SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eiz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EIZ_A_SAMA301_0
(FTSJ)		 1eiz FTSJ
(Escherichia
coli) 		12 / 12 ALA A  35
GLY A  59
PRO A  62
GLY A  63
GLY A  64
TRP A  65
LEU A  84
LEU A  85
PHE A 100
ARG A 101
LEU A 143
LYS A 164
 SAM  A 301 (-3.3A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.2A)
SAM  A 301 ( 4.2A)
None
SAM  A 301 (-4.7A)
SAM  A 301 (-4.6A)
SAM  A 301 ( 3.9A)
 0.00A 1eizA-1eizA:
38.6		 1eizA-1eizA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EIZ_A_SAMA301_1
(FTSJ)		 1eiz FTSJ
(Escherichia
coli) 		3 / 3 ASP A  83
ASP A  99
ASP A 124
 SAM  A 301 (-2.8A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.01A 1eizA-1eizA:
38.6		 1eizA-1eizA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EJ0_A_SAMA301_0
(FTSJ)		 1eiz FTSJ
(Escherichia
coli) 		12 / 12 ALA A  35
GLY A  59
PRO A  62
GLY A  63
GLY A  64
TRP A  65
LEU A  84
LEU A  85
PHE A 100
ARG A 101
LEU A 143
LYS A 164
 SAM  A 301 (-3.3A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.2A)
SAM  A 301 ( 4.2A)
None
SAM  A 301 (-4.7A)
SAM  A 301 (-4.6A)
SAM  A 301 ( 3.9A)
 0.14A 1ej0A-1eizA:
36.9		 1ej0A-1eizA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EJ0_A_SAMA301_0
(FTSJ)		 1eiz FTSJ
(Escherichia
coli) 		6 / 12 GLY A  59
GLY A  63
PHE A 100
ARG A 101
LEU A 143
LYS A 164
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.9A)
None
SAM  A 301 (-4.7A)
SAM  A 301 (-4.6A)
SAM  A 301 ( 3.9A)
 0.93A 1ej0A-1eizA:
36.9		 1ej0A-1eizA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EJ0_A_SAMA301_1
(FTSJ)		 1eiz FTSJ
(Escherichia
coli) 		3 / 3 ASP A  83
ASP A  99
ASP A 124
 SAM  A 301 (-2.8A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.08A 1ej0A-1eizA:
36.9		 1ej0A-1eizA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 1eiz FTSJ
(Escherichia
coli) 		4 / 8 SER A  66
ALA A  81
PHE A  95
ILE A  80
 None
 1.16A 1gm7A-1eizA:
undetectable
1gm7B-1eizA:
undetectable		 1gm7A-1eizA:
21.80
1gm7B-1eizA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 1eiz FTSJ
(Escherichia
coli) 		3 / 3 PRO A  62
ASP A  83
ASP A 124
 SAM  A 301 (-3.4A)
SAM  A 301 (-2.8A)
SAM  A 301 (-3.6A)
 0.34A 1sqfA-1eizA:
11.7		 1sqfA-1eizA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 PRO A  62
GLY A  63
LEU A  84
ASP A  99
PHE A 100
 SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.5A)
None
 0.81A 2b9eA-1eizA:
13.1		 2b9eA-1eizA:
20.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1eiz FTSJ
(Escherichia
coli) 		9 / 12 GLY A  59
ALA A  61
GLY A  63
TRP A  65
LEU A  84
LEU A  85
MET A 125
LEU A 143
LYS A 164
 SAM  A 301 (-3.6A)
SAM  A 301 (-4.0A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.2A)
SAM  A 301 ( 4.2A)
SAM  A 301 (-4.3A)
SAM  A 301 (-4.6A)
SAM  A 301 ( 3.9A)
 0.49A 2nyuA-1eizA:
26.6		 2nyuA-1eizA:
36.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
MET A 125
LEU A 143
LYS A 164
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-4.3A)
SAM  A 301 (-4.6A)
SAM  A 301 ( 3.9A)
 0.96A 2nyuA-1eizA:
26.6		 2nyuA-1eizA:
36.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NYU_A_SAMA201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1eiz FTSJ
(Escherichia
coli) 		4 / 4 PRO A  62
ASP A  83
ASP A  99
ASP A  57
 SAM  A 301 (-3.4A)
SAM  A 301 (-2.8A)
SAM  A 301 (-3.5A)
None
 1.14A 2nyuA-1eizA:
26.6		 2nyuA-1eizA:
36.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NYU_A_SAMA201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1eiz FTSJ
(Escherichia
coli) 		4 / 4 PRO A  62
ASP A  83
ASP A  99
ASP A 124
 SAM  A 301 (-3.4A)
SAM  A 301 (-2.8A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.45A 2nyuA-1eizA:
26.6		 2nyuA-1eizA:
36.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1eiz FTSJ
(Escherichia
coli) 		9 / 12 GLY A  59
ALA A  61
GLY A  63
TRP A  65
LEU A  84
LEU A  85
MET A 125
LEU A 143
LYS A 164
 SAM  A 301 (-3.6A)
SAM  A 301 (-4.0A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.2A)
