SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1elk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1elk TARGET OF MYB1
(Homo
sapiens) 		4 / 5 VAL A  98
SER A  91
VAL A  89
SER A  97
 None
 1.35A 2j9cA-1elkA:
0.0
2j9cB-1elkA:
0.0
2j9cC-1elkA:
0.0		 2j9cA-1elkA:
20.99
2j9cB-1elkA:
20.99
2j9cC-1elkA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1elk TARGET OF MYB1
(Homo
sapiens) 		4 / 7 SER A  97
VAL A  98
LYS A  55
SER A  91
 None
 1.19A 2j9cA-1elkA:
0.0
2j9cB-1elkA:
0.0
2j9cC-1elkA:
0.0		 2j9cA-1elkA:
20.99
2j9cB-1elkA:
20.99
2j9cC-1elkA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 1elk TARGET OF MYB1
(Homo
sapiens) 		4 / 9 ILE A  36
ALA A  70
VAL A  73
CYH A  77
 None
 0.77A 2vufB-1elkA:
0.3		 2vufB-1elkA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 1elk TARGET OF MYB1
(Homo
sapiens) 		3 / 3 ARG A  16
GLU A  35
SER A  24
 None
 0.89A 2xctD-1elkA:
0.8		 2xctD-1elkA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 1elk TARGET OF MYB1
(Homo
sapiens) 		4 / 6 LEU A  74
GLU A  75
LYS A 116
LEU A 120
 None
 0.80A 3h5gA-1elkA:
undetectable
3h5gC-1elkA:
undetectable		 3h5gA-1elkA:
12.10
3h5gC-1elkA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1elk TARGET OF MYB1
(Homo
sapiens) 		4 / 7 VAL A 113
VAL A 117
LEU A 120
VAL A  95
 None
 0.68A 3hs6B-1elkA:
undetectable		 3hs6B-1elkA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 1elk TARGET OF MYB1
(Homo
sapiens) 		5 / 12 VAL A  89
SER A  91
SER A  97
VAL A  54
LEU A  71
 None
 1.42A 3vt3A-1elkA:
0.9		 3vt3A-1elkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 1elk TARGET OF MYB1
(Homo
sapiens) 		4 / 6 CYH A  77
THR A  76
ASN A  80
ILE A  39
 None
 1.47A 3w9tB-1elkA:
undetectable		 3w9tB-1elkA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1elk TARGET OF MYB1
(Homo
sapiens) 		4 / 7 VAL A 113
VAL A 117
LEU A 120
VAL A  95
 None
 0.73A 4e1gB-1elkA:
undetectable		 4e1gB-1elkA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1elk TARGET OF MYB1
(Homo
sapiens) 		4 / 5 ILE A 140
ARG A 145
ASP A 126
VAL A  89
 None
 1.09A 4nkxC-1elkA:
undetectable		 4nkxC-1elkA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1elk TARGET OF MYB1
(Homo
sapiens) 		4 / 5 ILE A 140
ARG A 145
ASP A 126
VAL A  89
 None
 1.10A 4nkxD-1elkA:
undetectable		 4nkxD-1elkA:
17.26