SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ebl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 11 HIS A 244
TRP A 310
LEU A 189
GLY A 306
VAL A 212
 COA  A1350 (-4.4A)
None
COA  A1350 ( 4.8A)
None
None
 1.44A 1axwB-1eblA:
undetectable		 1axwB-1eblA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 6 LEU A 142
MET A 207
LEU A 189
HIS A 244
 None
COA  A1350 (-2.9A)
COA  A1350 ( 4.8A)
COA  A1350 (-4.4A)
 1.12A 1errB-1eblA:
0.0		 1errB-1eblA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 7 LEU A 298
GLN A 297
PHE A 317
LEU A 314
 None
 1.09A 1v55C-1eblA:
undetectable
1v55J-1eblA:
undetectable		 1v55C-1eblA:
21.30
1v55J-1eblA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 12 ILE A 174
VAL A 315
LEU A 301
VAL A 299
LEU A 284
 None
 0.97A 2aw1A-1eblA:
undetectable		 2aw1A-1eblA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 7 LEU A 298
GLN A 297
PHE A 317
LEU A 314
 None
 1.07A 2eimC-1eblA:
undetectable
2eimJ-1eblA:
undetectable		 2eimC-1eblA:
21.30
2eimJ-1eblA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 7 ALA A 255
THR A 254
ALA A 253
PRO A 243
 None
 0.83A 2ql8A-1eblA:
0.0
2ql8B-1eblA:
0.0		 2ql8A-1eblA:
19.48
2ql8B-1eblA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 8 ALA A  79
SER A 139
GLY A  55
ALA A  90
 None
 0.90A 2vh3B-1eblA:
undetectable		 2vh3B-1eblA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 11 GLY A 152
THR A  37
ILE A  33
LEU A  22
THR A  28
 COA  A1350 (-3.7A)
COA  A1350 (-4.6A)
None
None
None
 1.01A 3bexC-1eblA:
undetectable
3bexD-1eblA:
0.0		 3bexC-1eblA:
23.08
3bexD-1eblA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 10 LEU A  22
THR A  28
GLY A 152
THR A  37
ILE A  33
 None
None
COA  A1350 (-3.7A)
COA  A1350 (-4.6A)
None
 1.01A 3bexC-1eblA:
undetectable
3bexD-1eblA:
undetectable		 3bexC-1eblA:
23.08
3bexD-1eblA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 10 GLY A 152
THR A  37
ILE A  33
LEU A  22
THR A  28
 COA  A1350 (-3.7A)
COA  A1350 (-4.6A)
None
None
None
 1.01A 3bexE-1eblA:
undetectable
3bexF-1eblA:
0.0		 3bexE-1eblA:
23.08
3bexF-1eblA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 11 LEU A  22
THR A  28
GLY A 152
THR A  37
ILE A  33
 None
None
COA  A1350 (-3.7A)
COA  A1350 (-4.6A)
None
 1.01A 3bexE-1eblA:
undetectable
3bexF-1eblA:
0.0		 3bexE-1eblA:
23.08
3bexF-1eblA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 11 GLY A 152
THR A  37
ILE A  33
LEU A  22
THR A  28
 COA  A1350 (-3.7A)
COA  A1350 (-4.6A)
None
None
None
 1.01A 3bf1A-1eblA:
undetectable
3bf1B-1eblA:
undetectable		 3bf1A-1eblA:
23.08
3bf1B-1eblA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 12 LEU A  22
THR A  28
GLY A 152
THR A  37
ILE A  33
 None
None
COA  A1350 (-3.7A)
COA  A1350 (-4.6A)
None
 1.04A 3bf1A-1eblA:
undetectable
3bf1B-1eblA:
undetectable		 3bf1A-1eblA:
23.08
3bf1B-1eblA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 11 GLY A 152
THR A  37
ILE A  33
LEU A  22
THR A  28
 COA  A1350 (-3.7A)
COA  A1350 (-4.6A)
None
None
None
 0.98A 3bf1C-1eblA:
