SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ee1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 1ee1 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Bacillus
subtilis) 		4 / 4 LEU A  79
ILE A 146
ILE A  75
ALA A  76
 ATP  A5000 (-4.0A)
None
None
None
 0.81A 2i30A-1ee1A:
0.0		 2i30A-1ee1A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 1ee1 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Bacillus
subtilis) 		6 / 12 LEU A  43
GLY A  48
ASP A  89
PRO A  99
ALA A  76
ILE A  45
 ATP  A5000 (-4.7A)
ATP  A5000 (-3.7A)
None
None
None
None
 1.50A 2nmzA-1ee1A:
undetectable		 2nmzA-1ee1A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 1ee1 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Bacillus
subtilis) 		3 / 3 GLU A  67
GLN A  59
ARG A  56
 None
 0.78A 2w3bB-1ee1A:
1.5		 2w3bB-1ee1A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1ee1 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Bacillus
subtilis) 		5 / 12 PRO A 199
ALA A  54
GLY A  55
LEU A  60
ILE A  22
 None
 0.90A 3ku1A-1ee1A:
2.1		 3ku1A-1ee1A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1ee1 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Bacillus
subtilis) 		5 / 12 PRO A 199
ALA A  54
GLY A  55
LEU A  60
ILE A  22
 None
 0.91A 3ku1C-1ee1A:
2.2		 3ku1C-1ee1A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 1ee1 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Bacillus
subtilis) 		5 / 12 GLY A 183
GLN A 188
LEU A 179
GLU A 236
ALA A 160
 None
 1.09A 3sxjA-1ee1A:
2.2		 3sxjA-1ee1A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 1ee1 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Bacillus
subtilis) 		4 / 5 ILE A   6
ILE A 231
TYR A 234
GLU A 230
 None
 1.09A 4a99D-1ee1A:
1.9		 4a99D-1ee1A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1ee1 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Bacillus
subtilis) 		4 / 6 ASP A  50
ASP A 158
ASP A 232
GLU A 162
 ATP  A5000 (-3.5A)
None
None
ATP  A5000 ( 4.4A)
 1.35A 4gkhJ-1ee1A:
0.0		 4gkhJ-1ee1A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1ee1 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Bacillus
subtilis) 		3 / 3 ALA A 198
GLN A  49
THR A  52
 None
 0.75A 5n0oA-1ee1A:
0.0		 5n0oA-1ee1A:
23.14