SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1em9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1em9 GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		3 / 3 ILE A  19
LEU A  22
VAL A  26
 None
 0.37A 1mz9B-1em9A:
0.0		 1mz9B-1em9A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 1em9 GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		4 / 5 ASP A  52
THR A 133
LEU A 129
LEU A  48
 None
 1.15A 1u18B-1em9A:
0.0		 1u18B-1em9A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1em9 GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		4 / 7 GLU A 128
GLY A 108
GLY A 119
ALA A 110
 None
 0.89A 5e26A-1em9A:
undetectable
5e26B-1em9A:
undetectable		 5e26A-1em9A:
17.32
5e26B-1em9A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1em9 GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		4 / 7 ALA A 110
GLU A 128
GLY A 108
GLY A 119
 None
 0.87A 5e26A-1em9A:
undetectable
5e26B-1em9A:
undetectable		 5e26A-1em9A:
17.32
5e26B-1em9A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1em9 GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		4 / 7 GLU A 128
GLY A 108
GLY A 119
ALA A 110
 None
 0.90A 5e26C-1em9A:
undetectable
5e26D-1em9A:
undetectable		 5e26C-1em9A:
17.32
5e26D-1em9A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1em9 GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		4 / 8 ALA A 110
GLU A 128
GLY A 108
GLY A 119
 None
 0.91A 5e26C-1em9A:
undetectable
5e26D-1em9A:
undetectable		 5e26C-1em9A:
17.32
5e26D-1em9A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1em9 GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		4 / 7 VAL A 143
VAL A  26
GLY A  62
TYR A  66
 None
 0.97A 5x80C-1em9A:
2.4
5x80D-1em9A:
2.3		 5x80C-1em9A:
24.55
5x80D-1em9A:
24.55