SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ehk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 10 GLY A 399
SER A 400
LEU A 405
PHE A  80
LEU A  25
 None
 1.41A 1a8uA-1ehkA:
undetectable		 1a8uA-1ehkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		4 / 5 LEU A  75
VAL A  79
LEU A  83
GLN A  86
 None
 0.69A 1fbmE-1ehkA:
0.0		 1fbmE-1ehkA:
5.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 TRP A 193
VAL A 158
TRP A 157
 None
 1.40A 1gmkC-1ehkA:
undetectable
1gmkD-1ehkA:
undetectable		 1gmkC-1ehkA:
3.54
1gmkD-1ehkA:
3.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		4 / 6 TRP A 190
VAL A 163
ILE A 162
LEU A  83
 None
 1.32A 1j96A-1ehkA:
undetectable		 1j96A-1ehkA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 THR A  21
LEU A  25
LEU A  32
 None
 0.37A 1mz9C-1ehkA:
undetectable		 1mz9C-1ehkA:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		4 / 4 ALA A 442
VAL A 447
ALA A 379
HIS A 440
 None
 1.03A 1q23F-1ehkA:
0.0		 1q23F-1ehkA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.59A 1rjoA-1ehkA:
undetectable		 1rjoA-1ehkA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.61A 1rkyA-1ehkA:
undetectable		 1rkyA-1ehkA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_A_ADNA1501_1
(CLASS B ACID
PHOSPHATASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 10 PHE A 135
THR A 231
GLY A 232
THR A  70
TYR A 133
 None
None
None
None
HEM  A 800 ( 3.9A)
 1.23A 1rmtA-1ehkA:
0.0		 1rmtA-1ehkA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_A_ADNA1501_1
(CLASS B ACID
PHOSPHATASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 10 PHE A 135
TYR A 146
LEU A 208
THR A 231
GLY A 199
 None
 0.99A 1rmtA-1ehkA:
0.0		 1rmtA-1ehkA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		4 / 8 ALA A 379
LEU A 439
GLY A 438
GLY A  47
 None
 0.87A 1rukH-1ehkA:
undetectable
1rukL-1ehkA:
undetectable		 1rukH-1ehkA:
16.42
1rukL-1ehkA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 ALA A 113
VAL A 153
TRP A 193
 None
 0.89A 1tkqA-1ehkA:
undetectable		 1tkqA-1ehkA:
2.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.17A 1v54A-1ehkA:
35.8		 1v54A-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.22A 1v54N-1ehkA:
35.7		 1v54N-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.20A 1v55A-1ehkA:
35.7		 1v55A-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.22A 1v55N-1ehkA:
35.8		 1v55N-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.66A 1w2zA-1ehkA:
undetectable		 1w2zA-1ehkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.65A 1w2zB-1ehkA:
undetectable		 1w2zB-1ehkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.62A 1w2zC-1ehkA:
undetectable		 1w2zC-1ehkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.63A 1w2zD-1ehkA:
undetectable		 1w2zD-1ehkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 VAL A 163
VAL A 158
TRP A 190
 None
 0.95A 1w5uA-1ehkA:
undetectable
1w5uB-1ehkA:
undetectable		 1w5uA-1ehkA:
3.54
1w5uB-1ehkA:
3.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XMU_A_ROFA101_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 12 LEU A  83
TRP A 239
ILE A  78
SER A 150
PHE A 152
 None
 1.34A 1xmuA-1ehkA:
undetectable		 1xmuA-1ehkA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 12 LEU A  83
TRP A 239
ILE A  78
SER A 150
PHE A 152
 None
 1.33A 1xoqB-1ehkA:
undetectable		 1xoqB-1ehkA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.14A 2dyrA-1ehkA:
35.8		 2dyrA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.22A 2dyrN-1ehkA:
35.8		 2dyrN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.14A 2dysA-1ehkA:
35.9		 2dysA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.13A 2dysN-1ehkA:
35.8		 2dysN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.15A 2eijA-1ehkA:
35.7		 2eijA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.19A 2eijN-1ehkA:
35.8		 2eijN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.10A 2eikA-1ehkA:
35.8		 2eikA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.22A 2eikN-1ehkA:
35.8		 2eikN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.14A 2eilA-1ehkA:
