SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1elv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		7 / 8 HIS A 460
ASP A 611
SER A 612
SER A 617
VAL A 638
GLY A 641
GLY A 648
 SO4  A2001 ( 3.9A)
None
None
SO4  A2001 ( 2.7A)
None
None
None
 0.54A 1aq7A-1elvA:
31.4		 1aq7A-1elvA:
30.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		6 / 9 ASP A 611
SER A 617
VAL A 638
TRP A 640
GLY A 641
GLY A 648
 None
SO4  A2001 ( 2.7A)
None
None
None
None
 0.40A 1bcuH-1elvA:
32.3		 1bcuH-1elvA:
28.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DWC_H_MITH1_1
(ALPHA-THROMBIN
(LARGE SUBUNIT))		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 9 HIS A 460
ASP A 611
SER A 617
TRP A 640
GLY A 648
 SO4  A2001 ( 3.9A)
None
SO4  A2001 ( 2.7A)
None
None
 0.45A 1dwcH-1elvA:
30.9		 1dwcH-1elvA:
28.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		7 / 12 HIS A 460
ASP A 611
SER A 617
VAL A 638
TRP A 640
GLY A 641
GLY A 648
 SO4  A2001 ( 3.9A)
None
SO4  A2001 ( 2.7A)
None
None
None
None
 0.63A 1etrH-1elvA:
30.8		 1etrH-1elvA:
28.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		6 / 8 ASP A 611
SER A 612
SER A 617
VAL A 638
GLY A 641
GLY A 648
 None
None
SO4  A2001 ( 2.7A)
None
None
None
 0.37A 1f5lA-1elvA:
30.3		 1f5lA-1elvA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4D_A_TOYA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 10 PHE A 511
ASP A 514
SER A 612
SER A 617
ALA A 445
 None
None
None
SO4  A2001 ( 2.7A)
None
 1.50A 1m4dA-1elvA:
0.0		 1m4dA-1elvA:
19.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TNL_A_TPAA900_1
(TRYPSIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		6 / 6 ASP A 611
SER A 612
SER A 617
VAL A 638
GLY A 641
GLY A 648
 None
None
SO4  A2001 ( 2.7A)
None
None
None
 0.29A 1tnlA-1elvA:
10.8		 1tnlA-1elvA:
30.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		6 / 6 ASP A 611
SER A 612
SER A 617
VAL A 638
GLY A 641
GLY A 648
 None
None
SO4  A2001 ( 2.7A)
None
None
None
 0.23A 2otvA-1elvA:
11.0		 2otvA-1elvA:
30.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		6 / 12 GLY A 556
GLY A 447
GLY A 618
GLY A 615
THR A 457
LEU A 456
 None
None
None
SO4  A2001 (-4.1A)
None
None
 1.41A 2oxtD-1elvA:
undetectable		 2oxtD-1elvA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		7 / 12 ASP A 611
SER A 617
VAL A 638
TRP A 640
GLY A 641
GLY A 648
TYR A 650
 None
SO4  A2001 ( 2.7A)
None
None
None
None
None
 0.35A 2p16A-1elvA:
31.4		 2p16A-1elvA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 12 LEU A 456
LEU A 517
VAL A 657
MET A 661
THR A 651
 None
 1.36A 2q7iA-1elvA:
undetectable		 2q7iA-1elvA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 12 LEU A 456
LEU A 517
VAL A 657
MET A 661
THR A 651
 None
 1.35A 2q7kA-1elvA:
undetectable		 2q7kA-1elvA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		6 / 8 ASP A 611
SER A 612
SER A 617
VAL A 638
GLY A 641
GLY A 648
 None
None
SO4  A2001 ( 2.7A)
None
None
None
 0.37A 2vinA-1elvA:
31.0		 2vinA-1elvA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		7 / 12 ASP A 611
SER A 617
VAL A 638
TRP A 640
GLY A 641
GLY A 648
TYR A 650
 None
SO4  A2001 ( 2.7A)
None
None
None
None
None
 0.35A 2w26A-1elvA:
31.4		 2w26A-1elvA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		6 / 12 ILE A 660
LEU A 535
ILE A 515
ILE A 533
PHE A 440
VAL A 461
 None
 1.28A 2ygqA-1elvA:
0.0		 2ygqA-1elvA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 12 LEU A 456
LEU A 517
VAL A 657
MET A 661
THR A 651
 None
 1.34A 2yloA-1elvA:
undetectable		 2yloA-1elvA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		3 / 3 PRO A 347
GLU A 385
TYR A 369
 None
 0.66A 2zmbA-1elvA:
undetectable		 2zmbA-1elvA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 11 THR A 663
ILE A 495
LEU A 456
