SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eo9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9A_A_BEZA306_0 (CHLOROCATECHOL 1,2-DIOXYGENASE)	1eo9	PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN (Acinetobacter sp. ADP1)	5 / 11	TYR B 408 TYR B 447 ARG B 457 HIS B 460 HIS B 462	FE B 600 ( 4.1A) FE B 600 ( 4.6A) SO4 B 999 (-4.0A) FE B 600 ( 3.4A) FE B 600 ( 3.4A)	0.39A	1s9aA-1eo9B: 12.3	1s9aA-1eo9B: 27.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9A_B_BEZB307_0 (CHLOROCATECHOL 1,2-DIOXYGENASE)	1eo9	PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN (Acinetobacter sp. ADP1)	5 / 12	ILE B 491 TYR B 408 HIS B 460 HIS B 462 GLN B 477	None FE B 600 ( 4.1A) FE B 600 ( 3.4A) FE B 600 ( 3.4A) SO4 B 999 (-3.6A)	1.48A	1s9aB-1eo9B: 13.2	1s9aB-1eo9B: 27.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9A_B_BEZB307_0 (CHLOROCATECHOL 1,2-DIOXYGENASE)	1eo9	PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN (Acinetobacter sp. ADP1)	7 / 12	TYR B 408 TYR B 447 ARG B 457 HIS B 460 HIS B 462 GLN B 477 CYH B 489	FE B 600 ( 4.1A) FE B 600 ( 4.6A) SO4 B 999 (-4.0A) FE B 600 ( 3.4A) FE B 600 ( 3.4A) SO4 B 999 (-3.6A) None	1.42A	1s9aB-1eo9B: 13.2	1s9aB-1eo9B: 27.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TMX_A_BEZA881_0 (HYDROXYQUINOL 1,2-DIOXYGENASE)	1eo9	PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN (Acinetobacter sp. ADP1)	5 / 11	TYR B 408 TYR B 447 ARG B 457 HIS B 460 HIS B 462	FE B 600 ( 4.1A) FE B 600 ( 4.6A) SO4 B 999 (-4.0A) FE B 600 ( 3.4A) FE B 600 ( 3.4A)	0.33A	1tmxA-1eo9B: 11.9	1tmxA-1eo9B: 27.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TMX_B_BEZB882_0 (HYDROXYQUINOL 1,2-DIOXYGENASE)	1eo9	PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN (Acinetobacter sp. ADP1)	5 / 12	TYR B 408 TYR B 447 ARG B 457 HIS B 460 HIS B 462	FE B 600 ( 4.1A) FE B 600 ( 4.6A) SO4 B 999 (-4.0A) FE B 600 ( 3.4A) FE B 600 ( 3.4A)	0.37A	1tmxB-1eo9B: 12.7	1tmxB-1eo9B: 27.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z9H_D_IMND476_1 (MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2)	1eo9	PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN (Acinetobacter sp. ADP1)	5 / 12	ILE B 461 VAL B 399 TYR B 437 ILE B 525 VAL B 380	None	1.18A	1z9hD-1eo9B: undetectable	1z9hD-1eo9B: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HGI_A_BEZA284_0 (CATECHOL 1,2-DIOXYGENASE)	1eo9	PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN (Acinetobacter sp. ADP1)	5 / 12	TYR B 408 TYR B 447 ARG B 457 HIS B 460 HIS B 462	FE B 600 ( 4.1A) FE B 600 ( 4.6A) SO4 B 999 (-4.0A) FE B 600 ( 3.4A) FE B 600 ( 3.4A)	0.39A	3hgiA-1eo9B: 12.1	3hgiA-1eo9B: 27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PEO_F_CU9F301_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1eo9	PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN (Acinetobacter sp. ADP1)	4 / 6	GLN B 477 TYR B 479 ILE B 486 SER B 476	SO4 B 999 (-3.6A) None None None	1.13A	3peoG-1eo9B: 0.0	3peoG-1eo9B: 23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PEO_F_CU9F301_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1eo9	PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN (Acinetobacter sp. ADP1)	4 / 6	GLN B 477 TYR B 479 ILE B 505 SER B 476	SO4 B 999 (-3.6A) None None None	1.20A	3peoG-1eo9B: 0.0	3peoG-1eo9B: 23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MWX_A_ZMRA513_2 (NEURAMINIDASE)	1eo9	PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN (Acinetobacter sp. ADP1)	3 / 3	ARG B 457 TRP B 449 ILE B 491	SO4 B 999 (-4.0A) None None	0.70A	4mwxA-1eo9B: undetectable	4mwxA-1eo9B: 21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ODQ_A_ACTA703_0 (HETERODISULFIDE REDUCTASE, SUBUNIT A)	1eo9	PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN (Acinetobacter sp. ADP1)	4 / 6	ARG B 473 ALA B 348 PRO B 349 PHE B 351	None	1.24A	5odqA-1eo9B: undetectable	5odqA-1eo9B: 16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_A_CVIA301_1 (REGULATORY PROTEIN TETR)	1eo9	PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN (Acinetobacter sp. ADP1)	4 / 8	GLY B 435 ARG B 522 VAL B 384 ASP B 524	None	1.06A	5vlmA-1eo9B: undetectable	5vlmA-1eo9B: 20.97

