SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1e5p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 1e5p APHRODISIN
(Mesocricetus
auratus) 		4 / 8 ILE A  15
ASN A  80
ASN A  96
MET A 108
 None
 0.25A 1dzmA-1e5pA:
24.9		 1dzmA-1e5pA:
33.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 1e5p APHRODISIN
(Mesocricetus
auratus) 		4 / 8 ILE A 125
LEU A 126
LEU A 118
VAL A 111
 None
 0.86A 3dcjB-1e5pA:
undetectable		 3dcjB-1e5pA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1e5p APHRODISIN
(Mesocricetus
auratus) 		4 / 5 PHE A  33
ILE A  47
PHE A  49
PHE A  31
 None
 1.05A 3owxB-1e5pA:
undetectable		 3owxB-1e5pA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1e5p APHRODISIN
(Mesocricetus
auratus) 		4 / 6 PHE A  93
ILE A  87
PRO A  84
PHE A 129
 None
 1.24A 4fgkA-1e5pA:
undetectable		 4fgkA-1e5pA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 1e5p APHRODISIN
(Mesocricetus
auratus) 		4 / 7 PHE A  33
ILE A  47
PHE A  82
ASN A  96
 None
 1.27A 4o7gA-1e5pA:
undetectable
4o7gB-1e5pA:
undetectable		 4o7gA-1e5pA:
20.72
4o7gB-1e5pA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1e5p APHRODISIN
(Mesocricetus
auratus) 		3 / 3 ARG A  34
ILE A  47
PHE A  33
 None
 0.71A 5kirA-1e5pA:
undetectable		 5kirA-1e5pA:
14.10