SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ei5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		4 / 8 LEU A 110
ARG A 159
PHE A 158
GLY A 224
 None
 0.97A 1fapB-1ei5A:
0.0		 1fapB-1ei5A:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		4 / 6 ALA A 371
SER A 338
ARG A 397
LEU A 359
 None
 1.12A 1gahA-1ei5A:
undetectable		 1gahA-1ei5A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		3 / 3 THR A  68
LEU A  72
VAL A  76
 None
 0.52A 1mz9E-1ei5A:
undetectable		 1mz9E-1ei5A:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		4 / 6 SER A 152
SER A 108
LEU A 110
GLY A 109
 None
 0.95A 2j2pA-1ei5A:
0.0
2j2pC-1ei5A:
0.0		 2j2pA-1ei5A:
17.11
2j2pC-1ei5A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		4 / 6 SER A 152
SER A 108
LEU A 110
GLY A 109
 None
 0.94A 2j2pD-1ei5A:
0.0
2j2pF-1ei5A:
undetectable		 2j2pD-1ei5A:
17.11
2j2pF-1ei5A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		5 / 12 LEU A 490
LEU A 474
GLN A 477
LEU A 119
CYH A 507
 None
 1.39A 2w8yB-1ei5A:
undetectable		 2w8yB-1ei5A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		4 / 6 THR A 393
ARG A 511
PHE A 373
LEU A 359
 None
 0.98A 2wm3A-1ei5A:
undetectable		 2wm3A-1ei5A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		5 / 12 LEU A 490
LEU A 474
GLN A 477
LEU A 119
CYH A 507
 None
 1.38A 3d90A-1ei5A:
undetectable		 3d90A-1ei5A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		5 / 8 GLY A 454
ALA A 437
ASP A 436
LEU A 440
VAL A 505
 None
 1.40A 3em6A-1ei5A:
undetectable		 3em6A-1ei5A:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		5 / 11 GLY A 317
ALA A 318
VAL A  26
GLY A  25
PRO A  59
 None
 0.90A 3ufnA-1ei5A:
undetectable		 3ufnA-1ei5A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		4 / 8 ASN A 233
ILE A 309
SER A 231
ALA A  40
 None
 1.02A 4eyzA-1ei5A:
0.0		 4eyzA-1ei5A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		4 / 8 TYR A  20
ILE A  16
GLY A  24
PHE A 312
 None
 0.89A 4iqqD-1ei5A:
undetectable		 4iqqD-1ei5A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		5 / 12 GLY A 506
GLY A 512
LEU A 503
THR A 375
ALA A 115
 None
 0.75A 5kpcA-1ei5A:
undetectable		 5kpcA-1ei5A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_0
(REGULATORY PROTEIN
TETR)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		5 / 12 ALA A  99
GLU A 146
ARG A 111
CYH A 154
PHE A 145
 None
 1.27A 5vlmC-1ei5A:
0.0		 5vlmC-1ei5A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		5 / 12 TYR A 113
PHE A 145
ALA A 162
THR A  68
LEU A 103
 None
 1.12A 6aybA-1ei5A:
undetectable		 6aybA-1ei5A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_B_ACTB207_0
(DUF1778
DOMAIN-CONTAINING
PROTEIN
N-ACETYLTRANSFERASE)		 1ei5 D-AMINOPEPTIDASE
(Ochrobactrum
anthropi) 		4 / 6 LEU A 509
THR A 375
CYH A 507
GLY A 486
 None
 0.98A 6gtqB-1ei5A:
undetectable
6gtqD-1ei5A:
undetectable		 6gtqB-1ei5A:
18.30
6gtqD-1ei5A:
6.73