SAM  A 301 ( 4.2A)
SAM  A 301 (-4.3A)
SAM  A 301 (-4.6A)
SAM  A 301 ( 3.9A)
 0.48A 2nyuB-1eizA:
26.5		 2nyuB-1eizA:
36.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
MET A 125
LEU A 143
LYS A 164
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-4.3A)
SAM  A 301 (-4.6A)
SAM  A 301 ( 3.9A)
 0.98A 2nyuB-1eizA:
26.5		 2nyuB-1eizA:
36.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1eiz FTSJ
(Escherichia
coli) 		4 / 5 PRO A  62
ASP A  83
ASP A  99
ASP A  57
 SAM  A 301 (-3.4A)
SAM  A 301 (-2.8A)
SAM  A 301 (-3.5A)
None
 1.19A 2nyuB-1eizA:
26.5		 2nyuB-1eizA:
36.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1eiz FTSJ
(Escherichia
coli) 		4 / 5 PRO A  62
ASP A  83
ASP A  99
ASP A 124
 SAM  A 301 (-3.4A)
SAM  A 301 (-2.8A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.44A 2nyuB-1eizA:
26.5		 2nyuB-1eizA:
36.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
LEU A  84
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.6A)
 0.45A 2oxtA-1eizA:
15.2		 2oxtA-1eizA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  63
TRP A  65
LEU A  84
LYS A 164
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.2A)
SAM  A 301 ( 3.9A)
 0.47A 2oxtB-1eizA:
15.3		 2oxtB-1eizA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		4 / 5 SER A  33
GLY A  64
ASP A  99
ASP A 124
 SAM  A 301 ( 4.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.78A 2oxtB-1eizA:
15.3		 2oxtB-1eizA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		6 / 12 GLY A  59
GLY A  64
TRP A  65
LEU A  84
ASP A 124
LYS A 164
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.6A)
SAM  A 301 ( 3.9A)
 0.49A 2oxtC-1eizA:
15.3		 2oxtC-1eizA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 ASP A  57
GLY A  59
GLY A  64
LEU A  84
ASP A 124
 None
SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.6A)
 0.59A 2oxtD-1eizA:
15.2		 2oxtD-1eizA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1eiz FTSJ
(Escherichia
coli) 		6 / 12 ALA A  35
GLY A  59
PRO A  62
GLY A  63
TRP A  65
LEU A 143
 SAM  A 301 (-3.3A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.6A)
 0.61A 2plwA-1eizA:
24.7		 2plwA-1eizA:
28.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.45A 2pxcA-1eizA:
15.0		 2pxcA-1eizA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1eiz FTSJ
(Escherichia
coli) 		4 / 8 ILE A  79
GLY A  64
GLY A  63
MET A  87
 None
SAM  A 301 (-3.1A)
SAM  A 301 (-3.9A)
None
 0.79A 2qx4A-1eizA:
2.3
2qx4B-1eizA:
2.7		 2qx4A-1eizA:
23.35
2qx4B-1eizA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 SER A  33
GLY A  59
TRP A  65
LEU A  84
ASP A 124
 SAM  A 301 ( 4.6A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.6A)
 0.81A 2wa2B-1eizA:
15.5		 2wa2B-1eizA:
23.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1eiz FTSJ
(Escherichia
coli) 		8 / 12 ALA A  35
GLY A  59
PRO A  62
GLY A  63
GLY A  64
TRP A  65
LEU A  84
LYS A 164
 SAM  A 301 (-3.3A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.2A)
SAM  A 301 ( 3.9A)
 0.33A 3douA-1eizA:
26.9		 3douA-1eizA:
33.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1eiz FTSJ
(Escherichia
coli) 		3 / 3 ASP A  83
ASP A  99
ASP A 124
 SAM  A 301 (-2.8A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.15A 3douA-1eizA:
26.9		 3douA-1eizA:
33.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
LEU A  84
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.6A)
 0.27A 3eluA-1eizA:
14.8		 3eluA-1eizA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
LEU A  84
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.6A)
 0.29A 3elwA-1eizA:
15.1		 3elwA-1eizA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
LEU A  84
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.6A)
 0.24A 3embA-1eizA:
15.2		 3embA-1eizA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 1eiz FTSJ
(Escherichia
coli) 		6 / 12 GLY A  59
GLY A  64
TRP A  65
LEU A  84
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.58A 3gczA-1eizA:
15.6		 3gczA-1eizA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 1eiz FTSJ
(Escherichia
coli) 		4 / 8 SER A 160
ASP A  46
VAL A 187
LEU A 175
 None
 1.07A 3jq7C-1eizA:
8.8		 3jq7C-1eizA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		3 / 3 SER A 130
GLY A 131
THR A 132
 None
 0.24A 3k9wA-1eizA:
undetectable		 3k9wA-1eizA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 PRO A  62
GLY A  63
GLY A  64
ASP A  57
LEU A 109
 SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.1A)
None
None
 1.10A 3m6vA-1eizA:
10.8		 3m6vA-1eizA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 PRO A  62
GLY A  63
GLY A  64
ASP A 124
LEU A 143
 SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.6A)
 0.33A 3m6vA-1eizA:
10.8		 3m6vA-1eizA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 PRO A  62
GLY A  63
GLY A  64
ASP A  57
LEU A 109
 SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.1A)
None
None
 1.06A 3m6vB-1eizA:
10.0		 3m6vB-1eizA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 PRO A  62
GLY A  63
GLY A  64
ASP A 124
LEU A 143
 SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.6A)
 0.33A 3m6vB-1eizA:
10.0		 3m6vB-1eizA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.44A 3p97A-1eizA:
14.7		 3p97A-1eizA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.40A 3p97C-1eizA:
14.5		 3p97C-1eizA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
LEU A  84
ASP A  99
MET A 125
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.5A)
SAM  A 301 (-4.3A)
 0.98A 3r24A-1eizA:
14.9		 3r24A-1eizA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
LEU A  84
ASP A  99
MET A 125
LYS A 164
 SAM  A 301 (-3.6A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.5A)
SAM  A 301 (-4.3A)
SAM  A 301 ( 3.9A)
 0.81A 3r24A-1eizA:
14.9		 3r24A-1eizA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 1eiz FTSJ
(Escherichia
coli) 		8 / 12 GLY A  59
PRO A  62
GLY A  63
GLY A  64
TRP A  65
ASP A  83
ASP A 124
MET A 125
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-2.8A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.3A)
 0.50A 4b17A-1eizA:
15.3		 4b17A-1eizA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 1eiz FTSJ
(Escherichia
coli) 		7 / 12 PRO A  62
GLY A  63
GLY A  64
TRP A  65
ASP A  83
ASP A  99
ASP A 124
 SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-2.8A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.79A 4b17A-1eizA:
15.3		 4b17A-1eizA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 1eiz FTSJ
(Escherichia
coli) 		6 / 12 SER A  33
GLY A  59
GLY A  64
TRP A  65
ASP A 124
MET A 125
 SAM  A 301 ( 4.6A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.3A)
 1.01A 4b17A-1eizA:
15.3		 4b17A-1eizA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.39A 4ctjA-1eizA:
14.7		 4ctjA-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.42A 4ctkA-1eizA:
14.7		 4ctkA-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 SER A  33
GLY A  59
GLY A  64
TRP A  65
ASP A 124
 SAM  A 301 ( 4.6A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.6A)
 0.71A 4ctkC-1eizA:
14.5		 4ctkC-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1eiz FTSJ
(Escherichia
coli) 		4 / 8 THR A 205
LEU A  48
ARG A 188
VAL A 162
 None
 0.88A 4em2A-1eizA:
0.0		 4em2A-1eizA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1eiz FTSJ
(Escherichia
coli) 		4 / 7 MET A 150
ILE A  80
ARG A  78
ARG A 112
 None
 1.34A 4f4dA-1eizA:
2.2		 4f4dA-1eizA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1eiz FTSJ
(Escherichia
coli) 		4 / 8 MET A 150
ILE A  80
ARG A  78
ARG A 112
 None
 1.28A 4f4dB-1eizA:
3.2		 4f4dB-1eizA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 1eiz FTSJ
(Escherichia
coli) 		6 / 12 PRO A  62
GLY A  63
GLY A  64
LEU A  84
ASP A 124
LEU A 143
 SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.1A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.6A)
 0.71A 4fp9A-1eizA:
9.5		 4fp9A-1eizA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 1eiz FTSJ
(Escherichia
coli) 		6 / 12 PRO A  62
