SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eks'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2REZ_A_ACTA155_0
(MULTIFUNCTIONAL
CYCLASE-DEHYDRATASE-
3-O-METHYL
TRANSFERASE TCMN)		 1eks MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
C
(Escherichia
coli) 		4 / 5 ARG A  96
GLY A 140
PRO A 141
PHE A  33
 None
 0.97A 2rezA-1eksA:
0.0		 2rezA-1eksA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 1eks MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
C
(Escherichia
coli) 		5 / 12 ILE A 126
THR A 125
LEU A  88
ASN A  87
VAL A  34
 None
 1.21A 2vn0A-1eksA:
undetectable		 2vn0A-1eksA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 1eks MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
C
(Escherichia
coli) 		4 / 7 ASN A  87
ALA A 119
ALA A 118
ALA A 122
 None
 0.76A 3a2qA-1eksA:
0.0		 3a2qA-1eksA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 1eks MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
C
(Escherichia
coli) 		4 / 7 ILE A  99
LEU A  88
ALA A 122
VAL A 121
 None
 0.72A 4g77A-1eksA:
undetectable		 4g77A-1eksA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 1eks MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
C
(Escherichia
coli) 		3 / 3 LYS A 147
LEU A 144
ALA A  28
 None
 0.79A 4iizA-1eksA:
undetectable		 4iizA-1eksA:
23.39