SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ek0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 1ek0 PROTEIN (GTP-BINDING
PROTEIN YPT51)
(Saccharomyces
cerevisiae) 		5 / 9 VAL A  86
GLY A 119
GLN A  66
ASN A 120
GLY A  19
 None
None
GNP  A 501 ( 4.9A)
GNP  A 501 (-3.2A)
GNP  A 501 (-3.3A)
 1.43A 3kmoA-1ek0A:
undetectable		 3kmoA-1ek0A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1ek0 PROTEIN (GTP-BINDING
PROTEIN YPT51)
(Saccharomyces
cerevisiae) 		3 / 3 LYS A  36
LYS A  20
SER A  21
 None
GNP  A 501 (-2.7A)
MG  A 601 ( 2.0A)
 1.45A 5odiA-1ek0A:
2.2		 5odiA-1ek0A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 1ek0 PROTEIN (GTP-BINDING
PROTEIN YPT51)
(Saccharomyces
cerevisiae) 		4 / 4 VAL A 118
LEU A  12
ASN A 159
ASP A 162
 None
 1.24A 5vcyA-1ek0A:
undetectable		 5vcyA-1ek0A:
20.00