SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ecg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		6 / 12 LEU A 216
LEU A 213
ALA A 212
LEU A  23
ILE A  34
ILE A   6
 None
 1.29A 1crbA-1ecgA:
0.0		 1crbA-1ecgA:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 12 ILE A 308
LEU A 363
LEU A 282
ILE A 286
PHE A 436
 None
 1.20A 1fmlB-1ecgA:
0.0		 1fmlB-1ecgA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 12 ILE A 429
ALA A 431
TRP A 290
ALA A 387
ILE A 379
 None
 1.25A 1g5yB-1ecgA:
undetectable		 1g5yB-1ecgA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 11 ARG A 400
ILE A 425
ALA A 417
LEU A 415
ALA A 412
 None
 1.36A 1jb0B-1ecgA:
0.0		 1jb0B-1ecgA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 10 LEU A 253
ALA A 274
ILE A 308
GLY A 279
PRO A 397
 None
 1.04A 1k6cA-1ecgA:
undetectable		 1k6cA-1ecgA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 5 SER A 368
SER A 394
PHE A 254
PHE A 436
 PIN  A 506 ( 3.8A)
None
None
None
 1.42A 1oipA-1ecgA:
undetectable		 1oipA-1ecgA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		3 / 3 GLU A 203
THR A 202
LEU A 221
 None
 0.72A 1v8bC-1ecgA:
2.4		 1v8bC-1ecgA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		6 / 12 LEU A  98
ALA A 136
ASP A 140
ILE A 173
ALA A 171
ILE A  96
 None
 1.38A 2rkfB-1ecgA:
undetectable		 2rkfB-1ecgA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 8 ILE A 429
GLY A 372
LEU A 415
PHE A 436
 None
PIN  A 506 ( 3.4A)
None
None
 0.72A 2vctA-1ecgA:
0.0		 2vctA-1ecgA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A  63
ALA A  31
ALA A  99
VAL A 170
GLY A  68
 None
 1.14A 3c6gB-1ecgA:
undetectable		 3c6gB-1ecgA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 11 LEU A 104
GLN A  86
GLY A 102
CYH A   1
GLY A 406
 None
ONL  A 505 (-4.2A)
ONL  A 505 (-3.7A)
ONL  A 505 ( 1.8A)
ONL  A 505 ( 4.2A)
 1.12A 3gy3A-1ecgA:
undetectable		 3gy3A-1ecgA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 11 LEU A 104
SER A 126
GLY A 102
CYH A   1
GLY A 406
 None
ONL  A 505 (-2.7A)
ONL  A 505 (-3.7A)
ONL  A 505 ( 1.8A)
ONL  A 505 ( 4.2A)
 1.15A 3gy3A-1ecgA:
undetectable		 3gy3A-1ecgA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 12 ILE A  69
GLY A  70
ALA A  19
ALA A  31
ILE A   6
 None
 0.97A 3jayA-1ecgA:
0.0		 3jayA-1ecgA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 8 ILE A 407
CYH A 252
PHE A 456
PHE A 461
 None
 0.93A 3ko0B-1ecgA:
0.0
3ko0J-1ecgA:
0.0		 3ko0B-1ecgA:
15.00
3ko0J-1ecgA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 9 LEU A 213
PHE A 218
ILE A   6
ALA A   7
ALA A 180
 None
 1.18A 3mdtA-1ecgA:
0.0		 3mdtA-1ecgA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 6 VAL A  72
VAL A 170
ILE A  33
ARG A 261
 None
 1.09A 3mssA-1ecgA:
undetectable		 3mssA-1ecgA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 8 VAL A  12
GLY A   8
ILE A 232
GLY A  68
 None
 0.73A 3n9jB-1ecgA:
undetectable		 3n9jB-1ecgA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 9 GLY A 430
ALA A 431
ASP A 432
ILE A 378
LEU A 434
 None
 1.03A 3ogpB-1ecgA:
undetectable		 3ogpB-1ecgA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 12 GLY A 430
ALA A 431
ASP A 432
ILE A 378
LEU A 434
 None
 0.99A 3ogqB-1ecgA:
undetectable		 3ogqB-1ecgA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 8 PRO A 251
ILE A 269
ILE A 266
VAL A 446
 None
 0.78A 3p4wC-1ecgA:
0.0		 3p4wC-1ecgA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 11 ARG A 400
ILE A 425
ALA A 417
LEU A 415
ALA A 412
 None
 1.35A 3pcqB-1ecgA:
undetectable		 3pcqB-1ecgA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 7 GLY A 430
ALA A 431
ASP A 432
ILE A 378
 None
 0.75A 3t3cA-1ecgA:
undetectable		 3t3cA-1ecgA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		3 / 3 GLY A  65
THR A  35
ASN A  13
 None
 0.67A 3v4tD-1ecgA:
0.0		 3v4tD-1ecgA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 7 ARG A 314
ALA A 313
ILE A 315
GLY A 279
 None
 1.01A 3v4tH-1ecgA:
undetectable		 3v4tH-1ecgA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 6 ILE A 407
PHE A 461
TYR A 258
