SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1edy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 1edy ALPHA
1-MACROGLOBULIN
(Rattus
norvegicus) 		5 / 10 ILE A  30
VAL A  32
TYR A 115
ILE A  45
ILE A  84
 None
 1.18A 3p4wD-1edyA:
2.5		 3p4wD-1edyA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 1edy ALPHA
1-MACROGLOBULIN
(Rattus
norvegicus) 		5 / 10 ILE A  30
VAL A  32
TYR A 115
ILE A  45
ILE A  84
 None
 1.18A 3p4wE-1edyA:
2.5		 3p4wE-1edyA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 1edy ALPHA
1-MACROGLOBULIN
(Rattus
norvegicus) 		4 / 7 GLY A  36
ILE A  35
VAL A 114
VAL A  44
 None
 0.79A 3ufnB-1edyA:
0.0		 3ufnB-1edyA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1edy ALPHA
1-MACROGLOBULIN
(Rattus
norvegicus) 		4 / 5 TYR A 128
PHE A  17
HIS A  29
PRO A 131
 None
 1.30A 5csyB-1edyA:
undetectable		 5csyB-1edyA:
13.75