SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1enf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 1enf ENTEROTOXIN H
(Staphylococcus
aureus) 		5 / 12 ASP A 190
ASN A 185
THR A  10
TYR A 153
TYR A  21
 None
SO4  A1003 (-3.7A)
None
None
None
 1.44A 4dajC-1enfA:
0.0		 4dajC-1enfA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1enf ENTEROTOXIN H
(Staphylococcus
aureus) 		5 / 12 VAL A 114
ASN A 210
GLY A 118
ASP A 117
GLY A 162
 None
 1.41A 4pevB-1enfA:
0.0		 4pevB-1enfA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1enf ENTEROTOXIN H
(Staphylococcus
aureus) 		4 / 6 ARG A 143
ILE A 140
GLN A  20
ILE A 152
 None
 1.03A 4w5tA-1enfA:
0.0		 4w5tA-1enfA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 1enf ENTEROTOXIN H
(Staphylococcus
aureus) 		3 / 3 TYR A 193
TYR A 153
GLN A  20
 None
 1.17A 5jsdB-1enfA:
0.0
5jsdC-1enfA:
0.0		 5jsdB-1enfA:
16.95
5jsdC-1enfA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 1enf ENTEROTOXIN H
(Staphylococcus
aureus) 		4 / 6 ARG A 143
ILE A 140
GLN A  20
ILE A 152
 None
 1.03A 6cbdA-1enfA:
0.0		 6cbdA-1enfA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 1enf ENTEROTOXIN H
(Staphylococcus
aureus) 		5 / 9 ASN A  22
ILE A 142
GLU A 122
VAL A 209
ILE A 164
 None
 1.32A 6hloA-1enfA:
undetectable		 6hloA-1enfA:
16.05