35.8		 2eilA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.20A 2eilN-1ehkA:
35.7		 2eilN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.22A 2eimA-1ehkA:
35.6		 2eimA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.27A 2eimN-1ehkA:
35.6		 2eimN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.03A 2einA-1ehkA:
35.7		 2einA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.26A 2einN-1ehkA:
35.9		 2einN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		4 / 7 THR A 315
ALA A 243
PHE A 269
LEU A 392
 None
 0.95A 2hzqA-1ehkA:
undetectable		 2hzqA-1ehkA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.59A 2oqeA-1ehkA:
undetectable		 2oqeA-1ehkA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.57A 2oqeB-1ehkA:
undetectable		 2oqeB-1ehkA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.58A 2oqeC-1ehkA:
undetectable		 2oqeC-1ehkA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.56A 2oqeD-1ehkA:
undetectable		 2oqeD-1ehkA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.57A 2oqeF-1ehkA:
undetectable		 2oqeF-1ehkA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 12 LEU A 222
LEU A 202
LEU A 546
GLY A 551
LEU A 553
 None
 1.08A 2ouzA-1ehkA:
0.0		 2ouzA-1ehkA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		4 / 4 ALA A 480
VAL A 425
PHE A 484
THR A 394
 None
None
None
HEM  A 800 (-3.6A)
 1.40A 2pkkA-1ehkA:
undetectable		 2pkkA-1ehkA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.62A 2w0qA-1ehkA:
undetectable		 2w0qA-1ehkA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.62A 2w0qB-1ehkA:
undetectable		 2w0qB-1ehkA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.17A 2y69A-1ehkA:
35.9		 2y69A-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.13A 2y69N-1ehkA:
35.8		 2y69N-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.23A 2zxwA-1ehkA:
35.7		 2zxwA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.17A 2zxwN-1ehkA:
35.7		 2zxwN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.26A 3abkA-1ehkA:
35.8		 3abkA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.19A 3abkN-1ehkA:
35.8		 3abkN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.16A 3ablA-1ehkA:
35.7		 3ablA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.20A 3ablN-1ehkA:
35.7		 3ablN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.23A 3abmA-1ehkA:
35.9		 3abmA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.07A 3abmN-1ehkA:
35.7		 3abmN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.26A 3ag1A-1ehkA:
35.4		 3ag1A-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.25A 3ag1N-1ehkA:
35.4		 3ag1N-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.19A 3ag2A-1ehkA:
35.9		 3ag2A-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.23A 3ag2N-1ehkA:
35.7		 3ag2N-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.23A 3ag3A-1ehkA:
35.8		 3ag3A-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.23A 3ag3N-1ehkA:
35.7		 3ag3N-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.41A 3ag4A-1ehkA:
35.8		 3ag4A-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.32A 3ag4N-1ehkA:
35.6		 3ag4N-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.11A 3asnA-1ehkA:
35.9		 3asnA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.16A 3asnN-1ehkA:
35.8		 3asnN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.14A 3asoA-1ehkA:
35.9		 3asoA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.13A 3asoN-1ehkA:
35.8		 3asoN-1ehkA:
28.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.36A 3bvdA-1ehkA:
61.5		 3bvdA-1ehkA:
98.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.22A 3dtuA-1ehkA:
36.8		 3dtuA-1ehkA:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.20A 3dtuC-1ehkA:
36.9		 3dtuC-1ehkA:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.51A 3hiiA-1ehkA:
undetectable		 3hiiA-1ehkA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 282
HIS A 283
HIS A 233
 HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
CU  A 803 (-3.1A)
 0.52A 3hiiB-1ehkA:
