SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1e5d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		4 / 5 HIS A 226
LEU A  12
LEU A  91
GLY A  14
 FEO  A 404 ( 3.2A)
None
None
None
 1.15A 1a4lB-1e5dA:
undetectable		 1a4lB-1e5dA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 9 GLY A 227
ALA A 173
THR A  34
ILE A 171
GLY A  14
 None
 1.16A 1c9sQ-1e5dA:
undetectable
1c9sR-1e5dA:
0.0		 1c9sQ-1e5dA:
16.21
1c9sR-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 10 GLY A  14
GLY A 227
ALA A 173
THR A  34
ILE A 171
 None
 1.14A 1gtfJ-1e5dA:
0.0
1gtfK-1e5dA:
0.0		 1gtfJ-1e5dA:
16.21
1gtfK-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 11 GLY A 227
ALA A 173
THR A  34
ILE A 171
GLY A  14
 None
 1.15A 1gtfQ-1e5dA:
undetectable
1gtfR-1e5dA:
undetectable		 1gtfQ-1e5dA:
16.21
1gtfR-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 9 GLY A 227
ALA A 173
THR A  34
ILE A 171
GLY A  14
 None
 1.17A 1gtfR-1e5dA:
0.0
1gtfS-1e5dA:
0.0		 1gtfR-1e5dA:
16.21
1gtfS-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 11 GLY A 227
ALA A 173
THR A  34
ILE A 171
GLY A  14
 None
 1.16A 1gtnT-1e5dA:
undetectable
1gtnU-1e5dA:
undetectable		 1gtnT-1e5dA:
16.21
1gtnU-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 12 GLU A  81
HIS A  24
HIS A 146
ASP A 165
PRO A 224
 FEO  A 404 (-2.6A)
OXY  A 405 ( 4.8A)
FEO  A 404 (-3.3A)
FEO  A 404 ( 2.3A)
None
 1.35A 1ituA-1e5dA:
undetectable		 1ituA-1e5dA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_B_CILB452_1
(RENAL DIPEPTIDASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 12 GLU A  81
HIS A  24
HIS A 146
ASP A 165
PRO A 224
 FEO  A 404 (-2.6A)
OXY  A 405 ( 4.8A)
FEO  A 404 (-3.3A)
FEO  A 404 ( 2.3A)
None
 1.37A 1ituB-1e5dA:
undetectable		 1ituB-1e5dA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 11 ILE A 171
ASP A  17
GLY A  32
TYR A  55
ALA A  15
 None
 1.36A 1ju6A-1e5dA:
0.0		 1ju6A-1e5dA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 10 ILE A 171
ASP A  17
GLY A  32
TYR A  55
ALA A  15
 None
 1.36A 1ju6C-1e5dA:
0.0		 1ju6C-1e5dA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 11 ILE A 171
ASP A  17
GLY A  32
TYR A  55
ALA A  15
 None
 1.37A 1ju6D-1e5dA:
0.0		 1ju6D-1e5dA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 10 GLY A 227
ALA A 173
THR A  34
ILE A 171
GLY A  14
 None
 1.14A 1utdE-1e5dA:
0.0
1utdF-1e5dA:
0.0		 1utdE-1e5dA:
16.21
1utdF-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 10 GLY A 227
ALA A 173
THR A  34
ILE A 171
GLY A  14
 None
 1.15A 1utdU-1e5dA:
undetectable
1utdV-1e5dA:
undetectable		 1utdU-1e5dA:
16.21
1utdV-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		4 / 8 TYR A  35
ASP A  17
SER A  20
HIS A  24
 None
None
None
OXY  A 405 ( 4.8A)
 1.10A 2bteA-1e5dA:
2.5		 2bteA-1e5dA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		4 / 8 TYR A  35
ASP A  17
SER A  20
HIS A  24
 None
None
None
OXY  A 405 ( 4.8A)
 1.18A 2bteD-1e5dA:
2.4		 2bteD-1e5dA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		3 / 3 SER A 131
ASP A  73
ASP A  42
 None
 0.78A 2plwA-1e5dA:
2.0		 2plwA-1e5dA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		4 / 8 TYR A  35
ASP A  17
SER A  20
HIS A  24
 None
None
None
OXY  A 405 ( 4.8A)
 1.23A 2v0gA-1e5dA:
undetectable		 2v0gA-1e5dA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7P_C_SPMC503_1
(SPERMIDINE SYNTHASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 12 TYR A 193
HIS A 226
ASP A  83
ASP A 165
SER A 299
 None
FEO  A 404 ( 3.2A)
FEO  A 404 (-2.2A)
FEO  A 404 ( 2.3A)
None
 1.37A 3b7pC-1e5dA:
undetectable		 3b7pC-1e5dA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ASP A  83
LEU A  80
ASP A  49
LEU A  47
 FEO  A 404 (-2.2A)
None
None
None
 1.23A 3bj8C-1e5dA:
0.1
3bj8D-1e5dA:
0.0		 3bj8C-1e5dA:
18.09
3bj8D-1e5dA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 12 THR A 142
VAL A  76
VAL A  40
ILE A 162
THR A  46
 None
 1.09A 3czhA-1e5dA:
0.0		 3czhA-1e5dA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 12 THR A 142
VAL A  76
VAL A  40
ILE A 162
THR A  46
 None
 1.10A 3dl9A-1e5dA:
0.0		 3dl9A-1e5dA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		3 / 3 GLN A 204