ASN A 451
ILE A 515
 None
 1.26A 3a50B-1elvA:
undetectable		 3a50B-1elvA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 11 THR A 663
ILE A 495
LEU A 456
ASN A 451
ILE A 515
 None
 1.24A 3a50C-1elvA:
undetectable		 3a50C-1elvA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 12 THR A 663
ILE A 495
LEU A 456
ASN A 451
ILE A 515
 None
 1.22A 3a50E-1elvA:
undetectable		 3a50E-1elvA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 10 GLY A 556
ASP A 616
ILE A 552
LEU A 567
PHE A 434
 None
 1.30A 3ay0B-1elvA:
undetectable		 3ay0B-1elvA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		4 / 8 ILE A 602
TYR A 633
VAL A 623
GLY A 550
 None
 0.93A 3em0B-1elvA:
0.0		 3em0B-1elvA:
19.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		7 / 11 HIS A 460
ASP A 611
SER A 612
SER A 617
TRP A 640
GLY A 641
GLY A 648
 SO4  A2001 ( 3.9A)
None
None
SO4  A2001 ( 2.7A)
None
None
None
 0.38A 3gy3A-1elvA:
11.1		 3gy3A-1elvA:
30.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 12 HIS A 460
ASP A 514
LYS A 614
GLY A 615
SER A 617
 SO4  A2001 ( 3.9A)
None
SO4  A2001 (-2.9A)
SO4  A2001 (-4.1A)
SO4  A2001 ( 2.7A)
 0.90A 3keeA-1elvA:
12.0		 3keeA-1elvA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 12 HIS A 460
ASP A 514
LYS A 614
GLY A 615
SER A 617
 SO4  A2001 ( 3.9A)
None
SO4  A2001 (-2.9A)
SO4  A2001 (-4.1A)
SO4  A2001 ( 2.7A)
 0.89A 3keeB-1elvA:
12.0		 3keeB-1elvA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 12 HIS A 460
ASP A 514
LYS A 614
GLY A 615
SER A 617
 SO4  A2001 ( 3.9A)
None
SO4  A2001 (-2.9A)
SO4  A2001 (-4.1A)
SO4  A2001 ( 2.7A)
 0.90A 3keeC-1elvA:
11.7		 3keeC-1elvA:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		6 / 6 SER A 612
SER A 617
VAL A 638
TRP A 640
GLY A 641
GLY A 648
 None
SO4  A2001 ( 2.7A)
None
None
None
None
 0.38A 3rxfA-1elvA:
12.7		 3rxfA-1elvA:
30.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 5 ASP A 611
SER A 612
SER A 617
VAL A 638
GLY A 648
 None
None
SO4  A2001 ( 2.7A)
None
None
 0.31A 3rxhA-1elvA:
11.0		 3rxhA-1elvA:
30.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 12 HIS A 460
ASP A 514
LYS A 614
GLY A 615
SER A 617
 SO4  A2001 ( 3.9A)
None
SO4  A2001 (-2.9A)
SO4  A2001 (-4.1A)
SO4  A2001 ( 2.7A)
 0.83A 3sueA-1elvA:
11.3		 3sueA-1elvA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 12 HIS A 460
ASP A 514
LYS A 614
GLY A 615
SER A 617
 SO4  A2001 ( 3.9A)
None
SO4  A2001 (-2.9A)
SO4  A2001 (-4.1A)
SO4  A2001 ( 2.7A)
 0.88A 3sufA-1elvA:
11.2		 3sufA-1elvA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 12 LEU A 456
LEU A 517
VAL A 657
MET A 661
THR A 651
 None
 1.35A 3zqtA-1elvA:
undetectable		 3zqtA-1elvA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 12 ASN A 600
THR A 651
LEU A 637
ALA A 459
HIS A 496
 NES  A2003 (-3.2A)
None
None
None
NES  A2003 (-4.3A)
 1.37A 4ejwA-1elvA:
undetectable		 4ejwA-1elvA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_D_15UD402_1
(PROTHROMBIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 12 HIS A 460
ASP A 611
VAL A 638
TRP A 640
GLY A 648
 SO4  A2001 ( 3.9A)
None
None
None
None
 0.33A 4hfpD-1elvA:
31.2		 4hfpD-1elvA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 12 VAL A 653
GLY A 447
ILE A 515
LEU A 517
LEU A 449
 None
 1.00A 4qdjA-1elvA:
undetectable		 4qdjA-1elvA:
22.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		5 / 12 HIS A 460
VAL A 638
TRP A 640
GLY A 641
GLY A 648
 SO4  A2001 ( 3.9A)
None
None
None
None
 0.50A 4rn6B-1elvA:
28.1		 4rn6B-1elvA:
30.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 1elv COMPLEMENT C1S
COMPONENT
(Homo
sapiens) 		6 / 12 GLY A 556
GLY A 447
GLY A 618
GLY A 615
THR A 457
VAL A 455
 None
None
None
SO4  A2001 (-4.1A)
None
None
 1.30A 5eiwC-1elvA:
undetectable		 5eiwC-1elvA:
20.52