undetectable		 3hiiB-1ehkA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 12 GLY A 324
GLY A 329
ALA A 255
PHE A 333
LEU A 339
 None
 1.06A 3mteB-1ehkA:
undetectable		 3mteB-1ehkA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		4 / 8 LEU A 251
ALA A 318
GLY A 352
PRO A 349
 None
 0.78A 3ny4A-1ehkA:
1.4		 3ny4A-1ehkA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 9 ALA A 534
ILE A 536
GLY A 528
ILE A 527
LEU A 274
 None
 0.91A 3ogpA-1ehkA:
undetectable		 3ogpA-1ehkA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 10 ALA A 534
ILE A 536
GLY A 528
ILE A 527
LEU A 274
 None
 0.91A 3ogpA-1ehkA:
undetectable		 3ogpA-1ehkA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 9 ALA A 534
ILE A 536
GLY A 528
ILE A 527
LEU A 274
 None
 1.02A 3ogpB-1ehkA:
undetectable		 3ogpB-1ehkA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 10 ALA A 534
ILE A 536
GLY A 528
ILE A 527
LEU A 274
 None
 0.96A 3ogqA-1ehkA:
undetectable		 3ogqA-1ehkA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 12 ALA A 534
ILE A 536
GLY A 528
ILE A 527
LEU A 274
 None
 0.98A 3ogqB-1ehkA:
undetectable		 3ogqB-1ehkA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 10 LEU A 273
ALA A 532
PHE A 531
GLY A 528
ILE A 527
 None
 1.21A 3qpsA-1ehkA:
0.0		 3qpsA-1ehkA:
16.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.28A 3s33A-1ehkA:
62.4		 3s33A-1ehkA:
98.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.37A 3s38A-1ehkA:
60.9		 3s38A-1ehkA:
98.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.26A 3s39A-1ehkA:
62.5		 3s39A-1ehkA:
98.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.32A 3s3aA-1ehkA:
59.8		 3s3aA-1ehkA:
98.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.26A 3s3bA-1ehkA:
63.1		 3s3bA-1ehkA:
98.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.35A 3s3cA-1ehkA:
62.3		 3s3cA-1ehkA:
98.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.29A 3s3dA-1ehkA:
62.5		 3s3dA-1ehkA:
98.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 12 ALA A 367
LEU A 371
GLY A 362
HIS A 384
LEU A 310
 HAS  A 801 (-3.4A)
None
None
HAS  A 801 (-4.4A)
HAS  A 801 (-4.0A)
 1.23A 3tm4A-1ehkA:
undetectable		 3tm4A-1ehkA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 12 ALA A 367
LEU A 371
GLY A 362
HIS A 384
LEU A 310
 HAS  A 801 (-3.4A)
None
None
HAS  A 801 (-4.4A)
HAS  A 801 (-4.0A)
 1.22A 3tm4B-1ehkA:
undetectable		 3tm4B-1ehkA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.06A 3wg7A-1ehkA:
35.6		 3wg7A-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.17A 3wg7N-1ehkA:
35.6		 3wg7N-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.21A 3x2qA-1ehkA:
35.8		 3x2qA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.06A 3x2qN-1ehkA:
35.8		 3x2qN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 12 PHE A 385
PRO A 382
LEU A 439
TYR A  46
GLN A  42
 HAS  A 801 ( 3.7A)
None
None
HEM  A 800 (-4.5A)
HEM  A 800 (-4.4A)
 1.47A 4a84A-1ehkA:
undetectable		 4a84A-1ehkA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		4 / 5 VAL A 163
ILE A 250
MET A 185
ILE A 246
 None
 0.82A 4c8bA-1ehkA:
undetectable		 4c8bA-1ehkA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 ASN A  76
LEU A 117
PHE A  29
 HEM  A 800 (-4.2A)
None
None
 0.60A 4dajB-1ehkA:
0.0		 4dajB-1ehkA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		4 / 8 PHE A 429
GLY A 355
LEU A 354
ILE A 357
 None
 0.87A 4em2A-1ehkA:
0.0		 4em2A-1ehkA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.12A 5b1aA-1ehkA:
35.8		 5b1aA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.21A 5b1aN-1ehkA:
35.9		 5b1aN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.20A 5b1bA-1ehkA:
35.8		 5b1bA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.24A 5b1bN-1ehkA:
35.7		 5b1bN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.18A 5b3sA-1ehkA:
35.9		 5b3sA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.24A 5b3sN-1ehkA:
35.8		 5b3sN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 ASN A  76
LEU A 117
PHE A  29
 HEM  A 800 (-4.2A)
None
None
 0.45A 5dsgA-1ehkA:
4.2		 5dsgA-1ehkA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		4 / 5 ALA A 541
