SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1e7n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 1e7n BETA-CRYSTALLIN B2
(Mus
musculus) 		4 / 5 VAL A  43
GLY A  44
VAL A  56
TRP A  68
 None
 1.26A 1tkqB-1e7nA:
undetectable		 1tkqB-1e7nA:
6.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 1e7n BETA-CRYSTALLIN B2
(Mus
musculus) 		5 / 10 TYR A  62
VAL A  37
GLY A  60
VAL A  43
GLN A  54
 None
 1.28A 3km6A-1e7nA:
undetectable		 3km6A-1e7nA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 1e7n BETA-CRYSTALLIN B2
(Mus
musculus) 		5 / 9 TYR A  62
VAL A  37
GLY A  60
VAL A  43
GLN A  54
 None
 1.28A 3kmoA-1e7nA:
undetectable		 3kmoA-1e7nA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 1e7n BETA-CRYSTALLIN B2
(Mus
musculus) 		4 / 8 TYR A  62
VAL A  37
GLY A  60
GLY A  40
 None
 0.80A 3n9jB-1e7nA:
undetectable		 3n9jB-1e7nA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 1e7n BETA-CRYSTALLIN B2
(Mus
musculus) 		4 / 7 ILE A   3
HIS A  16
LEU A  25
ALA A  32
 None
 0.99A 5hrqE-1e7nA:
undetectable
5hrqF-1e7nA:
undetectable
5hrqJ-1e7nA:
undetectable		 5hrqE-1e7nA:
11.83
5hrqF-1e7nA:
16.83
5hrqJ-1e7nA:
16.83