SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eo1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q7L_A_TESA155_1 (ANDROGEN RECEPTOR)	1eo1	HYPOTHETICAL PROTEIN MTH1175 (Methanothermobac ter thermautotrophic us)	5 / 12	LEU A 82 ASN A 83 LEU A 85 GLY A 86 VAL A 66	None	1.16A	2q7lA-1eo1A: undetectable	2q7lA-1eo1A: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y0Q_A_PX9A201_1 (BETA-LACTOGLOBULIN)	1eo1	HYPOTHETICAL PROTEIN MTH1175 (Methanothermobac ter thermautotrophic us)	3 / 3	LYS A 2 ILE A 28 ILE A 42	None	0.64A	4y0qA-1eo1A: 0.0	4y0qA-1eo1A: 22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J4N_B_AG2B501_1 (ARGININE/AGMATINE ANTIPORTER)	1eo1	HYPOTHETICAL PROTEIN MTH1175 (Methanothermobac ter thermautotrophic us)	4 / 6	ILE A 28 GLY A 34 ASN A 35 ILE A 3	None	0.83A	5j4nB-1eo1A: undetectable	5j4nB-1eo1A: 13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KOX_A_RFPA502_2 (PENTACHLOROPHENOL 4-MONOOXYGENASE)	1eo1	HYPOTHETICAL PROTEIN MTH1175 (Methanothermobac ter thermautotrophic us)	3 / 3	VAL A 97 ARG A 22 PRO A 24	None	0.85A	5koxA-1eo1A: 0.0	5koxA-1eo1A: 15.24

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Q7L_A_TESA155_1","ANDROGEN RECEPTOR","1eo1","HYPOTHETICAL PROTEIN MTH1175","Methanothermobacter thermautotrophicus",5,"LEU A  82;ASN A  83;LEU A  85;GLY A  86;VAL A  66","None","1.16A","2q7lA-1eo1A:undetectable","2q7lA-1eo1A:19.53"],["4Y0Q_A_PX9A201_1","BETA-LACTOGLOBULIN","1eo1","HYPOTHETICAL PROTEIN MTH1175","Methanothermobacter thermautotrophicus",3,"LYS A   2;ILE A  28;ILE A  42","None","0.64A","4y0qA-1eo1A:0.0","4y0qA-1eo1A:22.98"],["5J4N_B_AG2B501_1","ARGININE\/AGMATINE ANTIPORTER","1eo1","HYPOTHETICAL PROTEIN MTH1175","Methanothermobacter thermautotrophicus",4,"ILE A  28;GLY A  34;ASN A  35;ILE A   3","None","0.83A","5j4nB-1eo1A:undetectable","5j4nB-1eo1A:13.69"],["5KOX_A_RFPA502_2","PENTACHLOROPHENOL 4-MONOOXYGENASE","1eo1","HYPOTHETICAL PROTEIN MTH1175","Methanothermobacter thermautotrophicus",3,"VAL A  97;ARG A  22;PRO A  24","None","0.85A","5koxA-1eo1A:0.0","5koxA-1eo1A:15.24"]]