SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eo0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CC8_A_RBFA1067_1 (VNG1446H)	1eo0	TRANSCRIPTION ELONGATION FACTOR S-II (Saccharomyces cerevisiae)	3 / 3	PHE A 34 VAL A 65 TRP A 72	None	0.84A	2cc8A-1eo0A: undetectable	2cc8A-1eo0A: 23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CCB_A_RBFA1067_1 (VNG1446H)	1eo0	TRANSCRIPTION ELONGATION FACTOR S-II (Saccharomyces cerevisiae)	3 / 3	PHE A 34 VAL A 65 TRP A 72	None	0.83A	2ccbA-1eo0A: undetectable	2ccbA-1eo0A: 23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VX9_A_RBFA1064_1 (DODECIN)	1eo0	TRANSCRIPTION ELONGATION FACTOR S-II (Saccharomyces cerevisiae)	3 / 3	PHE A 34 VAL A 65 TRP A 72	None	0.83A	2vx9A-1eo0A: undetectable	2vx9A-1eo0A: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BRF_A_SORA2_0 (LIN-12 AND GLP-1 PHENOTYPE PROTEIN 1, ISOFORM A)	1eo0	TRANSCRIPTION ELONGATION FACTOR S-II (Saccharomyces cerevisiae)	3 / 3	LYS A 52 LYS A 45 VAL A 48	None	0.99A	3brfA-1eo0A: undetectable	3brfA-1eo0A: 9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P6V_E_RBFE201_1 (NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT B NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT E)	1eo0	TRANSCRIPTION ELONGATION FACTOR S-II (Saccharomyces cerevisiae)	4 / 5	HIS A 9 VAL A 8 GLU A 5 VAL A 48	None	1.33A	4p6vB-1eo0A: 2.6 4p6vE-1eo0A: undetectable	4p6vB-1eo0A: 12.05 4p6vE-1eo0A: 17.17

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2CC8_A_RBFA1067_1","VNG1446H","1eo0","TRANSCRIPTION ELONGATION FACTOR S-II","Saccharomyces cerevisiae",3,"PHE A  34;VAL A  65;TRP A  72","None","0.84A","2cc8A-1eo0A:undetectable","2cc8A-1eo0A:23.46"],["2CCB_A_RBFA1067_1","VNG1446H","1eo0","TRANSCRIPTION ELONGATION FACTOR S-II","Saccharomyces cerevisiae",3,"PHE A  34;VAL A  65;TRP A  72","None","0.83A","2ccbA-1eo0A:undetectable","2ccbA-1eo0A:23.46"],["2VX9_A_RBFA1064_1","DODECIN","1eo0","TRANSCRIPTION ELONGATION FACTOR S-II","Saccharomyces cerevisiae",3,"PHE A  34;VAL A  65;TRP A  72","None","0.83A","2vx9A-1eo0A:undetectable","2vx9A-1eo0A:18.18"],["3BRF_A_SORA2_0","LIN-12 AND GLP-1 PHENOTYPE PROTEIN 1, ISOFORM A","1eo0","TRANSCRIPTION ELONGATION FACTOR S-II","Saccharomyces cerevisiae",3,"LYS A  52;LYS A  45;VAL A  48","None","0.99A","3brfA-1eo0A:undetectable","3brfA-1eo0A:9.83"],["4P6V_E_RBFE201_1","NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT B;NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT E","1eo0","TRANSCRIPTION ELONGATION FACTOR S-II","Saccharomyces cerevisiae",4,"HIS A   9;VAL A   8;GLU A   5;VAL A  48","None","1.33A","4p6vB-1eo0A:2.6;4p6vE-1eo0A:undetectable","4p6vB-1eo0A:12.05;4p6vE-1eo0A:17.17"]]