SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1e6z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 1e6z CHITINASE B
(Serratia
marcescens) 		6 / 9 TYR A  10
PHE A  51
GLY A  96
ASP A 142
ASP A 215
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-3.5A)
 1.01A 1e9lA-1e6zA:
42.3		 1e9lA-1e6zA:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 9 TYR A  10
PHE A  51
GLY A  96
ASP A 142
MET A 212
TYR A 214
ASP A 215
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
 0.67A 1e9lA-1e6zA:
42.3		 1e9lA-1e6zA:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 4 LEU A 432
GLY A 435
ASP A 361
TYR A 387
 None
 1.39A 1oxrA-1e6zA:
0.0		 1oxrA-1e6zA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		8 / 11 TYR A  10
PHE A  51
GLY A  96
ASP A 142
MET A 212
TYR A 214
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.72A 2a3aA-1e6zA:
12.3		 2a3aA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		10 / 11 TYR A  10
PHE A  51
GLY A  96
TRP A  97
GLU A 144
MET A 212
TYR A 214
ASP A 215
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NAG  A 503 ( 3.7A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.58A 2a3aA-1e6zA:
12.3		 2a3aA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		3 / 3 TRP A  97
GLU A 144
TYR A 145
 NAG  A 503 ( 3.7A)
NGO  A 502 (-3.4A)
None
 0.36A 2a3aA-1e6zA:
12.3		 2a3aA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		8 / 9 PHE A  51
GLY A  96
GLU A 144
MET A 212
TYR A 214
ASP A 215
TYR A 292
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.46A 2a3aB-1e6zA:
9.7		 2a3aB-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 11 TYR A  10
PHE A  51
GLY A  96
ASP A 142
TYR A 214
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-4.5A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.81A 2a3bA-1e6zA:
39.4		 2a3bA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 11 TYR A  10
PHE A  51
GLY A  96
GLU A 144
MET A 212
TYR A 214
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-3.5A)
 0.71A 2a3bA-1e6zA:
39.4		 2a3bA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		8 / 11 TYR A  10
PHE A  51
GLY A  96
MET A 212
TYR A 214
ASP A 215
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.44A 2a3bA-1e6zA:
39.4		 2a3bA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		8 / 10 PHE A  51
GLY A  96
ASP A 142
GLU A 144
MET A 212
TYR A 214
TYR A 292
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.90A 2a3bB-1e6zA:
12.7		 2a3bB-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 10 PHE A  51
GLY A  96
MET A 212
TYR A 214
ASP A 215
TYR A 292
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.44A 2a3bB-1e6zA:
12.7		 2a3bB-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 12 TYR A  10
PHE A  51
GLY A  96
ASP A 142
GLU A 144
TYR A 214
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-3.5A)
 0.96A 2a3cA-1e6zA:
12.6		 2a3cA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 12 TYR A  10
PHE A  51
GLY A  96
ASP A 142
TYR A 214
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-4.5A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.81A 2a3cA-1e6zA:
12.6		 2a3cA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 12 TYR A  10
PHE A  51
GLY A  96
GLU A 144
MET A 212
TYR A 214
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-3.5A)
 0.71A 2a3cA-1e6zA:
12.6		 2a3cA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		8 / 12 TYR A  10
PHE A  51
GLY A  96
MET A 212
TYR A 214
ASP A 215
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.44A 2a3cA-1e6zA:
12.6		 2a3cA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		8 / 12 PHE A  51
GLY A  96
ASP A 142
GLU A 144
MET A 212
TYR A 214
TYR A 292
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.89A 2a3cB-1e6zA:
12.5		 2a3cB-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 12 PHE A  51
GLY A  96
MET A 212
TYR A 214
ASP A 215
TYR A 292
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.42A 2a3cB-1e6zA:
12.5		 2a3cB-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 12 PHE A 154
ASN A 166
ILE A 141
ILE A 183
LEU A 165
 None
 1.21A 2bjfA-1e6zA:
