SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1e33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 ALA P 464
LEU P 462
LEU P 441
LEU P 428
 None
 0.97A 1dvtA-1e33P:
0.0
1dvtB-1e33P:
undetectable		 1dvtA-1e33P:
13.82
1dvtB-1e33P:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 7 GLN P 476
SER P 475
TRP P 124
GLN P 139
 None
 1.33A 1eiiA-1e33P:
0.0		 1eiiA-1e33P:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 6 LEU P 268
THR P 260
ALA P 264
LEU P 270
 None
 1.27A 1etb2-1e33P:
undetectable		 1etb2-1e33P:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_C_T44C601_1
(TRANSTHYRETIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 9 LEU P 428
LEU P 441
LYS P 457
LEU P 453
ALA P 455
 None
 1.36A 1sn0A-1e33P:
0.0
1sn0C-1e33P:
0.0		 1sn0A-1e33P:
14.11
1sn0C-1e33P:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 6 PHE P 141
THR P 106
VAL P 107
LEU P 111
 None
 1.05A 2e1qC-1e33P:
undetectable		 2e1qC-1e33P:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 SER P 225
TYR P 201
HIS P 151
HIS P 226
 None
 1.03A 2v0gA-1e33P:
undetectable		 2v0gA-1e33P:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 ALA P 314
ALA P 316
GLY P 325
ALA P  53
 None
 0.83A 2vh3B-1e33P:
undetectable		 2vh3B-1e33P:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 7 PRO P 284
GLY P 283
LEU P 251
PHE P 247
 None
 0.95A 2vl2B-1e33P:
undetectable		 2vl2B-1e33P:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 TYR P 429
ARG P 299
ARG P 390
ARG P 311
 None
 1.49A 2vxaA-1e33P:
0.0
2vxaC-1e33P:
undetectable
2vxaE-1e33P:
0.0		 2vxaA-1e33P:
9.05
2vxaC-1e33P:
9.05
2vxaE-1e33P:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 ARG P 390
TYR P 429
ARG P 299
ARG P 311
 None
 1.44A 2vxaA-1e33P:
0.0
2vxaB-1e33P:
0.0
2vxaK-1e33P:
undetectable		 2vxaA-1e33P:
9.05
2vxaB-1e33P:
9.05
2vxaK-1e33P:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 ARG P 390
TYR P 429
ARG P 299
ARG P 311
 None
 1.47A 2vxaB-1e33P:
0.0
2vxaC-1e33P:
undetectable
2vxaG-1e33P:
undetectable		 2vxaB-1e33P:
9.05
2vxaC-1e33P:
9.05
2vxaG-1e33P:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 TYR P 429
ARG P 299
ARG P 390
ARG P 311
 None
 1.46A 2vxaD-1e33P:
0.0
2vxaF-1e33P:
0.0
2vxaI-1e33P:
0.0		 2vxaD-1e33P:
9.05
2vxaF-1e33P:
9.05
2vxaI-1e33P:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 ARG P 390
TYR P 429
ARG P 299
ARG P 311
 None
 1.46A 2vxaD-1e33P:
0.0
2vxaE-1e33P:
0.0
2vxaL-1e33P:
0.0		 2vxaD-1e33P:
9.05
2vxaE-1e33P:
9.05
2vxaL-1e33P:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 ARG P 311
ARG P 390
TYR P 429
ARG P 299
 None
 1.46A 2vxaB-1e33P:
0.0
2vxaG-1e33P:
0.0
2vxaH-1e33P:
0.0		 2vxaB-1e33P:
9.05
2vxaG-1e33P:
9.05
2vxaH-1e33P:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 ARG P 390
TYR P 429
ARG P 299
ARG P 311
 None
 1.47A 2vxaH-1e33P:
0.0
2vxaI-1e33P:
0.0
2vxaJ-1e33P:
0.0		 2vxaH-1e33P:
9.05
2vxaI-1e33P:
9.05
2vxaJ-1e33P:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 ARG P 311
TYR P 429
ARG P 299
ARG P 390
 None
 1.46A 2vxaD-1e33P:
0.0
2vxaJ-1e33P:
0.0
2vxaL-1e33P:
0.0		 2vxaD-1e33P:
9.05
2vxaJ-1e33P:
9.05
2vxaL-1e33P:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_K_RBFK200_1
(DODECIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 ARG P 311
ARG P 390
TYR P 429
ARG P 299
 None
 1.48A 2vxaH-1e33P:
0.0
2vxaJ-1e33P:
0.0
2vxaK-1e33P:
undetectable		 2vxaH-1e33P:
9.05
2vxaJ-1e33P:
9.05
2vxaK-1e33P:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 ARG P 311
ARG P 390
TYR P 429
ARG P 299
 None
 1.49A 2vxaA-1e33P:
0.0
2vxaK-1e33P:
undetectable
2vxaL-1e33P:
0.0		 2vxaA-1e33P:
9.05
2vxaK-1e33P:
9.05
2vxaL-1e33P:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1470_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 5 ARG P 217
ALA P 212
ASP P 211
GLU P 215
 None
None
NDG  P 602 (-3.9A)
None
 0.89A 2xrzA-1e33P:
0.8		 2xrzA-1e33P:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 12 GLY P  79
ASP P 335
ALA P 341
VAL P 351
LEU P 348
 None
 1.00A 2yqzA-1e33P:
undetectable		 2yqzA-1e33P:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		3 / 3 SER P 406
GLY P 303
GLY P 309
 None
 0.53A 3bogA-1e33P:
0.0
3bogC-1e33P:
0.0		 3bogA-1e33P:
undetectable
3bogC-1e33P:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 6 ASP P 173
HIS P 151
ASP P  29
HIS P 229
 None
None
MG  P 603 (-3.1A)
None
 1.15A 3c0zC-1e33P:
2.4		 3c0zC-1e33P:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 12 HIS P 405
GLY P  32
GLU P 312
GLY P 283
HIS P 229
 None
 1.38A 3f8wB-1e33P:
undetectable		 3f8wB-1e33P:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		3 / 3 SER P 150
ASP P  29
ASN P 282
 DDZ  P  69 ( 4.9A)
MG  P 603 (-3.1A)
MG  P 603 (-2.9A)
 0.97A 3lsfB-1e33P:
0.0
3lsfE-1e33P:
0.2		 3lsfB-1e33P:
18.93
3lsfE-1e33P:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 12 GLY P 119
VAL P 107
LEU P 340
THR P 274
PHE P 219
 None
 1.28A 3mnoA-1e33P:
undetectable		 3mnoA-1e33P:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 12 GLY P 119
VAL P 107
LEU P 340
THR P 274
PHE P 219
 None
 1.28A 3mnpA-1e33P:
undetectable		 3mnpA-1e33P:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 12 LEU P  49
CYH P  38
HIS P  41
LEU P  31
GLY P  32
 None
 1.29A 3okxA-1e33P:
0.0		 3okxA-1e33P:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 12 LEU P  49
CYH P  38
HIS P  41
LEU P  31
GLY P  32
 None
 1.24A 3okxB-1e33P:
0.0		 3okxB-1e33P:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 12 LEU P 271
ALA P 264
GLY P 266
LEU P 268
ALA P 205
 None
 1.31A 3ou7C-1e33P:
undetectable		 3ou7C-1e33P:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 ASP P 152
SER P 150
HIS P 229
GLU P 481
 None
DDZ  P  69 ( 4.9A)
None
None
 0.90A 3sg9B-1e33P:
undetectable		 3sg9B-1e33P:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		3 / 3 ASP P 207
LEU P 117
VAL P  24
 None
NDG  P 602 (-4.9A)
None
 0.64A 4jecB-1e33P:
0.0		 4jecB-1e33P:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 5 HIS P 226
PHE P 144
LEU P 197
PRO P 192
 None
 1.36A 4o8zA-1e33P:
undetectable		 4o8zA-1e33P:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		3 / 3 SER P 418
ASP P  30
ASP P 407
 None
MG  P 603 (-3.2A)
None
 0.81A 4uckA-1e33P:
undetectable		 4uckA-1e33P:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		3 / 3 LYS P 463
ARG P  84
VAL P  83
 None
 0.97A 4x3uA-1e33P:
1.6
4x3uB-1e33P:
1.2		 4x3uA-1e33P:
7.98
4x3uB-1e33P:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		3 / 3 VAL P 326
THR P  60
ARG P  58
 None
 0.75A 5b2sB-1e33P:
0.0		 5b2sB-1e33P:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		3 / 3 VAL P 326
THR P  60
ARG P  58
 None
 0.78A 5b2tB-1e33P:
undetectable		 5b2tB-1e33P:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_B_1FLB1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 9 LEU P 197
LEU P 145
PRO P 192
PRO P 136
MET P 120
 None
NDG  P 601 ( 4.9A)
None
None
None
 1.39A 5g48B-1e33P:
0.0		 5g48B-1e33P:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 12 LEU P 336
GLY P  79
TYR P 222
PHE P 141
MET P 120
 None
 1.49A 5kklB-1e33P:
undetectable		 5kklB-1e33P:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 10 LEU P 182
GLY P 129
GLY P 132
GLN P 190
LEU P 485
 None
 0.99A 5l0zB-1e33P:
undetectable		 5l0zB-1e33P:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 9 ILE P  26
GLY P 259
ASN P  48
MET P 202
ALA P 199
 None
 1.39A 5x66C-1e33P:
0.0		 5x66C-1e33P:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 12 HIS P 229
GLY P 303
ALA P 404
LEU P  68
PRO P  89
 None
None
None
DDZ  P  69 ( 3.7A)
None
 1.11A 6b3aA-1e33P:
undetectable		 6b3aA-1e33P:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 12 HIS P 229
GLY P 303
ALA P 404
LEU P  68
PRO P  89
 None
None
None
DDZ  P  69 ( 3.7A)
None
 1.15A 6b3bA-1e33P:
2.1		 6b3bA-1e33P:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		5 / 12 GLY P  98
TYR P 149
PRO P 192
GLU P 481
GLY P 480
 None
 1.35A 6gngA-1e33P:
undetectable		 6gngA-1e33P:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 8 HIS P 125
HIS P 227
ASP P 281
GLU P 312
 DDZ  P  69 ( 3.9A)
None
MG  P 603 (-2.2A)
None
 1.18A 6mn4C-1e33P:
0.0		 6mn4C-1e33P:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1e33 ARYLSULFATASE A
(Homo
sapiens) 		4 / 7 THR P 408
ARG P 299
HIS P 397
ASP P 411
 None
 1.32A 6mn4E-1e33P:
0.0		 6mn4E-1e33P:
21.14