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1S9A_A_BEZA306_0","CHLOROCATECHOL 1,2-DIOXYGENASE","1eo9","PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN;","Acinetobacter sp. ADP1",5,"TYR B 408;TYR B 447;ARG B 457;HIS B 460;HIS B 462"," FE B 600 ( 4.1A); FE B 600 ( 4.6A);SO4 B 999 (-4.0A); FE B 600 ( 3.4A); FE B 600 ( 3.4A)","0.39A","1s9aA-1eo9B:12.3","1s9aA-1eo9B:27.82"],["1S9A_B_BEZB307_0","CHLOROCATECHOL 1,2-DIOXYGENASE","1eo9","PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN;","Acinetobacter sp. ADP1",5,"ILE B 491;TYR B 408;HIS B 460;HIS B 462;GLN B 477","None; FE B 600 ( 4.1A); FE B 600 ( 3.4A); FE B 600 ( 3.4A);SO4 B 999 (-3.6A)","1.48A","1s9aB-1eo9B:13.2","1s9aB-1eo9B:27.82"],["1S9A_B_BEZB307_0","CHLOROCATECHOL 1,2-DIOXYGENASE","1eo9","PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN;","Acinetobacter sp. ADP1",7,"TYR B 408;TYR B 447;ARG B 457;HIS B 460;HIS B 462;GLN B 477;CYH B 489"," FE B 600 ( 4.1A); FE B 600 ( 4.6A);SO4 B 999 (-4.0A); FE B 600 ( 3.4A); FE B 600 ( 3.4A);SO4 B 999 (-3.6A);None","1.42A","1s9aB-1eo9B:13.2","1s9aB-1eo9B:27.82"],["1TMX_A_BEZA881_0","HYDROXYQUINOL 1,2-DIOXYGENASE","1eo9","PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN;","Acinetobacter sp. ADP1",5,"TYR B 408;TYR B 447;ARG B 457;HIS B 460;HIS B 462"," FE B 600 ( 4.1A); FE B 600 ( 4.6A);SO4 B 999 (-4.0A); FE B 600 ( 3.4A); FE B 600 ( 3.4A)","0.33A","1tmxA-1eo9B:11.9","1tmxA-1eo9B:27.07"],["1TMX_B_BEZB882_0","HYDROXYQUINOL 1,2-DIOXYGENASE","1eo9","PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN;","Acinetobacter sp. ADP1",5,"TYR B 408;TYR B 447;ARG B 457;HIS B 460;HIS B 462"," FE B 600 ( 4.1A); FE B 600 ( 4.6A);SO4 B 999 (-4.0A); FE B 600 ( 3.4A); FE B 600 ( 3.4A)","0.37A","1tmxB-1eo9B:12.7","1tmxB-1eo9B:27.07"],["1Z9H_D_IMND476_1","MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2","1eo9",";PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN","Acinetobacter sp. ADP1",5,"ILE B 461;VAL B 399;TYR B 437;ILE B 525;VAL B 380","None","1.18A","1z9hD-1eo9B:undetectable","1z9hD-1eo9B:20.60"],["3HGI_A_BEZA284_0","CATECHOL 1,2-DIOXYGENASE","1eo9","PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN;","Acinetobacter sp. ADP1",5,"TYR B 408;TYR B 447;ARG B 457;HIS B 460;HIS B 462"," FE B 600 ( 4.1A); FE B 600 ( 4.6A);SO4 B 999 (-4.0A); FE B 600 ( 3.4A); FE B 600 ( 3.4A)","0.39A","3hgiA-1eo9B:12.1","3hgiA-1eo9B:27.78"],["3PEO_F_CU9F301_2","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","1eo9",";PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN","Acinetobacter sp. ADP1",4,"GLN B 477;TYR B 479;ILE B 486;SER B 476","SO4 B 999 (-3.6A);None;None;None","1.13A","3peoG-1eo9B:0.0","3peoG-1eo9B:23.69"],["3PEO_F_CU9F301_2","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","1eo9",";PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN","Acinetobacter sp. ADP1",4,"GLN B 477;TYR B 479;ILE B 505;SER B 476","SO4 B 999 (-3.6A);None;None;None","1.20A","3peoG-1eo9B:0.0","3peoG-1eo9B:23.69"],["4MWX_A_ZMRA513_2","NEURAMINIDASE","1eo9",";PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN","Acinetobacter sp. ADP1",3,"ARG B 457;TRP B 449;ILE B 491","SO4 B 999 (-4.0A);None;None","0.70A","4mwxA-1eo9B:undetectable","4mwxA-1eo9B:21.63"],["5ODQ_A_ACTA703_0","HETERODISULFIDE REDUCTASE, SUBUNIT A","1eo9","PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN;","Acinetobacter sp. ADP1",4,"ARG B 473;ALA B 348;PRO B 349;PHE B 351","None","1.24A","5odqA-1eo9B:undetectable","5odqA-1eo9B:16.18"],["5VLM_A_CVIA301_1","REGULATORY PROTEIN TETR","1eo9","PROTOCATECHUATE 3,4-DIOXYGENASE BETA CHAIN;","Acinetobacter sp. ADP1",4,"GLY B 435;ARG B 522;VAL B 384;ASP B 524","None","1.06A","5vlmA-1eo9B:undetectable","5vlmA-1eo9B:20.97"]]