SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ehx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 1ehx SCAFFOLDIN PROTEIN
([Clostridium]
cellulolyticum) 		4 / 8 THR A  24
ASN A   7
LEU A  68
GLU A  37
 None
 1.20A 1mxgA-1ehxA:
undetectable		 1mxgA-1ehxA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ehx SCAFFOLDIN PROTEIN
([Clostridium]
cellulolyticum) 		4 / 8 GLN A   2
PHE A  72
ASN A  28
ASP A   3
 None
 1.34A 1p6kA-1ehxA:
undetectable		 1p6kA-1ehxA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ehx SCAFFOLDIN PROTEIN
([Clostridium]
cellulolyticum) 		4 / 8 ASN A  78
GLN A   2
PHE A  72
ASN A  33
 None
 1.14A 1rs7B-1ehxA:
undetectable		 1rs7B-1ehxA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ehx SCAFFOLDIN PROTEIN
([Clostridium]
cellulolyticum) 		4 / 8 GLN A   2
PHE A  72
ASN A  28
ASP A   3
 None
 1.31A 1zzqA-1ehxA:
undetectable		 1zzqA-1ehxA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 1ehx SCAFFOLDIN PROTEIN
([Clostridium]
cellulolyticum) 		4 / 8 ASN A  78
GLN A   2
PHE A  72
ASN A  33
 None
 1.17A 3n62A-1ehxA:
undetectable		 3n62A-1ehxA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1ehx SCAFFOLDIN PROTEIN
([Clostridium]
cellulolyticum) 		4 / 8 ASN A  78
GLN A   2
PHE A  72
ASN A  33
 None
 1.11A 3n62B-1ehxA:
undetectable		 3n62B-1ehxA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1ehx SCAFFOLDIN PROTEIN
([Clostridium]
cellulolyticum) 		4 / 8 ASN A  78
GLN A   2
PHE A  72
ASN A  33
 None
 1.11A 3n66B-1ehxA:
undetectable		 3n66B-1ehxA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1ehx SCAFFOLDIN PROTEIN
([Clostridium]
cellulolyticum) 		5 / 9 GLU A  37
LEU A  68
THR A  84
VAL A  85
LEU A  60
 None
 1.41A 3uncA-1ehxA:
undetectable		 3uncA-1ehxA:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1ehx SCAFFOLDIN PROTEIN
([Clostridium]
cellulolyticum) 		5 / 9 GLU A  37
LEU A  68
THR A  84
VAL A  85
LEU A  60
 None
 1.42A 3uncB-1ehxA:
undetectable		 3uncB-1ehxA:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ehx SCAFFOLDIN PROTEIN
([Clostridium]
cellulolyticum) 		4 / 7 ASN A  78
GLN A   2
PHE A  72
ASN A  33
 None
 1.11A 4kcnB-1ehxA:
undetectable		 4kcnB-1ehxA:
15.90