3 GLU A 195
GLU A 200
LEU A 153
 None
 0.75A 1v8bB-1e32A:
undetectable		 1v8bB-1e32A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1e32 P97
(Mus
musculus) 		3 / 3 ASP A  98
ARG A  89
ARG A  95
 None
 0.90A 2j9dA-1e32A:
0.0
2j9dC-1e32A:
0.0		 2j9dA-1e32A:
17.08
2j9dC-1e32A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1e32 P97
(Mus
musculus) 		5 / 12 ILE A 303
PHE A 290
ALA A 339
LEU A 224
ILE A 301
 None
 1.28A 2xkwB-1e32A:
undetectable		 2xkwB-1e32A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 1e32 P97
(Mus
musculus) 		3 / 3 ARG A  95
ASP A 204
ASN A  90
 None
 0.79A 2zzmA-1e32A:
undetectable		 2zzmA-1e32A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1e32 P97
(Mus
musculus) 		5 / 12 ALA A 259
ALA A 257
VAL A 367
ILE A 369
LEU A 213
 None
 0.99A 3h0aA-1e32A:
undetectable		 3h0aA-1e32A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1e32 P97
(Mus
musculus) 		5 / 11 SER A  40
LEU A  41
ILE A  70
VAL A  57
VAL A  88
 None
 1.15A 3w67A-1e32A:
2.4		 3w67A-1e32A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 1e32 P97
(Mus
musculus) 		5 / 11 ILE A 216
ILE A 254
ALA A 346
ALA A 345
VAL A 258
 None
 1.17A 4h1nA-1e32A:
0.0		 4h1nA-1e32A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e32 P97
(Mus
musculus) 		4 / 8 THR A 249
GLY A 208
GLY A 207
VAL A 206
 ADP  A 800 (-4.5A)
None
ADP  A 800 (-4.0A)
ADP  A 800 (-4.0A)
 0.80A 4qvvK-1e32A:
undetectable
4qvvL-1e32A:
undetectable		 4qvvK-1e32A:
16.38
4qvvL-1e32A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e32 P97
(Mus
musculus) 		4 / 8 THR A 249
GLY A 208
GLY A 207
VAL A 206
 ADP  A 800 (-4.5A)
None
ADP  A 800 (-4.0A)
ADP  A 800 (-4.0A)
 0.80A 4qvvY-1e32A:
undetectable
4qvvZ-1e32A:
undetectable		 4qvvY-1e32A:
16.38
4qvvZ-1e32A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1e32 P97
(Mus
musculus) 		5 / 12 LEU A 357
THR A 347
ALA A 345
VAL A 343
ILE A 303
 None
 0.96A 4x1yB-1e32A:
undetectable		 4x1yB-1e32A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 1e32 P97
(Mus
musculus) 		3 / 3 LEU A  41
ASP A  47
ILE A  70
 None
 0.52A 4xi3D-1e32A:
0.0		 4xi3D-1e32A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSH_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1e32 P97
(Mus
musculus) 		4 / 5 ARG A 155
LEU A 198
ASN A  85
VAL A  87
 None
 1.31A 5cshB-1e32A:
undetectable		 5cshB-1e32A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1e32 P97
(Mus
musculus) 		4 / 5 ARG A 155
LEU A 198
ASN A  85
VAL A  87
 None
 1.34A 5os7B-1e32A:
undetectable		 5os7B-1e32A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1e32 P97
(Mus
musculus) 		6 / 12 MET A 388
ALA A 422
PHE A 452
GLN A 382
LEU A 396
VAL A 399
 None
 1.46A 5tudD-1e32A:
undetectable		 5tudD-1e32A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1e32 P97
(Mus
musculus) 		4 / 5 ARG A 155
LEU A 198
ASN A  85
VAL A  87
 None
 1.34A 6gmdA-1e32A:
undetectable		 6gmdA-1e32A:
21.69