undetectable
3bf1D-1eblA:
0.0		 3bf1C-1eblA:
23.08
3bf1D-1eblA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 11 LEU A  22
THR A  28
GLY A 152
THR A  37
ILE A  33
 None
None
COA  A1350 (-3.7A)
COA  A1350 (-4.6A)
None
 1.03A 3bf1C-1eblA:
undetectable
3bf1D-1eblA:
undetectable		 3bf1C-1eblA:
23.08
3bf1D-1eblA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 11 GLY A 152
THR A  37
ILE A  33
LEU A  22
THR A  28
 COA  A1350 (-3.7A)
COA  A1350 (-4.6A)
None
None
None
 1.00A 3bf1E-1eblA:
undetectable
3bf1F-1eblA:
0.0		 3bf1E-1eblA:
23.08
3bf1F-1eblA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 11 LEU A  22
THR A  28
GLY A 152
THR A  37
ILE A  33
 None
None
COA  A1350 (-3.7A)
COA  A1350 (-4.6A)
None
 1.01A 3bf1E-1eblA:
undetectable
3bf1F-1eblA:
undetectable		 3bf1E-1eblA:
23.08
3bf1F-1eblA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 6 HIS A 272
LEU A  12
ALA A  58
PRO A 281
 None
 1.10A 3gv1A-1eblA:
0.0
3gv1C-1eblA:
0.0		 3gv1A-1eblA:
19.18
3gv1C-1eblA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 6 LEU A  12
ALA A  58
PRO A 281
HIS A 272
 None
 1.07A 3gv1A-1eblA:
0.0
3gv1B-1eblA:
0.0		 3gv1A-1eblA:
19.18
3gv1B-1eblA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 12 GLY A 307
GLY A 183
ALA A 110
ALA A 111
LEU A 188
 None
 1.08A 3p2kC-1eblA:
undetectable		 3p2kC-1eblA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 12 GLY A 307
GLY A 183
ALA A 110
ALA A 111
LEU A 188
 None
 1.07A 3p2kD-1eblA:
undetectable		 3p2kD-1eblA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 12 LEU A  22
GLY A 158
GLY A 273
ILE A  39
ALA A 143
 None
 1.11A 3uj7B-1eblA:
undetectable		 3uj7B-1eblA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 6 GLY A   9
TYR A  11
ALA A  62
GLU A  57
 None
 0.95A 4ae1A-1eblA:
undetectable		 4ae1A-1eblA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 10 ALA A 313
LEU A 301
ILE A 293
ALA A 287
THR A   8
 None
 0.98A 4j14A-1eblA:
undetectable		 4j14A-1eblA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 5 VAL A 315
LEU A 284
VAL A 288
PHE A 317
 None
 0.91A 4lb0B-1eblA:
0.0		 4lb0B-1eblA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 12 GLY A 152
THR A  37
ILE A  33
LEU A  22
THR A  28
 COA  A1350 (-3.7A)
COA  A1350 (-4.6A)
None
None
None
 0.98A 4o5fA-1eblA:
undetectable
4o5fB-1eblA:
undetectable		 4o5fA-1eblA:
25.45
4o5fB-1eblA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 12 LEU A  22
THR A  28
GLY A 152
THR A  37
ILE A  33
 None
None
COA  A1350 (-3.7A)
COA  A1350 (-4.6A)
None
 1.00A 4o5fA-1eblA:
undetectable
4o5fB-1eblA:
undetectable		 4o5fA-1eblA:
25.45
4o5fB-1eblA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 12 HIS A 244
ALA A 246
GLY A 306
GLY A 311
LEU A 220
 COA  A1350 (-4.4A)
COA  A1350 ( 3.7A)
None
None
None
 1.11A 4uilH-1eblA:
undetectable
4uilL-1eblA:
undetectable		 4uilH-1eblA:
20.94
4uilL-1eblA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 8 ALA A  90
ALA A  91
ILE A  94
LEU A 135
 None
 0.67A 4v1fA-1eblA:
undetectable
4v1fB-1eblA:
undetectable		 4v1fA-1eblA:
12.89
4v1fB-1eblA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		3 / 3 VAL A 242
LEU A 301
VAL A 280
 None
 0.63A 4wq4A-1eblA:
2.1		 4wq4A-1eblA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 9 SER A 279
ALA A 283
GLU A 286
ILE A  39
 None
 0.97A 4xtaA-1eblA:
0.0		 4xtaA-1eblA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 5 LEU A 189
ALA A 246
ASN A 247
ILE A 250
 COA  A1350 ( 4.8A)
COA  A1350 ( 3.7A)
COA  A1350 (-2.8A)
COA  A1350 (-3.2A)
 0.94A 4y03B-1eblA:
undetectable		 4y03B-1eblA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 12 GLY A 152
THR A  37
ILE A  33
LEU A  22
THR A  28
 COA  A1350 (-3.7A)
COA  A1350 (-4.6A)
None
None
None
 1.04A 5b8hA-1eblA:
undetectable
5b8hB-1eblA:
undetectable		 5b8hA-1eblA:
23.08
5b8hB-1eblA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 12 LEU A  22
THR A  28
GLY A 152
THR A  37
ILE A  33
 None
None
COA  A1350 (-3.7A)
COA  A1350 (-4.6A)
None
 1.05A 5b8hA-1eblA:
undetectable
5b8hB-1eblA:
undetectable		 5b8hA-1eblA:
23.08
5b8hB-1eblA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 8 SER A 279
ALA A 278
HIS A 244
LEU A 142
 None
None
COA  A1350 (-4.4A)
None
 1.02A 5dzkd-1eblA:
undetectable
5dzkr-1eblA:
undetectable		 5dzkd-1eblA:
21.18
5dzkr-1eblA:
1.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 8 SER A 279
ALA A 278
HIS A 244
LEU A 142
 None
None
COA  A1350 (-4.4A)
None
 1.02A 5dzkF-1eblA:
undetectable
5dzkT-1eblA:
undetectable		 5dzkF-1eblA:
21.18
5dzkT-1eblA:
1.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 8 THR A  81
SER A 276
GLY A 307
ALA A 113
 None
 0.93A 5eevL-1eblA:
undetectable
5eevV-1eblA:
undetectable		 5eevL-1eblA:
13.36
5eevV-1eblA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 8 THR A  81
SER A 276
GLY A 307
ALA A 113
 None
 0.93A 5eewL-1eblA:
undetectable
5eewV-1eblA:
undetectable		 5eewL-1eblA:
13.36
5eewV-1eblA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 8 THR A  81
SER A 276
GLY A 307
ALA A 113
 None
 0.93A 5ef3L-1eblA:
undetectable
5ef3V-1eblA:
undetectable		 5ef3L-1eblA:
13.36
5ef3V-1eblA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 7 VAL A 121
SER A 120
GLY A 114
VAL A 108
 None
 0.84A 5fpdB-1eblA:
1.5		 5fpdB-1eblA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_0
(METHYLTRANSFERASE)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		6 / 12 ALA A 113
GLY A 138
TYR A 117
ARG A  61
ALA A  58
ALA A 278
 None
 1.34A 5n5dA-1eblA:
undetectable		 5n5dA-1eblA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		4 / 7 LEU A 135
ALA A 163
ILE A   5
LEU A 166
 None
 0.94A 5te8C-1eblA:
0.0		 5te8C-1eblA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 12 VAL A 288
GLY A   9
ALA A  58
LEU A  98
LEU A 135
 None
 1.10A 5xxiA-1eblA:
undetectable		 5xxiA-1eblA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1ebl BETA-KETOACYL-ACP
SYNTHASE III
(Escherichia
coli) 		5 / 12 SER A  52
LEU A 135
VAL A 136
GLY A 138
SER A 139
 None
 1.25A 6a94A-1eblA:
undetectable		 6a94A-1eblA:
22.85