0.0		 2bjfA-1e6zA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 12 LEU A  44
ILE A  47
PHE A  31
VAL A  33
LEU A  81
 None
 1.21A 2bxeB-1e6zA:
undetectable		 2bxeB-1e6zA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		6 / 12 GLY A 218
ALA A 217
ASP A 215
GLY A 293
THR A 365
PRO A 366
 None
None
NGO  A 502 ( 3.1A)
None
None
None
 1.33A 2nmyA-1e6zA:
undetectable		 2nmyA-1e6zA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 9 TYR A  10
PHE A  51
GLY A  96
ASP A 142
GLU A 144
TYR A 214
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-3.5A)
 0.58A 2uy4A-1e6zA:
18.5		 2uy4A-1e6zA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 7 PRO A 445
GLY A 446
LEU A 243
PHE A 259
 None
 0.89A 2vl2B-1e6zA:
undetectable		 2vl2B-1e6zA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 12 GLY A 442
TYR A 196
LEU A 199
VAL A 280
SER A 282
 None
 1.35A 2vqyA-1e6zA:
0.0		 2vqyA-1e6zA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 11 TYR A  10
PHE A  51
GLY A  96
ASP A 142
GLU A 144
TYR A 214
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-3.5A)
 0.87A 2xtkA-1e6zA:
19.7		 2xtkA-1e6zA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 10 TYR A  10
PHE A  51
GLY A  96
ASP A 142
GLU A 144
TYR A 214
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-3.5A)
 0.68A 2xtkB-1e6zA:
19.5		 2xtkB-1e6zA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 7 GLY A   9
ASN A  48
ALA A   6
VAL A 286
 None
 0.77A 3a2qA-1e6zA:
0.0		 3a2qA-1e6zA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 7 TRP A  97
GLY A 187
TRP A 220
ARG A 294
 NAG  A 503 ( 3.7A)
None
NAG  A 504 (-3.6A)
NAG  A 503 ( 4.9A)
 1.12A 3arrA-1e6zA:
33.5		 3arrA-1e6zA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 7 TRP A  97
GLY A 188
ASP A 215
TRP A 220
ARG A 294
 NAG  A 503 ( 3.7A)
NAG  A 504 ( 4.9A)
NGO  A 502 ( 3.1A)
NAG  A 504 (-3.6A)
NAG  A 503 ( 4.9A)
 0.82A 3arrA-1e6zA:
33.5		 3arrA-1e6zA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 7 GLY A 188
ASP A 215
TRP A 220
ARG A 294
 NAG  A 504 ( 4.9A)
NGO  A 502 ( 3.1A)
NAG  A 504 (-3.6A)
NAG  A 503 ( 4.9A)
 0.64A 3aruA-1e6zA:
33.5		 3aruA-1e6zA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 12 GLN A 344
GLY A 412
LEU A 415
ASP A 408
SER A 341
 None
 1.24A 3d91A-1e6zA:
undetectable		 3d91A-1e6zA:
21.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 11 TYR A  10
PHE A  51
GLY A  96
ASP A 142
TYR A 214
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-4.5A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.78A 3g6mA-1e6zA:
5.4		 3g6mA-1e6zA:
31.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		9 / 11 TYR A  10
PHE A  51
GLY A  96
GLU A 144
MET A 212
TYR A 214
ASP A 215
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.40A 3g6mA-1e6zA:
5.4		 3g6mA-1e6zA:
31.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 11 TYR A  10
PHE A  51
GLY A  96
TRP A  97
ASP A 142
TYR A 214
TYR A 292
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NAG  A 503 ( 3.7A)
NGO  A 502 (-3.1A)
NGO  A 502 (-4.5A)
NGO  A 502 (-4.8A)
 0.97A 3g6mA-1e6zA:
5.4		 3g6mA-1e6zA:
31.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		9 / 11 TYR A  10
PHE A  51
GLY A  96
TRP A  97
GLU A 144
MET A 212
TYR A 214
ASP A 215
TYR A 292
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NAG  A 503 ( 3.7A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
 0.62A 3g6mA-1e6zA:
5.4		 3g6mA-1e6zA:
31.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA427_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 5 TRP A  97
TYR A 145
MET A 212
ASP A 215
TRP A 220
 NAG  A 503 ( 3.7A)
None
NGO  A 502 (-3.4A)
NGO  A 502 ( 3.1A)
NAG  A 504 (-3.6A)
 0.78A 3g6mA-1e6zA:
5.4		 3g6mA-1e6zA:
31.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 12 VAL A 377
TRP A 324
ILE A 339
ALA A 340
LEU A 345
 None
 1.06A 3n8zB-1e6zA:
0.0		 3n8zB-1e6zA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 8 GLY A 138
LEU A 181
LEU A 165
ILE A 161
 None
 0.91A 3nbqB-1e6zA:
0.0		 3nbqB-1e6zA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 8 GLY A 138
LEU A 181
