SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eje'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICU_D_NIOD223_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1eje	FMN-BINDING PROTEIN (Methanothermobac ter thermautotrophic us)	4 / 5	GLY A 179 SER A 47 THR A 29 PHE A 182	SO4 A 301 (-3.4A) FMN A 401 (-3.3A) FMN A 401 ( 3.6A) FMN A 401 (-4.6A)	1.36A	1icuC-1ejeA: 0.0 1icuD-1ejeA: 0.0	1icuC-1ejeA: 23.26 1icuD-1ejeA: 23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UCB_B_017B202_1 (PROTEASE)	1eje	FMN-BINDING PROTEIN (Methanothermobac ter thermautotrophic us)	4 / 7	PRO A 122 ARG A 123 GLY A 129 PRO A 128	None	1.24A	3ucbB-1ejeA: undetectable	3ucbB-1ejeA: 18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5F9Z_A_HFGA702_0 (AMINOACYL-TRNA SYNTHETASE)	1eje	FMN-BINDING PROTEIN (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 166 GLY A 159 VAL A 171 PRO A 128 ARG A 157	None	1.32A	5f9zA-1ejeA: undetectable	5f9zA-1ejeA: 17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BP4_A_SAMA505_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC)	1eje	FMN-BINDING PROTEIN (Methanothermobac ter thermautotrophic us)	3 / 3	ILE A 41 ASN A 82 CYH A 133	None	0.73A	6bp4A-1ejeA: 0.0	6bp4A-1ejeA: 20.79

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ICU_D_NIOD223_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1eje","FMN-BINDING PROTEIN","Methanothermobacter thermautotrophicus",4,"GLY A 179;SER A  47;THR A  29;PHE A 182","SO4 A 301 (-3.4A);FMN A 401 (-3.3A);FMN A 401 ( 3.6A);FMN A 401 (-4.6A)","1.36A","1icuC-1ejeA:0.0;1icuD-1ejeA:0.0","1icuC-1ejeA:23.26;1icuD-1ejeA:23.26"],["3UCB_B_017B202_1","PROTEASE","1eje","FMN-BINDING PROTEIN","Methanothermobacter thermautotrophicus",4,"PRO A 122;ARG A 123;GLY A 129;PRO A 128","None","1.24A","3ucbB-1ejeA:undetectable","3ucbB-1ejeA:18.56"],["5F9Z_A_HFGA702_0","AMINOACYL-TRNA SYNTHETASE","1eje","FMN-BINDING PROTEIN","Methanothermobacter thermautotrophicus",5,"LEU A 166;GLY A 159;VAL A 171;PRO A 128;ARG A 157","None","1.32A","5f9zA-1ejeA:undetectable","5f9zA-1ejeA:17.21"],["6BP4_A_SAMA505_1","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC","1eje","FMN-BINDING PROTEIN","Methanothermobacter thermautotrophicus",3,"ILE A  41;ASN A  82;CYH A 133","None","0.73A","6bp4A-1ejeA:0.0","6bp4A-1ejeA:20.79"]]