SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ebp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 1ebp EPO RECEPTOR
(Homo
sapiens) 		4 / 4 ALA A  72
ARG A  80
GLN A  71
GLU A  41
 None
 1.42A 1lqtB-1ebpA:
0.0		 1lqtB-1ebpA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 1ebp EPO RECEPTOR
(Homo
sapiens) 		4 / 4 ALA A  72
ARG A  80
GLN A  71
GLU A  41
 None
 1.41A 1lquB-1ebpA:
undetectable		 1lquB-1ebpA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 1ebp EPO RECEPTOR
(Homo
sapiens) 		4 / 8 PHE A 194
ALA A 129
ARG A 130
LEU A 218
 None
 0.92A 2bxkA-1ebpA:
undetectable		 2bxkA-1ebpA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_E_DVAE6_0
(VAL-GRAMICIDIN A)		 1ebp EPO RECEPTOR
(Homo
sapiens) 		4 / 4 ALA A 123
VAL A 196
TRP A 212
TRP A 142
 None
 1.49A 2y5mE-1ebpA:
undetectable
2y5mF-1ebpA:
undetectable		 2y5mE-1ebpA:
6.94
2y5mF-1ebpA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 1ebp EPO RECEPTOR
(Homo
sapiens) 		3 / 3 ALA A 102
VAL A 100
TRP A  40
 None
 0.86A 3l8lC-1ebpA:
undetectable
3l8lD-1ebpA:
undetectable		 3l8lC-1ebpA:
6.94
3l8lD-1ebpA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 1ebp EPO RECEPTOR
(Homo
sapiens) 		4 / 4 ASN A 164
ALA A 166
GLY A 163
THR A 190
 None
 1.00A 4bboC-1ebpA:
0.0		 4bboC-1ebpA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1ebp EPO RECEPTOR
(Homo
sapiens) 		4 / 5 TYR A 109
GLU A  24
GLU A  42
TYR A  53
 None
 1.34A 4twdH-1ebpA:
0.8
4twdI-1ebpA:
1.6		 4twdH-1ebpA:
22.46
4twdI-1ebpA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 1ebp EPO RECEPTOR
(Homo
sapiens) 		5 / 11 TYR A 192
VAL A 160
SER A 213
ALA A 123
VAL A 216
 None
 1.24A 6hu9A-1ebpA:
undetectable
6hu9E-1ebpA:
undetectable
6hu9I-1ebpA:
undetectable		 6hu9A-1ebpA:
18.96
6hu9E-1ebpA:
23.04
6hu9I-1ebpA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ebp EPO RECEPTOR
(Homo
sapiens) 		4 / 6 ILE A 174
ALA A 198
ARG A 155
MET A 200
 None
 1.05A 6hu9m-1ebpA:
undetectable
6hu9q-1ebpA:
undetectable		 6hu9m-1ebpA:
17.29
6hu9q-1ebpA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 1ebp EPO RECEPTOR
(Homo
sapiens) 		5 / 10 TYR A 192
VAL A 160
SER A 213
ALA A 123
VAL A 216
 None
 1.17A 6hu9L-1ebpA:
0.0
6hu9P-1ebpA:
0.0
6hu9T-1ebpA:
0.0		 6hu9L-1ebpA:
18.96
6hu9P-1ebpA:
23.04
6hu9T-1ebpA:
14.15