GLY A  63
GLY A  64
LEU A  84
ASP A 124
LEU A 143
 SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.1A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.6A)
 0.71A 4fp9C-1eizA:
9.6		 4fp9C-1eizA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 1eiz FTSJ
(Escherichia
coli) 		6 / 12 PRO A  62
GLY A  63
GLY A  64
LEU A  84
ASP A  99
LEU A 143
 SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.1A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.5A)
SAM  A 301 (-4.6A)
 0.88A 4fp9D-1eizA:
9.5		 4fp9D-1eizA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 1eiz FTSJ
(Escherichia
coli) 		6 / 12 PRO A  62
GLY A  63
GLY A  64
LEU A  84
ASP A 124
LEU A 143
 SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.1A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.6A)
 0.71A 4fp9F-1eizA:
9.5		 4fp9F-1eizA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 1eiz FTSJ
(Escherichia
coli) 		6 / 12 PRO A  62
GLY A  63
GLY A  64
LEU A  84
ASP A  99
LEU A 143
 SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-3.1A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.5A)
SAM  A 301 (-4.6A)
 0.86A 4fzvA-1eizA:
9.4		 4fzvA-1eizA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 ALA A  35
GLY A  59
ASP A  83
LEU A  84
LEU A  85
 SAM  A 301 (-3.3A)
SAM  A 301 (-3.6A)
SAM  A 301 (-2.8A)
SAM  A 301 (-4.2A)
SAM  A 301 ( 4.2A)
 0.65A 4lg1A-1eizA:
10.5		 4lg1A-1eizA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 ALA A  35
GLY A  59
ASP A  83
LEU A  84
LEU A  85
 SAM  A 301 (-3.3A)
SAM  A 301 (-3.6A)
SAM  A 301 (-2.8A)
SAM  A 301 (-4.2A)
SAM  A 301 ( 4.2A)
 0.63A 4lg1C-1eizA:
9.6		 4lg1C-1eizA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1eiz FTSJ
(Escherichia
coli) 		4 / 5 ALA A  35
GLY A  64
ASP A  99
ASP A 124
 SAM  A 301 (-3.3A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.30A 4n48A-1eizA:
18.3		 4n48A-1eizA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1eiz FTSJ
(Escherichia
coli) 		4 / 5 PRO A  62
GLY A  64
ASP A  99
ASP A 124
 SAM  A 301 (-3.4A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.34A 4n48B-1eizA:
18.3		 4n48B-1eizA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 ALA A  35
PRO A  62
GLY A  63
LEU A  84
LEU A 143
 SAM  A 301 (-3.3A)
SAM  A 301 (-3.4A)
SAM  A 301 (-3.9A)
SAM  A 301 (-4.2A)
SAM  A 301 (-4.6A)
 0.61A 4n49A-1eizA:
17.8		 4n49A-1eizA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_C_SAMC401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 11 SER A  33
GLY A  59
ASP A  83
LEU A  84
ASP A  99
 SAM  A 301 ( 4.6A)
SAM  A 301 (-3.6A)
SAM  A 301 (-2.8A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.5A)
 1.20A 4pghC-1eizA:
11.8		 4pghC-1eizA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 10 ASP A  57
GLY A  59
ALA A  60
ILE A  90
VAL A  69
 None
SAM  A 301 (-3.6A)
None
None
None
 0.95A 4q1yA-1eizA:
undetectable		 4q1yA-1eizA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 PHE A  95
GLY A  59
ALA A  60
ILE A  79
ILE A  80
 None
SAM  A 301 (-3.6A)
None
None
None
 0.87A 4xdrA-1eizA:
undetectable		 4xdrA-1eizA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.41A 5e9qA-1eizA:
14.7		 5e9qA-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.43A 5e9qC-1eizA:
14.6		 5e9qC-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 SER A  33
GLY A  59
GLY A  64
TRP A  65
ASP A 124
 SAM  A 301 ( 4.6A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.6A)
 0.64A 5ec8A-1eizA:
14.6		 5ec8A-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.35A 5ec8C-1eizA:
14.6		 5ec8C-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.40A 5ehgA-1eizA:
14.6		 5ehgA-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.43A 5ehiA-1eizA:
14.7		 5ehiA-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.37A 5ehiC-1eizA:
14.7		 5ehiC-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.41A 5eifA-1eizA:
14.7		 5eifA-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.38A 5eifC-1eizA:
