SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1egx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 1egx VASODILATOR-STIMULAT
ED PHOSPHOPROTEIN
(Homo
sapiens) 		3 / 3 GLU A 114
ALA A 112
SER A 108
 None
 0.68A 1errB-1egxA:
0.0		 1errB-1egxA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA8_0
(GRAMICIDIN A
MINI-GRAMICIDIN A)		 1egx VASODILATOR-STIMULAT
ED PHOSPHOPROTEIN
(Homo
sapiens) 		4 / 4 VAL A  67
TRP A  82
TRP A  89
GLY A  69
 None
 1.38A 1tkqA-1egxA:
undetectable
1tkqB-1egxA:
undetectable		 1tkqA-1egxA:
5.71
1tkqB-1egxA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 1egx VASODILATOR-STIMULAT
ED PHOSPHOPROTEIN
(Homo
sapiens) 		3 / 3 TRP A  82
ALA A  85
VAL A  88
 None
 0.96A 3l8lA-1egxA:
undetectable
3l8lB-1egxA:
undetectable		 3l8lA-1egxA:
9.01
3l8lB-1egxA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 1egx VASODILATOR-STIMULAT
ED PHOSPHOPROTEIN
(Homo
sapiens) 		5 / 12 VAL A  61
GLY A  51
VAL A  36
PHE A  33
PRO A  25
 None
 1.46A 4bvaA-1egxA:
undetectable		 4bvaA-1egxA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 1egx VASODILATOR-STIMULAT
ED PHOSPHOPROTEIN
(Homo
sapiens) 		4 / 5 LEU A 110
ILE A   6
ALA A 112
PHE A  47
 None
 1.04A 4dc3B-1egxA:
undetectable		 4dc3B-1egxA:
15.98