SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1e8t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 11 THR A 188
THR A 243
LEU A 206
GLY A 273
VAL A 312
 None
 1.06A 1akdA-1e8tA:
undetectable		 1akdA-1e8tA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 LEU A 499
ALA A 524
PRO A 176
THR A 173
TYR A 187
 None
 1.08A 1cbrA-1e8tA:
undetectable		 1cbrA-1e8tA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 LEU A 499
ALA A 524
PRO A 176
THR A 173
TYR A 187
 None
 1.08A 1cbrB-1e8tA:
undetectable		 1cbrB-1e8tA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 TYR A 262
VAL A 296
GLY A 318
GLY A 319
 None
 0.82A 1ekjE-1e8tA:
0.0
1ekjF-1e8tA:
0.0		 1ekjE-1e8tA:
17.65
1ekjF-1e8tA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 11 LEU A 492
LEU A 561
ALA A 546
SER A 529
THR A 527
 None
 1.06A 1ictA-1e8tA:
0.0
1ictC-1e8tA:
0.0		 1ictA-1e8tA:
15.56
1ictC-1e8tA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 4 GLY A 246
LEU A 245
GLY A 276
ARG A 274
 None
 1.43A 1j7kA-1e8tA:
0.0		 1j7kA-1e8tA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.05A 1kifA-1e8tA:
undetectable		 1kifA-1e8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.06A 1kifB-1e8tA:
undetectable		 1kifB-1e8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.06A 1kifC-1e8tA:
undetectable		 1kifC-1e8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.05A 1kifD-1e8tA:
undetectable		 1kifD-1e8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.05A 1kifE-1e8tA:
undetectable		 1kifE-1e8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.05A 1kifF-1e8tA:
undetectable		 1kifF-1e8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.05A 1kifG-1e8tA:
undetectable		 1kifG-1e8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.05A 1kifH-1e8tA:
undetectable		 1kifH-1e8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 SER A 237
SER A 239
VAL A 316
PHE A 314
 None
 1.14A 1oipA-1e8tA:
undetectable		 1oipA-1e8tA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 THR A 471
THR A 527
SER A 544
VAL A 563
 None
 1.10A 1tv8A-1e8tA:
undetectable		 1tv8A-1e8tA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 THR A 471
THR A 527
SER A 544
VAL A 563
 None
 1.19A 1tv8B-1e8tA:
undetectable		 1tv8B-1e8tA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		3 / 3 THR A 396
PRO A 392
THR A 394
 None
 0.86A 1unjF-1e8tA:
undetectable		 1unjF-1e8tA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		3 / 3 THR A 396
PRO A 392
THR A 394
 None
 0.87A 1unmE-1e8tA:
undetectable		 1unmE-1e8tA:
5.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3E_A_ZMRA1200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 10 GLU A 258
TYR A 317
PHE A 364
GLU A 401
ARG A 416
ARG A 498
 None
 0.96A 1v3eA-1e8tA:
49.1		 1v3eA-1e8tA:
31.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3E_A_ZMRA1200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 10 GLU A 258
TYR A 317
PHE A 364
GLU A 401
ARG A 416
TYR A 526
 None
 0.70A 1v3eA-1e8tA:
49.1		 1v3eA-1e8tA:
31.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3E_A_ZMRA1200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 10 TYR A 299
TYR A 317
PHE A 364
GLU A 401
ARG A 416
ARG A 498
 None
 0.82A 1v3eA-1e8tA:
49.1		 1v3eA-1e8tA:
31.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3E_A_ZMRA1200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 10 TYR A 299
TYR A 317
PHE A 364
GLU A 401
ARG A 416
TYR A 526
 None
 0.48A 1v3eA-1e8tA:
49.1		 1v3eA-1e8tA:
31.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3E_B_ZMRB2200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 10 GLU A 258
TYR A 317
PHE A 364
GLU A 401
ARG A 416
ARG A 498
 None
 0.99A 1v3eB-1e8tA:
49.1		 1v3eB-1e8tA:
31.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3E_B_ZMRB2200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 10 GLU A 258
TYR A 317
PHE A 364
GLU A 401
ARG A 416
TYR A 526
 None
 0.75A 1v3eB-1e8tA:
49.1		 1v3eB-1e8tA:
31.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3E_B_ZMRB2200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 10 TYR A 299
TYR A 317
PHE A 364
GLU A 401
ARG A 416
ARG A 498
 None
 0.87A 1v3eB-1e8tA:
49.1		 1v3eB-1e8tA:
31.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3E_B_ZMRB2200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 10 TYR A 299
TYR A 317
PHE A 364
GLU A 401
ARG A 416
TYR A 526
 None
 0.58A 1v3eB-1e8tA:
49.1		 1v3eB-1e8tA:
31.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.06A 1ve9A-1e8tA:
undetectable		 1ve9A-1e8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 11 THR A 188
THR A 243
LEU A 206
GLY A 273
VAL A 312
 None
 1.05A 2a1nA-1e8tA:
undetectable		 2a1nA-1e8tA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 10 THR A 188
THR A 243
LEU A 206
GLY A 273
VAL A 312
 None
 1.07A 2cp4A-1e8tA:
0.0		 2cp4A-1e8tA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.05A 2du8G-1e8tA:
undetectable		 2du8G-1e8tA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 GLU A 258
TYR A 317