14.6		 5eifC-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.43A 5eiwA-1eizA:
14.6		 5eiwA-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.39A 5eiwC-1eizA:
14.5		 5eiwC-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.39A 5ekxA-1eizA:
14.6		 5ekxA-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 SER A  33
GLY A  59
GLY A  64
TRP A  65
ASP A 124
 SAM  A 301 ( 4.6A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.6A)
 0.68A 5ekxA-1eizA:
14.6		 5ekxA-1eizA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.38A 5ikmA-1eizA:
14.7		 5ikmA-1eizA:
26.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 1eiz FTSJ
(Escherichia
coli) 		4 / 6 ILE A  80
GLY A  63
MET A  87
ILE A  79
 None
SAM  A 301 (-3.9A)
None
None
 0.88A 5j4nB-1eizA:
undetectable		 5j4nB-1eizA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.29A 5kqsA-1eizA:
14.9		 5kqsA-1eizA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.39A 5njvA-1eizA:
14.8		 5njvA-1eizA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.37A 5njvB-1eizA:
14.8		 5njvB-1eizA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 PHE A 161
LEU A  48
ARG A 207
GLY A 206
THR A 205
 None
 1.34A 5o4yD-1eizA:
undetectable
5o4yE-1eizA:
undetectable		 5o4yD-1eizA:
8.14
5o4yE-1eizA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 ALA A  61
PRO A  62
GLY A  64
ASP A  57
LEU A 109
 SAM  A 301 (-4.0A)
SAM  A 301 (-3.4A)
SAM  A 301 (-3.1A)
None
None
 1.15A 5wwsA-1eizA:
11.0		 5wwsA-1eizA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 1eiz FTSJ
(Escherichia
coli) 		7 / 12 ALA A  61
PRO A  62
GLY A  64
ASP A  83
ASP A  99
ASP A 124
LEU A 143
 SAM  A 301 (-4.0A)
SAM  A 301 (-3.4A)
SAM  A 301 (-3.1A)
SAM  A 301 (-2.8A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.6A)
 0.74A 5wwsA-1eizA:
11.0		 5wwsA-1eizA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 1eiz FTSJ
(Escherichia
coli) 		6 / 12 ALA A  61
PRO A  62
GLY A  64
ASP A  83
ASP A  99
ASP A 124
 SAM  A 301 (-4.0A)
SAM  A 301 (-3.4A)
SAM  A 301 (-3.1A)
SAM  A 301 (-2.8A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.63A 5wwsB-1eizA:
10.9		 5wwsB-1eizA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.43A 5wz1A-1eizA:
14.6		 5wz1A-1eizA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.45A 5wz1C-1eizA:
14.7		 5wz1C-1eizA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.49A 5wz1D-1eizA:
14.7		 5wz1D-1eizA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.42A 5wz1E-1eizA:
14.6		 5wz1E-1eizA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.51A 5wz1F-1eizA:
14.7		 5wz1F-1eizA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.46A 5wz1G-1eizA:
14.7		 5wz1G-1eizA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.46A 5wz1H-1eizA:
14.7		 5wz1H-1eizA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.35A 5wz2A-1eizA:
14.6		 5wz2A-1eizA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 1eiz FTSJ
(Escherichia
coli) 		5 / 12 GLY A  59
GLY A  64
TRP A  65
ASP A  99
ASP A 124
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.38A 5wz2B-1eizA:
14.8		 5wz2B-1eizA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 1eiz FTSJ
(Escherichia
coli) 		6 / 12 GLY A  59
GLY A  64
LEU A  84
ASP A  99
ASP A 124
MET A 125
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.3A)
 0.90A 5yn6A-1eizA:
14.8		 5yn6A-1eizA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 1eiz FTSJ
(Escherichia
coli) 		7 / 12 GLY A  59
GLY A  64
ASP A  83
LEU A  84
ASP A  99
ASP A 124
MET A 125
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-2.8A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.3A)
 0.90A 5yniA-1eizA:
14.7		 5yniA-1eizA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 1eiz FTSJ
(Escherichia
coli) 		7 / 12 GLY A  59
GLY A  64
ASP A  83
LEU A  84
ASP A  99
ASP A 124
MET A 125
 SAM  A 301 (-3.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-2.8A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.3A)
 0.88A 5ynmA-1eizA:
14.8		 5ynmA-1eizA:
22.11