PRO A 234
GLY A  73
LEU A 200
 None
None
HEM  A 800 ( 4.2A)
None
 1.00A 5eslA-1ehkA:
1.3		 5eslA-1ehkA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 12 LEU A 125
GLN A  67
VAL A  62
PHE A  61
GLY A  35
 None
 1.30A 5i8fA-1ehkA:
undetectable		 5i8fA-1ehkA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.18A 5iy5A-1ehkA:
35.8		 5iy5A-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.19A 5iy5N-1ehkA:
35.7		 5iy5N-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 LEU A 191
LEU A 195
TRP A 230
 None
 0.94A 5nwuA-1ehkA:
0.0		 5nwuA-1ehkA:
5.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 10 PHE A 152
ALA A 121
LEU A 117
GLY A 116
LEU A 401
 None
 1.19A 5oy01-1ehkA:
0.6
5oy07-1ehkA:
0.0		 5oy01-1ehkA:
8.78
5oy07-1ehkA:
5.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.23A 5w97a-1ehkA:
35.5		 5w97a-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.22A 5waua-1ehkA:
35.9		 5waua-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.25A 5x19A-1ehkA:
35.5		 5x19A-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.26A 5x19N-1ehkA:
35.4		 5x19N-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.25A 5x1bA-1ehkA:
35.1		 5x1bA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.20A 5x1bN-1ehkA:
34.9		 5x1bN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.28A 5x1fA-1ehkA:
35.4		 5x1fA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.19A 5x1fN-1ehkA:
35.5		 5x1fN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.13A 5xdqA-1ehkA:
36.0		 5xdqA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.16A 5xdqN-1ehkA:
35.8		 5xdqN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.15A 5xdxA-1ehkA:
36.0		 5xdxA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.14A 5xdxN-1ehkA:
35.8		 5xdxN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		4 / 4 PHE A  38
LEU A 117
LEU A 125
VAL A  74
 None
 1.30A 5xxiA-1ehkA:
0.0		 5xxiA-1ehkA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.18A 5z84A-1ehkA:
35.9		 5z84A-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.18A 5z84N-1ehkA:
35.8		 5z84N-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.20A 5z85A-1ehkA:
35.9		 5z85A-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.17A 5z85N-1ehkA:
35.8		 5z85N-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.00A 5z86A-1ehkA:
36.0		 5z86A-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.16A 5z86N-1ehkA:
35.8		 5z86N-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.17A 5zcoA-1ehkA:
35.8		 5zcoA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.07A 5zcoN-1ehkA:
35.7		 5zcoN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.12A 5zcpA-1ehkA:
35.8		 5zcpA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.19A 5zcpN-1ehkA:
35.8		 5zcpN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.08A 5zcqA-1ehkA:
35.9		 5zcqA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.10A 5zcqN-1ehkA:
35.9		 5zcqN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		5 / 11 VAL A  79
VAL A  26
LEU A  27
ALA A 120
VAL A  34
 None
 1.32A 6dryA-1ehkA:
5.4		 6dryA-1ehkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.68A 6giqa-1ehkA:
33.0		 6giqa-1ehkA:
27.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.12A 6hu9a-1ehkA:
34.8		 6hu9a-1ehkA:
27.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.21A 6hu9m-1ehkA:
34.8		 6hu9m-1ehkA:
27.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.17A 6nknA-1ehkA:
35.2		 6nknA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.15A 6nknN-1ehkA:
35.2		 6nknN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.24A 6nmfA-1ehkA:
35.3		 6nmfA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.25A 6nmfN-1ehkA:
35.0		 6nmfN-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.20A 6nmpA-1ehkA:
35.4		 6nmpA-1ehkA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ehk BA3-TYPE
CYTOCHROME-C OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 233
HIS A 282
HIS A 283
 CU  A 803 (-3.1A)
HAS  A 801 ( 3.3A)
CU  A 803 ( 3.2A)
 0.21A 6nmpN-1ehkA:
35.3		 6nmpN-1ehkA:
28.26