LEU A 165
ILE A 161
 None
 0.86A 3nbqC-1e6zA:
0.0		 3nbqC-1e6zA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 6 ILE A 183
PRO A 205
LEU A 206
ASP A 140
 None
 1.28A 3oi8A-1e6zA:
undetectable		 3oi8A-1e6zA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 8 GLY A 138
MET A 131
GLY A 135
ILE A  90
VAL A  75
 None
 1.32A 3v1nA-1e6zA:
undetectable		 3v1nA-1e6zA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		11 / 11 PHE A  51
GLY A  96
TRP A  97
ASP A 142
GLU A 144
MET A 212
TYR A 214
ASP A 215
TYR A 292
ARG A 294
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NAG  A 503 ( 3.7A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NAG  A 503 ( 4.9A)
NGO  A 502 (-3.5A)
 0.51A 3wqvA-1e6zA:
41.6		 3wqvA-1e6zA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		11 / 11 PHE A  51
GLY A  96
TRP A  97
ASP A 142
GLU A 144
MET A 212
TYR A 214
ASP A 215
TYR A 292
ARG A 294
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NAG  A 503 ( 3.7A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NAG  A 503 ( 4.9A)
NGO  A 502 (-3.5A)
 0.53A 3wqwA-1e6zA:
41.6		 3wqwA-1e6zA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 8 TYR A 195
ILE A 202
GLY A 153
PHE A 154
 None
 0.89A 4iqqD-1e6zA:
0.0		 4iqqD-1e6zA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 5 THR A  15
THR A  66
ASP A  63
TYR A  99
 None
 1.50A 4oltA-1e6zA:
0.0		 4oltA-1e6zA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 1e6z CHITINASE B
(Serratia
marcescens) 		3 / 3 LEU A 405
MET A 401
TYR A 342
 None
 0.86A 4p6xG-1e6zA:
0.0		 4p6xG-1e6zA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 12 ILE A  47
LEU A  44
ASP A 408
LEU A 415
PHE A  31
 None
 1.34A 4pbhA-1e6zA:
0.5		 4pbhA-1e6zA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 5 THR A  15
THR A  66
ASP A  63
TYR A  99
 None
 1.49A 4qwpA-1e6zA:
0.0		 4qwpA-1e6zA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 5 THR A  15
THR A  66
ASP A  63
TYR A  99
 None
 1.47A 4qwpB-1e6zA:
0.0		 4qwpB-1e6zA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		3 / 3 VAL A  74
LEU A  78
VAL A  33
 None
 0.58A 4wq4A-1e6zA:
0.5		 4wq4A-1e6zA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 4 PHE A  51
ASP A 140
GLY A  96
SER A  93
 NGO  A 502 (-4.7A)
None
NGO  A 502 ( 3.8A)
None
 1.39A 4xp9C-1e6zA:
0.0		 4xp9C-1e6zA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		3 / 3 TRP A  97
GLU A 144
ASP A 215
 NAG  A 503 ( 3.7A)
NGO  A 502 (-3.4A)
NGO  A 502 ( 3.1A)
 0.35A 5gqbA-1e6zA:
34.8		 5gqbA-1e6zA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		8 / 8 PHE A  51
GLY A  96
TRP A  97
GLU A 144
TYR A 214
ASP A 215
ARG A 294
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NAG  A 503 ( 3.7A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NAG  A 503 ( 4.9A)
NGO  A 502 (-3.5A)
 0.42A 5gqbA-1e6zA:
34.8		 5gqbA-1e6zA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 12 LEU A 192
LEU A 397
ILE A 285
GLY A 446
PRO A 445
 None
 1.16A 5ienA-1e6zA:
0.0		 5ienA-1e6zA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 5 TYR A  10
GLY A   9
GLY A 279
LEU A 211
 NGO  A 502 (-3.2A)
None
None
None
 0.71A 5jlcA-1e6zA:
0.0		 5jlcA-1e6zA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		3 / 3 ALA A 217
GLN A 306
THR A 378
 None
 0.76A 5n0oA-1e6zA:
0.0		 5n0oA-1e6zA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 7 LEU A  58
ALA A  61
LEU A  52
TRP A  62
 None
 1.08A 5nwvA-1e6zA:
0.0		 5nwvA-1e6zA:
6.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 1e6z CHITINASE B
(Serratia
marcescens) 		3 / 3 ARG A  89
PRO A 178
TYR A 208
 None
 1.02A 5tzoB-1e6zA:
undetectable		 5tzoB-1e6zA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 10 ILE A 202
LEU A 199
LEU A 243
ALA A 246
LEU A 248
 None
 1.19A 5y7pB-1e6zA:
0.0		 5y7pB-1e6zA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 10 ILE A 202
LEU A 199
LEU A 243
ALA A 246
LEU A 248
 None
 1.25A 5y7pD-1e6zA:
0.0		 5y7pD-1e6zA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 10 ILE A 202
LEU A 199
LEU A 243
ALA A 246
LEU A 248
 None
 1.20A 5y7pH-1e6zA:
0.0		 5y7pH-1e6zA:
21.85