SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1emu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 1emu AXIN
(Homo
sapiens) 		5 / 12 LEU A 151
ALA A 157
ARG A 162
MET A 230
LEU A 130
 None
 1.46A 1ya3B-1emuA:
undetectable		 1ya3B-1emuA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1emu AXIN
(Homo
sapiens) 		4 / 8 PHE A 139
ARG A 140
ALA A 149
LEU A 152
 None
 0.78A 2o01A-1emuA:
undetectable		 2o01A-1emuA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1emu AXIN
(Homo
sapiens) 		4 / 8 ARG A 174
ASP A 220
GLN A 223
GLU A 225
 None
 1.31A 3dh0A-1emuA:
undetectable		 3dh0A-1emuA:
20.37