SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ear'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KI7_B_ID2B2_0 (THYMIDINE KINASE)	1ear	UREASE ACCESSORY PROTEIN UREE (Sporosarcina pasteurii)	5 / 12	ILE A 122 ILE A 81 MET A 92 ARG A 99 GLU A 119	None	1.39A	1ki7B-1earA: undetectable	1ki7B-1earA: 15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCB_P_DHIP3_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-L-GLN-D-PHE -L-HIS-D-PRO-OH)	1ear	UREASE ACCESSORY PROTEIN UREE (Sporosarcina pasteurii)	4 / 5	TYR A 129 TYR A 114 GLU A 119 GLN A 131	None	1.24A	1mcbA-1earA: 0.0 1mcbB-1earA: 0.0 1mcbP-1earA: undetectable	1mcbA-1earA: 20.72 1mcbB-1earA: 20.72 1mcbP-1earA: 2.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_H_ACTH504_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	1ear	UREASE ACCESSORY PROTEIN UREE (Sporosarcina pasteurii)	3 / 3	LYS A 74 GLU A 76 TRP A 27	None	1.08A	3v4tH-1earA: 0.0	3v4tH-1earA: 15.04