SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1emy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1emy MYOGLOBIN
(Elephas
maximus) 		5 / 12 ILE A 107
ALA A 110
PHE A  29
LEU A  32
LEU A  72
 HEM  A 154 ( 3.9A)
None
CYN  A 155 ( 4.9A)
None
HEM  A 154 ( 4.3A)
 0.93A 1xlsA-1emyA:
undetectable		 1xlsA-1emyA:
25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1emy MYOGLOBIN
(Elephas
maximus) 		5 / 12 ILE A 107
ALA A 110
PHE A  29
LEU A  32
LEU A  72
 HEM  A 154 ( 3.9A)
None
CYN  A 155 ( 4.9A)
None
HEM  A 154 ( 4.3A)
 0.93A 1xlsC-1emyA:
undetectable		 1xlsC-1emyA:
25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1emy MYOGLOBIN
(Elephas
maximus) 		5 / 12 ILE A 107
ALA A 110
PHE A  29
LEU A  32
LEU A  72
 HEM  A 154 ( 3.9A)
None
CYN  A 155 ( 4.9A)
None
HEM  A 154 ( 4.3A)
 0.93A 1xlsD-1emyA:
undetectable		 1xlsD-1emyA:
25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1emy MYOGLOBIN
(Elephas
maximus) 		5 / 12 ILE A 107
ALA A 110
PHE A  29
LEU A  32
LEU A  72
 HEM  A 154 ( 3.9A)
None
CYN  A 155 ( 4.9A)
None
HEM  A 154 ( 4.3A)
 1.01A 3dzuA-1emyA:
undetectable		 3dzuA-1emyA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 1emy MYOGLOBIN
(Elephas
maximus) 		5 / 12 ASP A 141
ILE A 142
ILE A 101
ALA A 144
TYR A 146
 None
 1.14A 3ohtA-1emyA:
undetectable
3ohtB-1emyA:
undetectable		 3ohtA-1emyA:
17.53
3ohtB-1emyA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1emy MYOGLOBIN
(Elephas
maximus) 		4 / 7 ILE A  99
PHE A  29
PHE A  33
LEU A  32
 HEM  A 154 (-4.1A)
CYN  A 155 ( 4.9A)
None
None
 0.86A 3v7pA-1emyA:
undetectable		 3v7pA-1emyA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1emy MYOGLOBIN
(Elephas
maximus) 		5 / 12 GLN A  64
PHE A  29
ARG A 139
ILE A 107
HIS A  97
 CYN  A 155 (-3.8A)
CYN  A 155 ( 4.9A)
None
HEM  A 154 ( 3.9A)
HEM  A 154 (-3.5A)
 1.21A 4c49D-1emyA:
undetectable		 4c49D-1emyA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 1emy MYOGLOBIN
(Elephas
maximus) 		4 / 7 PHE A  46
LEU A  49
GLU A  26
THR A  67
 None
None
None
HEM  A 154 ( 4.9A)
 0.99A 4wnvD-1emyA:
undetectable		 4wnvD-1emyA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 1emy MYOGLOBIN
(Elephas
maximus) 		4 / 6 LEU A   2
ASP A   4
ILE A  75
HIS A  82
 None
 0.96A 4xi3C-1emyA:
undetectable		 4xi3C-1emyA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1emy MYOGLOBIN
(Elephas
maximus) 		5 / 12 ILE A 107
ALA A 110
PHE A  29
LEU A  32
LEU A  72
 HEM  A 154 ( 3.9A)
None
CYN  A 155 ( 4.9A)
None
HEM  A 154 ( 4.3A)
 0.95A 6a5zL-1emyA:
undetectable		 6a5zL-1emyA:
16.77