SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eo8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 1eo8 ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		4 / 4 THR H 117
PRO H 147
THR H 116
PRO H 118
 None
 1.30A 1dsdC-1eo8H:
undetectable		 1dsdC-1eo8H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 1eo8 ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		4 / 4 THR H 117
PRO H 147
THR H 116
PRO H 118
 None
 1.30A 1dsdC-1eo8H:
undetectable		 1dsdC-1eo8H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 1eo8 ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		4 / 7 PHE H 146
LEU H 170
THR H 117
TYR H 145
 None
 1.26A 1rmtB-1eo8H:
undetectable		 1rmtB-1eo8H:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 1eo8 ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		5 / 12 VAL H 163
VAL H 181
SER H 179
ASN H 196
ASN H 155
 None
 1.43A 3nyaA-1eo8H:
undetectable		 3nyaA-1eo8H:
18.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 1eo8 ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  94
TYR H 102
 None
 0.38A 4m7kH-1eo8H:
27.2		 4m7kH-1eo8H:
72.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1eo8 ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		3 / 3 PRO H  16
LEU H  82
GLN H  81
 None
 0.72A 4pevB-1eo8H:
undetectable		 4pevB-1eo8H:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 1eo8 ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		4 / 6 ASN H  76
ALA H  24
PRO H  52
TYR H  27
 None
 1.07A 5umd2-1eo8H:
0.0
5umdF-1eo8H:
0.0		 5umd2-1eo8H:
15.42
5umdF-1eo8H:
15.21