SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1e4w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 1e4w TAB2
(Mus
musculus) 		3 / 3 GLY H  42
PRO H  41
ALA H  88
 None
 0.56A 4qn9B-1e4wH:
undetectable		 4qn9B-1e4wH:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 1e4w TAB2
(Mus
musculus) 		4 / 6 MET H  80
ASN H  76
VAL H  71
LEU H  69
 None
 1.29A 5xdhA-1e4wH:
undetectable
5xdhC-1e4wH:
undetectable		 5xdhA-1e4wH:
16.58
5xdhC-1e4wH:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 1e4w TAB2
(Mus
musculus) 		4 / 5 MET H  80
ASN H  76
VAL H  71
LEU H  69
 None
 1.17A 5xdhB-1e4wH:
undetectable		 5xdhB-1e4wH:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 1e4w TAB2
(Mus
musculus) 		4 / 6 MET H  80
ASN H  76
VAL H  71
LEU H  69
 None
 1.18A 5xdhA-1e4wH:
undetectable
5xdhC-1e4wH:
undetectable		 5xdhA-1e4wH:
16.58
5xdhC-1e4wH:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 1e4w TAB2
(Mus
musculus) 		4 / 5 MET H  80
ASN H  76
VAL H  71
LEU H  69
 None
 1.19A 5xdhD-1e4wH:
undetectable		 5xdhD-1e4wH:
16.58