THR A 205
LEU A 332
 None
 0.58A 3ondA-1e5dA:
5.4		 3ondA-1e5dA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		3 / 3 GLN A 204
THR A 205
LEU A 332
 None
 0.58A 3ondB-1e5dA:
undetectable		 3ondB-1e5dA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RLB_B_VIBB187_1
(THIT)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 12 ILE A 197
TYR A 243
GLY A 227
TYR A  35
ASN A 170
 OXY  A 405 ( 4.7A)
None
None
None
None
 1.45A 3rlbB-1e5dA:
0.0		 3rlbB-1e5dA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		4 / 7 LEU A  39
GLU A  41
LEU A  47
ILE A  72
 None
 0.88A 3s56B-1e5dA:
0.0		 3s56B-1e5dA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		3 / 3 SER A  29
ASP A  83
ASP A  49
 None
FEO  A 404 (-2.2A)
None
 0.79A 3uj7A-1e5dA:
undetectable		 3uj7A-1e5dA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		3 / 3 SER A  29
ASP A  83
ASP A  49
 None
FEO  A 404 (-2.2A)
None
 0.77A 4mwzA-1e5dA:
undetectable		 4mwzA-1e5dA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		4 / 5 TYR A  26
SER A  20
ASP A  83
ASP A  49
 None
None
FEO  A 404 (-2.2A)
None
 1.24A 4qtuB-1e5dA:
2.2		 4qtuB-1e5dA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		4 / 8 ILE A 166
LEU A  12
VAL A 160
PHE A 167
 None
 0.97A 4r38B-1e5dA:
0.0		 4r38B-1e5dA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		4 / 5 ALA A  15
TYR A  35
HIS A 293
PHE A  23
 None
 1.37A 4ze2A-1e5dA:
0.2		 4ze2A-1e5dA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 10 GLY A  14
GLY A 227
ALA A 173
THR A  34
ILE A 171
 None
 1.12A 5eevA-1e5dA:
0.0
5eevB-1e5dA:
0.0		 5eevA-1e5dA:
16.21
5eevB-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 10 GLY A  14
GLY A 227
ALA A 173
THR A  34
ILE A 171
 None
 1.12A 5eewA-1e5dA:
0.0
5eewB-1e5dA:
0.0		 5eewA-1e5dA:
16.21
5eewB-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 10 GLY A  14
GLY A 227
ALA A 173
THR A  34
ILE A 171
 None
 1.13A 5eexA-1e5dA:
0.0
5eexB-1e5dA:
0.0		 5eexA-1e5dA:
16.21
5eexB-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 10 GLY A  14
GLY A 227
ALA A 173
THR A  34
ILE A 171
 None
 1.13A 5eeyA-1e5dA:
0.0
5eeyB-1e5dA:
0.0		 5eeyA-1e5dA:
16.21
5eeyB-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 10 GLY A  14
GLY A 227
ALA A 173
THR A  34
ILE A 171
 None
 1.13A 5eezA-1e5dA:
0.0
5eezB-1e5dA:
0.0		 5eezA-1e5dA:
16.21
5eezB-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 10 GLY A  14
GLY A 227
ALA A 173
THR A  34
ILE A 171
 None
 1.13A 5ef0A-1e5dA:
0.0
5ef0B-1e5dA:
0.0		 5ef0A-1e5dA:
16.21
5ef0B-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 10 GLY A  14
GLY A 227
ALA A 173
THR A  34
ILE A 171
 None
 1.13A 5ef1A-1e5dA:
0.0
5ef1B-1e5dA:
0.0		 5ef1A-1e5dA:
16.21
5ef1B-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 10 GLY A  14
GLY A 227
ALA A 173
THR A  34
ILE A 171
 None
 1.13A 5ef2A-1e5dA:
0.0
5ef2B-1e5dA:
0.0		 5ef2A-1e5dA:
16.21
5ef2B-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 10 GLY A  14
GLY A 227
ALA A 173
THR A  34
ILE A 171
 None
 1.13A 5ef3A-1e5dA:
0.0
5ef3B-1e5dA:
0.0		 5ef3A-1e5dA:
16.21
5ef3B-1e5dA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		5 / 12 ILE A 392
ALA A 368
PHE A 277
GLY A 305
VAL A 255
 None
 0.93A 5i73A-1e5dA:
undetectable		 5i73A-1e5dA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		4 / 5 GLY A 361
THR A 360
GLY A  25
LEU A 332
 None
 0.67A 5jlcA-1e5dA:
0.4		 5jlcA-1e5dA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		4 / 5 ARG A  21
THR A  33
ALA A 172
ASP A  17
 None
 1.34A 5mfxA-1e5dA:
2.4		 5mfxA-1e5dA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		4 / 8 ASP A 165
HIS A 146
HIS A  79
HIS A 226
 FEO  A 404 ( 2.3A)
FEO  A 404 (-3.3A)
FEO  A 404 (-3.3A)
FEO  A 404 ( 3.2A)
 0.97A 5nekB-1e5dA:
undetectable		 5nekB-1e5dA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		4 / 8 ASP A 165
HIS A 146
HIS A  79
HIS A 226
 FEO  A 404 ( 2.3A)
FEO  A 404 (-3.3A)
FEO  A 404 (-3.3A)
FEO  A 404 ( 3.2A)
 0.93A 5nekD-1e5dA:
undetectable		 5nekD-1e5dA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE
(Desulfovibrio
gigas) 		3 / 3 GLY A 281
THR A 283
ASN A 253
 None
 0.53A 5odiG-1e5dA:
6.6		 5odiG-1e5dA:
20.91