VAL A 365
 None
None
PIN  A 506 ( 4.0A)
None
 1.24A 4a97I-1ecgA:
0.0		 4a97I-1ecgA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJH_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 12 GLU A 209
ASP A 263
GLU A 303
VAL A  22
ASP A 214
 None
None
PIN  A 506 (-4.7A)
None
None
 1.27A 4njhA-1ecgA:
2.2		 4njhA-1ecgA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJK_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 12 GLU A 209
ASP A 263
GLU A 303
VAL A  22
ASP A 214
 None
None
PIN  A 506 (-4.7A)
None
None
 1.25A 4njkA-1ecgA:
2.2		 4njkA-1ecgA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJK_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 12 GLU A 209
ASP A 263
GLU A 303
VAL A  22
ASP A 214
 None
None
PIN  A 506 (-4.7A)
None
None
 1.25A 4njkB-1ecgA:
2.2		 4njkB-1ecgA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0O_A_URFA303_1
(RRNA N-GLYCOSIDASE)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 5 TYR A 167
ASN A 103
TYR A 405
ILE A 187
 None
ONL  A 505 (-4.4A)
None
None
 1.37A 4o0oA-1ecgA:
undetectable		 4o0oA-1ecgA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		3 / 3 ASP A 408
ASN A 103
SER A  81
 None
ONL  A 505 (-4.4A)
None
 0.46A 4obwA-1ecgA:
4.4		 4obwA-1ecgA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 392
GLY A 433
LEU A 293
VAL A 362
ARG A 383
 None
 1.24A 4olmA-1ecgA:
undetectable		 4olmA-1ecgA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_B_SAMB603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 9 LEU A 221
PHE A 220
VAL A 224
ILE A 266
ASP A 267
 None
 1.48A 4pcuA-1ecgA:
0.0
4pcuB-1ecgA:
1.6		 4pcuA-1ecgA:
22.68
4pcuB-1ecgA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 10 ARG A 400
ILE A 425
ALA A 417
LEU A 415
ALA A 412
 None
 1.40A 4xk8B-1ecgA:
undetectable		 4xk8B-1ecgA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSH_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 5 ARG A 482
LEU A 478
ASN A 403
VAL A 404
 None
 1.43A 5cshB-1ecgA:
undetectable		 5cshB-1ecgA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 12 PHE A 461
ALA A 396
ILE A 453
ARG A 275
TYR A 256
 None
 1.18A 5h8tA-1ecgA:
undetectable		 5h8tA-1ecgA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 8 ILE A 174
GLY A  95
PHE A 153
PHE A 239
 None
 0.84A 5hieD-1ecgA:
0.0		 5hieD-1ecgA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_C_IPHC101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 5 CYH A 169
ILE A   3
LEU A  98
HIS A  71
 None
 1.45A 5hrqC-1ecgA:
undetectable
5hrqD-1ecgA:
undetectable
5hrqL-1ecgA:
undetectable		 5hrqC-1ecgA:
3.39
5hrqD-1ecgA:
7.57
5hrqL-1ecgA:
7.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 8 GLN A  24
ALA A 212
SER A 208
HIS A  25
 None
 1.10A 5km8A-1ecgA:
undetectable
5km8B-1ecgA:
undetectable		 5km8A-1ecgA:
14.88
5km8B-1ecgA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 12 GLY A 165
ARG A  26
GLY A   2
ILE A   3
GLY A 186
 None
 0.84A 5koxA-1ecgA:
undetectable		 5koxA-1ecgA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		3 / 3 SER A 368
SER A 394
PHE A 254
 PIN  A 506 ( 3.8A)
None
None
 0.88A 5mugA-1ecgA:
undetectable		 5mugA-1ecgA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 5 ARG A 482
LEU A 478
ASN A 403
VAL A 404
 None
 1.44A 5os7B-1ecgA:
undetectable		 5os7B-1ecgA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		6 / 12 ILE A 407
ARG A 400
ILE A 425
ALA A 417
LEU A 415
ALA A 412
 None
 1.44A 5oy02-1ecgA:
undetectable		 5oy02-1ecgA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		3 / 3 ARG A 275
PHE A 436
LEU A 442
 None
 0.85A 5veuA-1ecgA:
0.0		 5veuA-1ecgA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 10 ILE A 407
ILE A 425
ALA A 417
LEU A 415
ALA A 412
 None
 1.18A 5zjiB-1ecgA:
undetectable		 5zjiB-1ecgA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 8 ASP A 469
ARG A 164
GLU A 457
VAL A 460
 None
 1.27A 6fbvD-1ecgA:
0.0		 6fbvD-1ecgA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 5 ARG A 482
LEU A 478
ASN A 403
VAL A 404
 None
 1.44A 6gmdA-1ecgA:
undetectable		 6gmdA-1ecgA:
21.84