SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1e8j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UCJ_A_AZMA229_1 (CARBONIC ANHYDRASE)	1e8j	RUBREDOXIN (Desulfovibrio gigas)	5 / 10	CYH A 6 VAL A 8 CYH A 39 GLY A 43 ALA A 44	None	1.21A	3ucjA-1e8jA: undetectable	3ucjA-1e8jA: 12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UCJ_A_AZMA229_1 (CARBONIC ANHYDRASE)	1e8j	RUBREDOXIN (Desulfovibrio gigas)	5 / 10	CYH A 9 VAL A 8 CYH A 39 GLY A 43 ALA A 44	None	1.12A	3ucjA-1e8jA: undetectable	3ucjA-1e8jA: 12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UCJ_B_AZMB229_2 (CARBONIC ANHYDRASE)	1e8j	RUBREDOXIN (Desulfovibrio gigas)	5 / 10	CYH A 6 VAL A 8 CYH A 39 GLY A 43 ALA A 44	None	1.21A	3ucjB-1e8jA: undetectable	3ucjB-1e8jA: 12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UCJ_B_AZMB229_2 (CARBONIC ANHYDRASE)	1e8j	RUBREDOXIN (Desulfovibrio gigas)	5 / 10	CYH A 9 VAL A 8 CYH A 39 GLY A 43 ALA A 44	None	1.13A	3ucjB-1e8jA: undetectable	3ucjB-1e8jA: 12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X23_A_LSNA503_1 (CYTOCHROME P450 2C9)	1e8j	RUBREDOXIN (Desulfovibrio gigas)	4 / 5	PRO A 26 GLY A 27 THR A 28 LYS A 29	None	1.10A	5x23A-1e8jA: undetectable	5x23A-1e8jA: 14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XXI_A_LSNA502_1 (CYTOCHROME P450 2C9)	1e8j	RUBREDOXIN (Desulfovibrio gigas)	4 / 6	PRO A 26 GLY A 27 THR A 28 LYS A 29	None	1.03A	5xxiA-1e8jA: undetectable	5xxiA-1e8jA: 7.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3UCJ_A_AZMA229_1","CARBONIC ANHYDRASE","1e8j","RUBREDOXIN","Desulfovibrio gigas",5,"CYH A   6;VAL A   8;CYH A  39;GLY A  43;ALA A  44","None","1.21A","3ucjA-1e8jA:undetectable","3ucjA-1e8jA:12.39"],["3UCJ_A_AZMA229_1","CARBONIC ANHYDRASE","1e8j","RUBREDOXIN","Desulfovibrio gigas",5,"CYH A   9;VAL A   8;CYH A  39;GLY A  43;ALA A  44","None","1.12A","3ucjA-1e8jA:undetectable","3ucjA-1e8jA:12.39"],["3UCJ_B_AZMB229_2","CARBONIC ANHYDRASE","1e8j","RUBREDOXIN","Desulfovibrio gigas",5,"CYH A   6;VAL A   8;CYH A  39;GLY A  43;ALA A  44","None","1.21A","3ucjB-1e8jA:undetectable","3ucjB-1e8jA:12.39"],["3UCJ_B_AZMB229_2","CARBONIC ANHYDRASE","1e8j","RUBREDOXIN","Desulfovibrio gigas",5,"CYH A   9;VAL A   8;CYH A  39;GLY A  43;ALA A  44","None","1.13A","3ucjB-1e8jA:undetectable","3ucjB-1e8jA:12.39"],["5X23_A_LSNA503_1","CYTOCHROME P450 2C9","1e8j","RUBREDOXIN","Desulfovibrio gigas",4,"PRO A  26;GLY A  27;THR A  28;LYS A  29","None","1.10A","5x23A-1e8jA:undetectable","5x23A-1e8jA:14.10"],["5XXI_A_LSNA502_1","CYTOCHROME P450 2C9","1e8j","RUBREDOXIN","Desulfovibrio gigas",4,"PRO A  26;GLY A  27;THR A  28;LYS A  29","None","1.03A","5xxiA-1e8jA:undetectable","5xxiA-1e8jA:7.21"]]