SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eg1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
4 / 5 LEU A 134
LEU A 137
SER A 106
GLY A 143
None
0.83A 1a4lC-1eg1A:
undetectable
1a4lC-1eg1A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   5
PRO A   8
THR A   7
None
0.76A 1a7yB-1eg1A:
undetectable
1a7yB-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   5
PRO A   8
THR A   7
None
0.67A 1dscC-1eg1A:
undetectable
1dscC-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   7
THR A   5
PRO A   8
None
0.70A 1dscC-1eg1A:
undetectable
1dscC-1eg1A:
4.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
7 / 12 TYR A 146
TYR A 170
ASP A 172
GLN A 174
GLU A 196
ASP A 198
GLU A 201
None
0.39A 1dy4A-1eg1A:
48.7
1dy4A-1eg1A:
43.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
5 / 12 TYR A 146
TYR A 170
ASP A 198
GLU A 201
ASP A 322
None
0.71A 1dy4A-1eg1A:
48.7
1dy4A-1eg1A:
43.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   7
THR A   5
PRO A   8
None
0.75A 1fjaC-1eg1A:
undetectable
1fjaC-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   7
THR A   5
PRO A   8
None
0.74A 1fjaD-1eg1A:
undetectable
1fjaD-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_B_HISB450_0
(HISTIDYL-TRNA
SYNTHETASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
5 / 12 LEU A 112
TYR A 118
GLY A 154
TYR A 110
GLY A 169
None
1.19A 1httB-1eg1A:
undetectable
1httB-1eg1A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   5
PRO A   8
THR A   7
None
0.84A 1i3wE-1eg1A:
undetectable
1i3wE-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   7
THR A   5
PRO A   8
None
0.82A 1i3wE-1eg1A:
undetectable
1i3wE-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   7
THR A   5
PRO A   8
None
0.83A 1i3wF-1eg1A:
undetectable
1i3wF-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   5
PRO A   8
THR A   7
None
0.86A 1i3wG-1eg1A:
undetectable
1i3wG-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   7
THR A   5
PRO A   8
None
0.78A 1i3wG-1eg1A:
undetectable
1i3wG-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   7
THR A   5
PRO A   8
None
0.78A 1i3wH-1eg1A:
undetectable
1i3wH-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   5
PRO A   8
THR A   7
None
0.78A 1mnvD-1eg1A:
undetectable
1mnvD-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   5
PRO A   8
THR A   7
None
0.79A 1ovfB-1eg1A:
undetectable
1ovfB-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   5
PRO A   8
THR A   7
None
0.82A 1unjL-1eg1A:
undetectable
1unjL-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   7
THR A   5
PRO A   8
None
0.79A 1unjL-1eg1A:
undetectable
1unjL-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   5
PRO A   8
THR A   7
None
0.79A 1unjR-1eg1A:
undetectable
1unjR-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   7
THR A   5
PRO A   8
None
0.81A 1unjR-1eg1A:
undetectable
1unjR-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   7
THR A   5
PRO A   8
None
0.76A 1unjW-1eg1A:
undetectable
1unjW-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   5
PRO A   8
THR A   7
None
0.81A 1unjX-1eg1A:
undetectable
1unjX-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   7
THR A   5
PRO A   8
None
0.83A 1unjX-1eg1A:
undetectable
1unjX-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   5
PRO A   8
THR A   7
None
0.81A 1unmE-1eg1A:
undetectable
1unmE-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   7
THR A   5
PRO A   8
None
0.78A 1unmE-1eg1A:
undetectable
1unmE-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   5
PRO A   8
THR A   7
None
0.79A 1unmF-1eg1A:
undetectable
1unmF-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   7
THR A   5
PRO A   8
None
0.81A 1unmF-1eg1A:
undetectable
1unmF-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   7
THR A   5
PRO A   8
None
0.87A 209dC-1eg1A:
undetectable
209dC-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
4 / 8 TYR A  38
ASP A  35
TYR A 170
TYR A 146
None
1.36A 2bteA-1eg1A:
undetectable