GLU A 401
ARG A 416
TYR A 526
 None
 0.77A 2f0zA-1e8tA:
29.1		 2f0zA-1e8tA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F10_A_BCZA382_0
(SIALIDASE 2)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ILE A 175
TYR A 317
GLU A 401
ARG A 416
TYR A 526
 None
 0.66A 2f10A-1e8tA:
28.0		 2f10A-1e8tA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 THR A 471
THR A 527
SER A 544
VAL A 563
 None
 1.11A 2fb2A-1e8tA:
undetectable		 2fb2A-1e8tA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 THR A 471
THR A 527
SER A 544
VAL A 563
 None
 1.09A 2fb2B-1e8tA:
undetectable		 2fb2B-1e8tA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 PHE A 162
ILE A 558
ALA A 546
THR A 490
GLU A 158
 None
 1.12A 2j0dA-1e8tA:
0.0		 2j0dA-1e8tA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 6 SER A 324
VAL A 390
ASP A 294
TRP A 295
 None
 1.14A 2x45A-1e8tA:
0.2		 2x45A-1e8tA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 SER A 324
VAL A 390
ASP A 294
TRP A 295
 None
 1.16A 2x45B-1e8tA:
0.2		 2x45B-1e8tA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 SER A 324
VAL A 390
ASP A 294
TRP A 295
 None
 1.14A 2x45C-1e8tA:
0.2		 2x45C-1e8tA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLN A 371
SER A 315
TYR A 414
SER A 239
 None
 1.27A 2xz5C-1e8tA:
0.0
2xz5D-1e8tA:
0.0		 2xz5C-1e8tA:
17.84
2xz5D-1e8tA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		3 / 3 THR A 396
PRO A 392
THR A 394
 None
 0.87A 316dC-1e8tA:
undetectable		 316dC-1e8tA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 SER A 324
VAL A 390
ASP A 294
TRP A 295
 None
 1.16A 3bu1A-1e8tA:
0.2		 3bu1A-1e8tA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 PRO A 267
SER A 239
ASP A 248
ILE A 376
LEU A 286
 None
 1.25A 3iv6A-1e8tA:
undetectable		 3iv6A-1e8tA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 PRO A 267
SER A 239
ASP A 248
ILE A 376
LEU A 286
 None
 1.26A 3iv6C-1e8tA:
undetectable		 3iv6C-1e8tA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 6 ILE A 548
ALA A 524
THR A 527
THR A 490
 None
 1.13A 3mdrA-1e8tA:
undetectable		 3mdrA-1e8tA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLY A 468
TYR A 470
ALA A 400
SER A 418
 None
 0.76A 3u9hA-1e8tA:
undetectable		 3u9hA-1e8tA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLY A 468
TYR A 470
ALA A 400
SER A 418
 None
 0.77A 3u9hB-1e8tA:
undetectable		 3u9hB-1e8tA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		3 / 3 ASN A 298
TRP A 295
ASP A 261
 None
None
CA  A1001 (-3.6A)
 1.26A 4a7tA-1e8tA:
0.0
4a7tF-1e8tA:
0.0		 4a7tA-1e8tA:
17.34
4a7tF-1e8tA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 6 PHE A 220
TYR A 185
HIS A 184
PHE A 221
 None
None
GOL  A1002 (-4.1A)
None
 1.01A 4a97E-1e8tA:
0.0		 4a97E-1e8tA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLY A 468
TYR A 470
ALA A 400
SER A 418
 None
 0.80A 4bjcA-1e8tA:
undetectable		 4bjcA-1e8tA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 LEU A 561
ALA A 546
SER A 529
THR A 527
 None
 0.68A 4d7bA-1e8tA:
undetectable		 4d7bA-1e8tA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 LEU A 561
PHE A 156
VAL A 563
ALA A 546
THR A 527
 None
 1.12A 4fiaA-1e8tA:
0.0		 4fiaA-1e8tA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 LEU A 561
PHE A 156
VAL A 563
ALA A 546
THR A 527
 None
 1.12A 4fiaA-1e8tA:
0.0		 4fiaA-1e8tA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 GLY A 468
TYR A 470
ALA A 400
SER A 418
 None
 0.83A 4hyfA-1e8tA:
undetectable		 4hyfA-1e8tA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLY A 468
TYR A 470
ALA A 400
SER A 418
 None
 0.84A 4hyfB-1e8tA:
undetectable		 4hyfB-1e8tA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLY A 468
TYR A 470
ALA A 400
SER A 418
 None
 0.81A 4hyfC-1e8tA:
undetectable		 4hyfC-1e8tA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 6 LEU A 561
ALA A 546
SER A 529
THR A 527
 None
 0.74A 4ikiB-1e8tA:
undetectable		 4ikiB-1e8tA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 LEU A 561
ALA A 546
SER A 529
THR A 527
 None
 0.69A 4ikjA-1e8tA:
undetectable
4ikjB-1e8tA:
undetectable		 4ikjA-1e8tA:
15.56
4ikjB-1e8tA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 LEU A 561
ALA A 546
SER A 529
THR A 527
 None
 0.69A 4ikjA-1e8tA:
0.0
4ikjB-1e8tA:
0.0		 4ikjA-1e8tA:
15.56
4ikjB-1e8tA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 LEU A 561
ALA A 546
SER A 529
THR A 527
 None
 0.73A 4ikkA-1e8tA:
undetectable
4ikkB-1e8tA:
undetectable		 4ikkA-1e8tA:
15.56
4ikkB-1e8tA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 281
THR A 168
LEU A 193
THR A 232
 None
 1.47A 4mbsB-1e8tA:
undetectable		 4mbsB-1e8tA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 GLY A 366
LEU A 388
PHE A 292
ASP A 327
 None
 0.88A 5hieB-1e8tA:
undetectable		 5hieB-1e8tA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 1e8t HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 PHE A 178
LEU A 211
VAL A 534
THR A 528
GLU A 158
 None
 1.49A 5v1tA-1e8tA:
undetectable		 5v1tA-1e8tA:
20.04