SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eav'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 1eav MOLYBDOPTERIN
BIOSYNTHESIS CNX1
PROTEIN
(Arabidopsis
thaliana) 		5 / 9 GLY A 103
LEU A 133
LEU A 151
LEU A 105
ILE A 135
 None
 1.06A 3wdmC-1eavA:
undetectable		 3wdmC-1eavA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 1eav MOLYBDOPTERIN
BIOSYNTHESIS CNX1
PROTEIN
(Arabidopsis
thaliana) 		4 / 6 PRO A 138
GLY A 139
ASN A 142
GLU A 146
 None
 1.01A 3zqtA-1eavA:
0.0		 3zqtA-1eavA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1eav MOLYBDOPTERIN
BIOSYNTHESIS CNX1
PROTEIN
(Arabidopsis
thaliana) 		4 / 4 ASN A 140
SER A 112
ALA A 143
VAL A 144
 None
 1.00A 4x1kC-1eavA:
undetectable		 4x1kC-1eavA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1eav MOLYBDOPTERIN
BIOSYNTHESIS CNX1
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 SER A  26
ALA A  30
VAL A  33
 None
 0.67A 4x20C-1eavA:
2.5		 4x20C-1eavA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 1eav MOLYBDOPTERIN
BIOSYNTHESIS CNX1
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 LEU A  63
ASP A  68
ILE A 135
 None
 0.66A 4xi3D-1eavA:
undetectable		 4xi3D-1eavA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1eav MOLYBDOPTERIN
BIOSYNTHESIS CNX1
PROTEIN
(Arabidopsis
thaliana) 		4 / 4 ASN A 140
SER A 112
ALA A 143
VAL A 144
 None
 1.08A 5nm5A-1eavA:
undetectable		 5nm5A-1eavA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 1eav MOLYBDOPTERIN
BIOSYNTHESIS CNX1
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 ILE A 162
LEU A  63
LEU A 105
PRO A 102
THR A 101
 None
 1.22A 5xxiA-1eavA:
undetectable		 5xxiA-1eavA:
17.06