SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ehl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 1ehl ANTI-(6-4)
PHOTOPRODUCT
ANTIBODY 64M-2 FAB
(HEAVY CHAIN)
(Mus
musculus) 		3 / 3 PRO H  14
SER H 113
ASN H  84
 None
 0.90A 3lslG-1ehlH:
undetectable		 3lslG-1ehlH:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 1ehl ANTI-(6-4)
PHOTOPRODUCT
ANTIBODY 64M-2 FAB
(HEAVY CHAIN)
(Mus
musculus) 		5 / 12 VAL H 171
VAL H 191
SER H 189
ASN H 209
ASN H 162
 None
 1.41A 3nyaA-1ehlH:
undetectable		 3nyaA-1ehlH:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1ehl ANTI-(6-4)
PHOTOPRODUCT
ANTIBODY 64M-2 FAB
(HEAVY CHAIN)
(Mus
musculus) 		3 / 3 GLN H   3
GLU H   1
LYS H   1
 None
 1.13A 3su9A-1ehlH:
0.0		 3su9A-1ehlH:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 1ehl ANTI-(6-4)
PHOTOPRODUCT
ANTIBODY 64M-2 FAB
(HEAVY CHAIN)
(Mus
musculus) 		3 / 3 TYR H  90
GLN H  43
TRP H  47
 None
 1.02A 4kn2C-1ehlH:
0.0		 4kn2C-1ehlH:
20.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 1ehl ANTI-(6-4)
PHOTOPRODUCT
ANTIBODY 64M-2 FAB
(HEAVY CHAIN)
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  94
TYR H 102
 None
 0.40A 4m7kH-1ehlH:
23.6		 4m7kH-1ehlH:
65.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 1ehl ANTI-(6-4)
PHOTOPRODUCT
ANTIBODY 64M-2 FAB
(HEAVY CHAIN)
(Mus
musculus) 		5 / 11 PRO H  14
VAL H 111
ALA H  12
SER H  82
SER H  17
 None
 1.22A 4mmaA-1ehlH:
undetectable		 4mmaA-1ehlH:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1ehl ANTI-(6-4)
PHOTOPRODUCT
ANTIBODY 64M-2 FAB
(HEAVY CHAIN)
(Mus
musculus) 		5 / 11 THR H  57
THR H  50
GLY H  53
ALA H  71
THR H  73
 None
 1.50A 4qvmV-1ehlH:
undetectable
4qvmb-1ehlH:
undetectable		 4qvmV-1ehlH:
22.27
4qvmb-1ehlH:
18.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UIN_H_QI9H1226_0
(FAB 314.3)		 1ehl ANTI-(6-4)
PHOTOPRODUCT
ANTIBODY 64M-2 FAB
(HEAVY CHAIN)
(Mus
musculus) 		5 / 12 TRP H  33
HIS H  35
TRP H  47
THR H  50
SER H  58
 None
 0.35A 4uinH-1ehlH:
27.3
4uinL-1ehlH:
17.6		 4uinH-1ehlH:
83.26
4uinL-1ehlH:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1ehl ANTI-(6-4)
PHOTOPRODUCT
ANTIBODY 64M-2 FAB
(HEAVY CHAIN)
(Mus
musculus) 		4 / 5 GLY H  42
ARG H  40
GLY H  44
GLU H  46
 None
 1.24A 4z2eB-1ehlH:
undetectable
4z2eC-1ehlH:
undetectable		 4z2eB-1ehlH:
15.73
4z2eC-1ehlH:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1ehl ANTI-(6-4)
PHOTOPRODUCT
ANTIBODY 64M-2 FAB
(HEAVY CHAIN)
(Mus
musculus) 		5 / 8 VAL H 121
ALA H 118
THR H 217
VAL H 152
VAL H 210
 None
 1.46A 5l94A-1ehlH:
0.0		 5l94A-1ehlH:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ehl ANTI-(6-4)
PHOTOPRODUCT
ANTIBODY 64M-2 FAB
(HEAVY CHAIN)
(Mus
musculus) 		4 / 6 LYS H 145
LEU H 187
PHE H 174
LEU H 154
 None
 1.06A 5w97C-1ehlH:
undetectable
5w97J-1ehlH:
undetectable		 5w97C-1ehlH:
21.45
5w97J-1ehlH:
15.74