SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1e96'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 1e96 NEUTROPHIL CYTOSOL
FACTOR 2 (NCF-2) TPR
DOMAIN, RESIDUES
1-203
(Homo
sapiens) 		4 / 6 ILE B  91
LYS B 134
LYS B 133
ALA B 132
 None
 1.15A 1hk2A-1e96B:
1.4		 1hk2A-1e96B:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 1e96 NEUTROPHIL CYTOSOL
FACTOR 2 (NCF-2) TPR
DOMAIN, RESIDUES
1-203
(Homo
sapiens) 		5 / 9 ILE B 177
CYH B  45
PHE B  29
PHE B 183
GLY B 113
 None
 1.37A 3ko0A-1e96B:
undetectable
3ko0C-1e96B:
undetectable		 3ko0A-1e96B:
17.77
3ko0C-1e96B:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 1e96 NEUTROPHIL CYTOSOL
FACTOR 2 (NCF-2) TPR
DOMAIN, RESIDUES
1-203
(Homo
sapiens) 		5 / 10 PHE B 183
GLY B 113
ILE B 177
CYH B  45
PHE B  29
 None
 1.42A 3ko0L-1e96B:
undetectable
3ko0N-1e96B:
undetectable		 3ko0L-1e96B:
17.77
3ko0N-1e96B:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 1e96 NEUTROPHIL CYTOSOL
FACTOR 2 (NCF-2) TPR
DOMAIN, RESIDUES
1-203
(Homo
sapiens) 		5 / 8 PHE B 183
GLY B 113
ILE B 177
CYH B  45
PHE B  29
 None
 1.39A 3ko0O-1e96B:
undetectable
3ko0Q-1e96B:
0.0		 3ko0O-1e96B:
17.77
3ko0Q-1e96B:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 1e96 NEUTROPHIL CYTOSOL
FACTOR 2 (NCF-2) TPR
DOMAIN, RESIDUES
1-203
(Homo
sapiens) 		5 / 10 ILE B 177
CYH B  45
PHE B  29
PHE B 183
GLY B 113
 None
 1.36A 3ko0R-1e96B:
undetectable
3ko0T-1e96B:
undetectable		 3ko0R-1e96B:
17.77
3ko0T-1e96B:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1e96 NEUTROPHIL CYTOSOL
FACTOR 2 (NCF-2) TPR
DOMAIN, RESIDUES
1-203
(Homo
sapiens) 		3 / 3 PHE B 119
CYH B 121
HIS B 156
 None
 1.32A 3u9fL-1e96B:
undetectable		 3u9fL-1e96B:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1e96 NEUTROPHIL CYTOSOL
FACTOR 2 (NCF-2) TPR
DOMAIN, RESIDUES
1-203
(Homo
sapiens) 		3 / 3 PHE B 119
CYH B 121
HIS B 156
 None
 1.24A 3u9fS-1e96B:
undetectable		 3u9fS-1e96B:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 1e96 NEUTROPHIL CYTOSOL
FACTOR 2 (NCF-2) TPR
DOMAIN, RESIDUES
1-203
(Homo
sapiens) 		4 / 7 ILE B 127
MET B  79
ALA B  90
ILE B  91
 None
 0.81A 4y03A-1e96B:
undetectable		 4y03A-1e96B:
20.59