2bteA-1eg1A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
4 / 8 TYR A  38
ASP A  35
TYR A 170
TYR A 146
None
1.33A 2bteD-1eg1A:
undetectable
2bteD-1eg1A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
4 / 7 TYR A  38
ASP A  35
TYR A 170
TYR A 146
None
1.30A 2bytA-1eg1A:
undetectable
2bytA-1eg1A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
4 / 7 TYR A  38
ASP A  35
TYR A 170
TYR A 146
None
1.30A 2bytD-1eg1A:
undetectable
2bytD-1eg1A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
4 / 8 TYR A  38
ASP A  35
TYR A 170
TYR A 146
None
1.32A 2v0gA-1eg1A:
undetectable
2v0gA-1eg1A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_D_LEUD1883_0
(AMINOACYL-TRNA
SYNTHETASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
4 / 5 TYR A  38
ASP A  35
TYR A 170
TYR A 146
None
1.37A 2v0gD-1eg1A:
undetectable
2v0gD-1eg1A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   5
PRO A   8
THR A   7
None
0.78A 316dC-1eg1A:
undetectable
316dC-1eg1A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
5 / 11 ILE A 269
LEU A 128
LEU A 209
ILE A 199
LEU A 309
None
1.31A 3a50C-1eg1A:
undetectable
3a50C-1eg1A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
5 / 11 GLY A 169
ALA A 164
GLY A 154
MET A 150
VAL A 314
None
1.24A 4c5lA-1eg1A:
undetectable
4c5lA-1eg1A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
5 / 9 GLY A 169
ALA A 164
GLY A 154
MET A 150
VAL A 314
None
1.24A 4c5lB-1eg1A:
undetectable
4c5lB-1eg1A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
5 / 10 GLY A 169
ALA A 164
GLY A 154
MET A 150
VAL A 314
None
1.25A 4c5lC-1eg1A:
undetectable
4c5lC-1eg1A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
5 / 10 GLY A 169
ALA A 164
GLY A 154
MET A 150
VAL A 314
None
1.24A 4c5lD-1eg1A:
undetectable
4c5lD-1eg1A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
5 / 10 GLY A 169
ALA A 164
GLY A 154
MET A 150
VAL A 314
None
1.26A 4c5nB-1eg1A:
undetectable
4c5nB-1eg1A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
5 / 10 GLY A 169
ALA A 164
GLY A 154
MET A 150
VAL A 314
None
1.34A 4c5nD-1eg1A:
undetectable
4c5nD-1eg1A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 THR A   5
PRO A   8
THR A   7
None
0.85A 4hivD-1eg1A:
undetectable
4hivD-1eg1A:
4.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IPM_A_ACTA503_0
(GH7 FAMILY PROTEIN)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
8 / 9 ASN A 142
TYR A 146
TYR A 170
ASP A 172
GLU A 196
ASP A 198
GLU A 201
TRP A 320
None
0.67A 4ipmA-1eg1A:
48.4
4ipmA-1eg1A:
39.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
4 / 5 GLY A   4
THR A   5
HIS A  42
GLU A  73
None
0.62A 4v20A-1eg1A:
50.4
4v20A-1eg1A:
42.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
5 / 10 VAL A 132
ASP A 133
PHE A 249
SER A 204
SER A 135
None
1.40A 4xp1A-1eg1A:
undetectable
4xp1A-1eg1A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
4 / 5 PHE A 130
LEU A 134
GLY A 202
ILE A 199
None
1.00A 5ik1A-1eg1A:
0.0
5ik1A-1eg1A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
5 / 12 ILE A 319
GLY A 143
LEU A 109
LEU A  89
MET A  91
None
1.01A 5nfjA-1eg1A:
undetectable
5nfjA-1eg1A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
5 / 12 LEU A 309
GLY A 125
LEU A 147
LEU A 315
LEU A 128
None
0.93A 5nfjA-1eg1A:
undetectable
5nfjA-1eg1A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
4 / 6 SER A 148
GLU A 201
ASP A 322
ASP A 172
None
1.23A 5zw4A-1eg1A:
undetectable
5zw4A-1eg1A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
4 / 6 GLY A 230
GLY A 336
PRO A 337
GLY A 333
None
0.71A 6ag0C-1eg1A:
undetectable
6ag0C-1eg1A:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN1_A_LLLA302_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
5 / 10 GLY A 202
TYR A 237
THR A 250
THR A 245
SER A 135
None
1.29A 6mn1A-1eg1A:
0.0
6mn1A-1eg1A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)
1eg1 ENDOGLUCANASE I
(Trichoderma
reesei)
3 / 3 ASP A 172
SER A 144
SER A 318
None
0.81A 6mxtA-1eg1A:
undetectable
6mxtA-1eg1A:
20.45